4E4V

The crystal structure of the dimeric human importin alpha 1 at 2.5 angstrom resolution.

Summary for 4E4V

DescriptorImportin subunit alpha-2, GLYCEROL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, ... (4 entities in total)
Functional Keywordsarmadillo repeat, karyopherin, importin, nuclear import, host-virus interaction, nucleus, phosphoprotein, protein transport, transport, transport protein
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm  P52292
Total number of polymer chains2
Total molecular weight106836.79
Authors
Hang, P.C.,Miknis, Z.M.,Franke, W.A.,Umland, T.C.,Schultz, L.W. (deposition date: 2012-03-13, release date: 2013-05-29, Last modification date: 2017-11-15)
Primary citation
Hang, P.C.,Miknis, Z.J.,Franke, W.A.,Umland, T.C.,Schultz, L.W.
The crystal structure of the dimeric human importin alpha 1 at 2.5 angstrom resolution.
To be Published,
Experimental method
X-RAY DIFFRACTION (2.5283 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.2106 0.2% 4.1% 3.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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PDB entries from 2020-12-02