4QIJ

Crystal structure of MenB from Mycobacteria tuberculosis in complex with 1-HNA-CoA

Summary for 4QIJ

• Entry DOI: 10.2210/pdb4qij/pdb
• Related: 4QII
• Descriptor: 1,4-Dihydroxy-2-naphthoyl-CoA synthase, 1-hydroxy-2-naphthoyl-CoA (3 entities in total)
• Functional Keywords: 1, 4-dihydroxy-2-naphthoyl-coenzyme a synthase, menb, 1-hna-coa, lyase
• Biological source: Mycobacterium tuberculosis H37Rv
• Total number of polymer chains: 12
• Total formula weight: 454091.99

Authors

Song, H.G.,Sung, H.P.,Tse, Y.S.,Guo, Z.H. (deposition date: 2014-05-31, release date: 2014-11-19, Last modification date: 2023-11-08)

• Primary citation: Song, H.,Sung, H.P.,Tse, Y.S.,Jiang, M.,Guo, Z.H.; Ligand-dependent active-site closure revealed in the crystal structure of Mycobacterium tuberculosis MenB complexed with product analogues; Acta Crystallogr.,Sect.D, 70:2959-2969, 2014; PubMed: 25372686; DOI: 10.1107/S1399004714019440

Experimental method

X-RAY DIFFRACTION (2.2 Å)