PDB: 297 件ウェブページステータス検索Chemie searchBIRD

---

6ZIC	CRYSTAL STRUCTURE OF RAT PEROXISOMAL MULTIFUNCTIONAL ENZYME TYPE-1 (RPMFE1) COMPLEXED WITH 3S-HYDROXYBUTANOYL-COA AND NADH 分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 3-HYDROXYBUTANOYL-COENZYME A, GLYCEROL, ... 著者 Wierenga, R.K, Sridhar, S, Kiema, T.R. 登録日 2020-06-25 公開日 2021-07-07 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 CRYSTAL STRUCTURE OF RAT PEROXISOMAL MULTIFUNCTIONAL ENZYME TYPE-1 (RPMFE1) COMPLEXED WITH 3S-HYDROXYBUTANOYL-COA AND NADH To Be Published
8OQN	Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with Fragment-M-53 分子名称: 1-benzyl-1H-pyrazole-4-carboxylic acid, 3-hydroxyacyl-CoA dehydrogenase, GLYCEROL, ... 著者 Dalwani, S, Wierenga, R.K, Venkatesan, R. 登録日 2023-04-12 公開日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystallographic fragment binding studies of the Mycobacterium tuberculosis trifunctional enzyme suggest binding pockets for the tails of the acyl-CoA substrates at its active sites and a potential substrate channeling path between them Biorxiv, 2024
2IEX	Crystal structure of dihydroxynapthoic acid synthetase (GK2873) from Geobacillus kaustophilus HTA426 分子名称: Dihydroxynapthoic acid synthetase 著者 Jeyakanthan, J, Kanaujia, S.P, Vasuki Ranjani, C, Sekar, K, BaBa, S, Ebihara, A, Kuramitsu, S, Shinkai, A, Shiro, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2006-09-19 公開日 2007-10-02 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of dihydroxynapthoic acid synthetase (GK2873) from Geobacillus kaustophilus HTA426 To be Published
3QXI	Crystal structure of enoyl-CoA hydratase EchA1 from Mycobacterium marinum 分子名称: Enoyl-CoA hydratase EchA1 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2011-03-01 公開日 2011-03-16 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
3QMJ	Crystal structure of Enoyl-CoA hydratase EchA8_6 from Mycobacterium marinum 分子名称: Enoyl-CoA hydratase, EchA8_6, FORMIC ACID 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2011-02-04 公開日 2011-03-09 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
1XX4	Crystal Structure of Rat Mitochondrial 3,2-Enoyl-CoA 分子名称: 3,2-trans-enoyl-CoA isomerase, mitochondrial, BENZAMIDINE, ... 著者 Hubbard, P.A, Yu, W, Schulz, H, Kim, J.-J. 登録日 2004-11-03 公開日 2004-11-23 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Domain swapping in the low-similarity isomerase/hydratase superfamily: the crystal structure of rat mitochondrial Delta3, Delta2-enoyl-CoA isomerase. Protein Sci., 14, 2005
2ZQQ	Crystal structure of human AUH (3-methylglutaconyl-coa hydratase) mixed with (AUUU)24A RNA 分子名称: Methylglutaconyl-CoA hydratase 著者 Kurimoto, K, Kuwasako, K, Muto, Y, Nureki, O, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2008-08-16 公開日 2009-06-30 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 AU-rich RNA-binding induces changes in the quaternary structure of AUH Proteins, 75, 2009
4JYJ	Crystal Structure of putative enoyl-CoA hydratase/isomerase from Novosphingobium aromaticivorans DSM 12444 分子名称: Enoyl-CoA hydratase/isomerase, UNKNOWN LIGAND 著者 Cooper, D.R, Porebski, P.J, Domagalski, M.J, Ahmed, M, Stead, M, Hillerich, B, Seidel, R, Zimmerman, M, Bonanno, J.B, Almo, S.C, Minor, W, New York Structural Genomics Research Consortium (NYSGRC) 登録日 2013-03-29 公開日 2013-05-29 最終更新日 2022-04-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal Structure of putative enoyl-CoA hydratase/isomerase from Novosphingobium aromaticivorans DSM 12444 To be Published
5Z7R	Crystal structure of crotonase from Clostridium acetobutylicum 分子名称: Short-chain-enoyl-CoA hydratase 著者 Kim, E.-J, Kim, Y.-J, Kim, K.-J. 登録日 2018-01-30 公開日 2018-02-14 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural insights into substrate specificity of crotonase from the n-butanol producing bacterium Clostridium acetobutylicum. Biochem. Biophys. Res. Commun., 451, 2014
3R9S	Structure of a carnitinyl-CoA dehydratase from Mycobacterium avium 104 分子名称: 1,2-ETHANEDIOL, BENZOIC ACID, Carnitinyl-CoA dehydratase 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2011-03-25 公開日 2011-04-13 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
1HZD	CRYSTAL STRUCTURE OF HUMAN AUH PROTEIN, AN RNA-BINDING HOMOLOGUE OF ENOYL-COA HYDRATASE 分子名称: AU-BINDING PROTEIN/ENOYL-COA HYDRATASE 著者 Kurimoto, K, Fukai, S, Nureki, O, Muto, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2001-01-24 公開日 2001-12-12 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of human AUH protein, a single-stranded RNA binding homolog of enoyl-CoA hydratase. Structure, 9, 2001
4QIJ	Crystal structure of MenB from Mycobacteria tuberculosis in complex with 1-HNA-CoA 分子名称: 1,4-Dihydroxy-2-naphthoyl-CoA synthase, 1-hydroxy-2-naphthoyl-CoA 著者 Song, H.G, Sung, H.P, Tse, Y.S, Guo, Z.H. 登録日 2014-05-31 公開日 2014-11-19 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Ligand-dependent active-site closure revealed in the crystal structure of Mycobacterium tuberculosis MenB complexed with product analogues Acta Crystallogr.,Sect.D, 70, 2014
4FJW	Crystal Structure of the apo form of the E131Q Mtb crotonase 分子名称: Probable enoyl-CoA hydratase echA8 著者 Bruning, J.B, Delgado, E, Ghosh, S, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) 登録日 2012-06-12 公開日 2013-05-22 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal Structure and Mechanism of the Prokaryotic Crotonase To be Published
2FW2	Catalytic domain of CDY 分子名称: Testis-specific chromodomain protein Y 2 著者 Min, J.R, Antoshenko, T, Wu, H, Weigelt, J, Sundstrom, M, Arrowsmith, C, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC) 登録日 2006-01-31 公開日 2006-02-14 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The Crystal Structure of catalytic domain of Human Testis-specific chromodomain protein Y. To be Published
3NJB	Crystal structure of enoyl-coa hydratase from Mycobacterium smegmatis, iodide soak 分子名称: Enoyl-CoA hydratase, IODIDE ION 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2010-06-17 公開日 2010-07-28 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 SAD phasing using iodide ions in a high-throughput structural genomics environment. J.Struct.Funct.Genom., 12, 2011
2VSS	Wild-type Hydroxycinnamoyl-CoA hydratase lyase in complex with acetyl- CoA and vanillin 分子名称: 4-hydroxy-3-methoxybenzaldehyde, ACETYL COENZYME *A, P-HYDROXYCINNAMOYL COA HYDRATASE/LYASE 著者 Bennett, J.P, Bertin, L.M, Brzozowski, A.M, Walton, N.J, Grogan, G. 登録日 2008-04-29 公開日 2008-05-27 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.22 Å) 主引用文献 A Ternary Complex of Hydroxycinnamoyl-Coa Hydratase-Lyase (Hchl) with Acetyl-Coa and Vanillin Gives Insights Into Substrate Specificity and Mechanism. Biochem.J., 414, 2008
8PF8	Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with Fragment-M-72 分子名称: (2~{R})-3-bis[2-methyl-5-(trifluoromethyl)pyrazol-3-yl]boranyloxypropane-1,2-diol, 3-hydroxyacyl-CoA dehydrogenase, GLYCEROL, ... 著者 Dalwani, S, Wierenga, R.K, Venkatesan, R. 登録日 2023-06-15 公開日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.23 Å) 主引用文献 Crystallographic fragment binding studies of the Mycobacterium tuberculosis trifunctional enzyme suggest binding pockets for the tails of the acyl-CoA substrates at its active sites and a potential substrate channeling path between them Biorxiv, 2024
5DU8	Crystal structure of M. tuberculosis EchA6 bound to GSK572A 分子名称: (5R,7S)-5-(4-ethylphenyl)-N-[(5-fluoropyridin-2-yl)methyl]-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide, Probable enoyl-CoA hydratase echA6 著者 Cox, J.A.G, Besra, G.S, Futterer, K. 登録日 2015-09-18 公開日 2016-01-20 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.23 Å) 主引用文献 THPP target assignment reveals EchA6 as an essential fatty acid shuttle in mycobacteria. Nat Microbiol, 1, 2016
3PZK	Crystal Structure of the Mycobacterium tuberculosis crotonase in apo form 分子名称: SULFATE ION, e enoyl-CoA hydratase echA8 著者 Bruning, J.B, Delgado, E, Ghosh, S, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) 登録日 2010-12-14 公開日 2011-03-23 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.2303 Å) 主引用文献 Crystal Structure of the Prokaryotic Crotonase To be Published
2A7K	carboxymethylproline synthase (CarB) from pectobacterium carotovora, apo enzyme 分子名称: CarB 著者 Sleeman, M.C, Sorensen, J.L, Batchelar, E.T, McDonough, M.A, Schofield, C.J. 登録日 2005-07-05 公開日 2005-08-23 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.24 Å) 主引用文献 Structural and Mechanistic Studies on Carboxymethylproline Synthase (CarB), a Unique Member of the Crotonase Superfamily Catalyzing the First Step in Carbapenem Biosynthesis. J.Biol.Chem., 280, 2005
3T8A	Crystal structure of Mycobacterium tuberculosis MenB in complex with substrate analogue, OSB-NCoA 分子名称: 1,4-Dihydroxy-2-naphthoyl-CoA synthase, o-succinylbenzoyl-N-coenzyme A 著者 Li, H.-J, Li, X, Liu, N, Zhang, H, Truglio, J, Mishra, S, Kisker, C, Garcia-Diaz, M, Tonge, P. 登録日 2011-08-01 公開日 2011-08-24 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.245 Å) 主引用文献 Mechanism of the Intramolecular Claisen Condensation Reaction Catalyzed by MenB, a Crotonase Superfamily Member. Biochemistry, 50, 2011
5WYB	Structure of Pseudomonas aeruginosa DspI 分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, ACETATE ION, Probable enoyl-CoA hydratase/isomerase 著者 Liu, L, Peng, C, Li, T, Li, C, He, L, Song, Y, Zhu, Y, Shen, Y, Bao, R. 登録日 2017-01-12 公開日 2018-01-17 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Structural and functional studies on Pseudomonas aeruginosa DspI: implications for its role in DSF biosynthesis. Sci Rep, 8, 2018
6Z5F	CRYSTAL STRUCTURE OF RAT PEROXISOMAL MULTIFUNCTIONAL ENZYME TYPE-1 (RPMFE1) COMPLEXED WITH 3-KETODECANOYL-COA AND OXIDISED NICOTINAMIDE ADENINE DINUCLEOTIDE 分子名称: 3-KETO-DECANOYL-COA, GLYCEROL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... 著者 Wierenga, R.K, Sridhar, S, Kiema, T.R. 登録日 2020-05-26 公開日 2020-12-09 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Crystallographic binding studies of rat peroxisomal multifunctional enzyme type 1 with 3-ketodecanoyl-CoA: capturing active and inactive states of its hydratase and dehydrogenase catalytic sites. Acta Crystallogr D Struct Biol, 76, 2020
4DI1	Crystal structure of enoyl-CoA hydratase EchA17 from Mycobacterium marinum 分子名称: 1,2-ETHANEDIOL, Enoyl-CoA hydratase EchA17 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2012-01-30 公開日 2012-02-08 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
4JFC	Crystal structure of a enoyl-CoA hydratase from Polaromonas sp. JS666 分子名称: Enoyl-CoA hydratase, GLYCEROL 著者 Kumaran, D, Chamala, S, Evans, B, Foti, R, Gizzi, A, Hillerich, B, Kar, A, Lafleur, J, Seidel, R, Villigas, G, Zencheck, W, Al Obaidi, N, Almo, S.C, Swaminathan, S, New York Structural Genomics Research Consortium (NYSGRC) 登録日 2013-02-28 公開日 2013-05-01 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Crystal structure of a enoyl-CoA hydratase from Polaromonas sp. JS666 To be Published

<123456789101112>