4QIJ
Crystal structure of MenB from Mycobacteria tuberculosis in complex with 1-HNA-CoA
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0005886 | cellular_component | plasma membrane |
A | 0008935 | molecular_function | 1,4-dihydroxy-2-naphthoyl-CoA synthase activity |
A | 0009234 | biological_process | menaquinone biosynthetic process |
A | 0016829 | molecular_function | lyase activity |
A | 0034214 | biological_process | protein hexamerization |
B | 0005886 | cellular_component | plasma membrane |
B | 0008935 | molecular_function | 1,4-dihydroxy-2-naphthoyl-CoA synthase activity |
B | 0009234 | biological_process | menaquinone biosynthetic process |
B | 0016829 | molecular_function | lyase activity |
B | 0034214 | biological_process | protein hexamerization |
C | 0005886 | cellular_component | plasma membrane |
C | 0008935 | molecular_function | 1,4-dihydroxy-2-naphthoyl-CoA synthase activity |
C | 0009234 | biological_process | menaquinone biosynthetic process |
C | 0016829 | molecular_function | lyase activity |
C | 0034214 | biological_process | protein hexamerization |
D | 0005886 | cellular_component | plasma membrane |
D | 0008935 | molecular_function | 1,4-dihydroxy-2-naphthoyl-CoA synthase activity |
D | 0009234 | biological_process | menaquinone biosynthetic process |
D | 0016829 | molecular_function | lyase activity |
D | 0034214 | biological_process | protein hexamerization |
E | 0005886 | cellular_component | plasma membrane |
E | 0008935 | molecular_function | 1,4-dihydroxy-2-naphthoyl-CoA synthase activity |
E | 0009234 | biological_process | menaquinone biosynthetic process |
E | 0016829 | molecular_function | lyase activity |
E | 0034214 | biological_process | protein hexamerization |
F | 0005886 | cellular_component | plasma membrane |
F | 0008935 | molecular_function | 1,4-dihydroxy-2-naphthoyl-CoA synthase activity |
F | 0009234 | biological_process | menaquinone biosynthetic process |
F | 0016829 | molecular_function | lyase activity |
F | 0034214 | biological_process | protein hexamerization |
G | 0005886 | cellular_component | plasma membrane |
G | 0008935 | molecular_function | 1,4-dihydroxy-2-naphthoyl-CoA synthase activity |
G | 0009234 | biological_process | menaquinone biosynthetic process |
G | 0016829 | molecular_function | lyase activity |
G | 0034214 | biological_process | protein hexamerization |
H | 0005886 | cellular_component | plasma membrane |
H | 0008935 | molecular_function | 1,4-dihydroxy-2-naphthoyl-CoA synthase activity |
H | 0009234 | biological_process | menaquinone biosynthetic process |
H | 0016829 | molecular_function | lyase activity |
H | 0034214 | biological_process | protein hexamerization |
I | 0005886 | cellular_component | plasma membrane |
I | 0008935 | molecular_function | 1,4-dihydroxy-2-naphthoyl-CoA synthase activity |
I | 0009234 | biological_process | menaquinone biosynthetic process |
I | 0016829 | molecular_function | lyase activity |
I | 0034214 | biological_process | protein hexamerization |
J | 0005886 | cellular_component | plasma membrane |
J | 0008935 | molecular_function | 1,4-dihydroxy-2-naphthoyl-CoA synthase activity |
J | 0009234 | biological_process | menaquinone biosynthetic process |
J | 0016829 | molecular_function | lyase activity |
J | 0034214 | biological_process | protein hexamerization |
K | 0005886 | cellular_component | plasma membrane |
K | 0008935 | molecular_function | 1,4-dihydroxy-2-naphthoyl-CoA synthase activity |
K | 0009234 | biological_process | menaquinone biosynthetic process |
K | 0016829 | molecular_function | lyase activity |
K | 0034214 | biological_process | protein hexamerization |
L | 0005886 | cellular_component | plasma membrane |
L | 0008935 | molecular_function | 1,4-dihydroxy-2-naphthoyl-CoA synthase activity |
L | 0009234 | biological_process | menaquinone biosynthetic process |
L | 0016829 | molecular_function | lyase activity |
L | 0034214 | biological_process | protein hexamerization |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 29 |
Details | BINDING SITE FOR RESIDUE 1HA A 401 |
Chain | Residue |
A | GLU56 |
A | ASP106 |
A | GLN107 |
A | TYR115 |
A | LEU134 |
A | ILE136 |
A | TRP157 |
A | GLY161 |
A | THR184 |
A | ASP185 |
A | SER190 |
A | VAL57 |
A | HOH602 |
A | HOH605 |
A | HOH617 |
A | HOH685 |
F | PHE299 |
F | LYS302 |
F | HOH649 |
L | ALA14 |
L | LEU15 |
L | HOH576 |
A | ARG58 |
A | ALA60 |
A | PHE61 |
A | LYS95 |
A | SER103 |
A | GLY104 |
A | GLY105 |
site_id | AC2 |
Number of Residues | 33 |
Details | BINDING SITE FOR RESIDUE 1HA B 401 |
Chain | Residue |
B | GLU56 |
B | VAL57 |
B | ARG58 |
B | ALA60 |
B | LYS95 |
B | SER103 |
B | GLY104 |
B | GLY105 |
B | ASP106 |
B | GLN107 |
B | TYR115 |
B | ILE136 |
B | LEU137 |
B | TRP157 |
B | GLY161 |
B | THR184 |
B | ASP185 |
B | SER190 |
B | PHE191 |
B | HOH518 |
B | HOH551 |
B | HOH567 |
B | HOH578 |
B | HOH591 |
B | HOH608 |
B | HOH655 |
B | HOH688 |
B | HOH694 |
B | HOH707 |
E | PHE299 |
E | LYS302 |
K | ALA14 |
K | LEU15 |
site_id | AC3 |
Number of Residues | 32 |
Details | BINDING SITE FOR RESIDUE 1HA C 401 |
Chain | Residue |
C | GLU56 |
C | VAL57 |
C | ARG58 |
C | ALA60 |
C | LYS95 |
C | SER103 |
C | GLY104 |
C | GLY105 |
C | ASP106 |
C | GLN107 |
C | TYR115 |
C | ILE136 |
C | LEU137 |
C | TRP157 |
C | GLY161 |
C | THR184 |
C | ASP185 |
C | SER190 |
C | PHE191 |
C | HOH525 |
C | HOH532 |
C | HOH579 |
C | HOH584 |
C | HOH585 |
C | HOH623 |
C | HOH625 |
C | HOH638 |
C | HOH685 |
D | PHE299 |
D | LYS302 |
J | ALA14 |
J | LEU15 |
site_id | AC4 |
Number of Residues | 27 |
Details | BINDING SITE FOR RESIDUE 1HA D 401 |
Chain | Residue |
D | ALA60 |
D | LYS95 |
D | SER103 |
D | GLY104 |
D | GLY105 |
D | ASP106 |
D | GLN107 |
D | TYR115 |
D | ILE136 |
D | TRP157 |
D | GLY161 |
D | THR184 |
D | ASP185 |
D | SER190 |
D | PHE191 |
D | HOH604 |
D | HOH618 |
D | HOH628 |
D | HOH649 |
I | HOH585 |
I | HOH616 |
I | HOH701 |
C | PHE299 |
C | LYS302 |
C | HOH630 |
D | VAL57 |
D | ARG58 |
site_id | AC5 |
Number of Residues | 27 |
Details | BINDING SITE FOR RESIDUE 1HA E 401 |
Chain | Residue |
B | PHE299 |
B | LYS302 |
E | GLU56 |
E | VAL57 |
E | ARG58 |
E | ALA60 |
E | LYS95 |
E | SER103 |
E | GLY104 |
E | GLY105 |
E | ASP106 |
E | GLN107 |
E | ILE136 |
E | LEU137 |
E | TRP157 |
E | GLY160 |
E | GLY161 |
E | THR184 |
E | ASP185 |
E | VAL188 |
E | SER190 |
E | PHE191 |
E | ASP192 |
E | HOH562 |
E | HOH568 |
E | HOH576 |
E | HOH611 |
site_id | AC6 |
Number of Residues | 28 |
Details | BINDING SITE FOR RESIDUE 1HA F 401 |
Chain | Residue |
A | PHE299 |
A | LYS302 |
F | GLU56 |
F | VAL57 |
F | ARG58 |
F | ALA60 |
F | LYS95 |
F | SER103 |
F | GLY104 |
F | GLY105 |
F | ASP106 |
F | GLN107 |
F | TYR115 |
F | ILE136 |
F | LEU137 |
F | TRP157 |
F | GLY161 |
F | THR184 |
F | ASP185 |
F | VAL188 |
F | SER190 |
F | PHE191 |
F | HOH512 |
F | HOH517 |
F | HOH539 |
F | HOH550 |
F | HOH553 |
F | HOH612 |
site_id | AC7 |
Number of Residues | 24 |
Details | BINDING SITE FOR RESIDUE 1HA G 401 |
Chain | Residue |
G | GLU56 |
G | VAL57 |
G | ARG58 |
G | ALA60 |
G | LYS95 |
G | SER103 |
G | GLY104 |
G | GLY105 |
G | ASP106 |
G | GLN107 |
G | TYR115 |
G | LEU137 |
G | TRP157 |
G | GLY161 |
G | THR184 |
G | ASP185 |
G | VAL188 |
G | SER190 |
G | PHE191 |
G | HOH537 |
G | HOH594 |
K | PHE299 |
K | LYS302 |
L | SER119 |
site_id | AC8 |
Number of Residues | 27 |
Details | BINDING SITE FOR RESIDUE 1HA H 401 |
Chain | Residue |
H | GLU56 |
H | VAL57 |
H | ARG58 |
H | ALA60 |
H | LYS95 |
H | SER103 |
H | GLY104 |
H | GLY105 |
H | ASP106 |
H | GLN107 |
H | TYR115 |
H | ILE136 |
H | LEU137 |
H | TRP157 |
H | GLY161 |
H | THR184 |
H | ASP185 |
H | VAL188 |
H | SER190 |
H | PHE191 |
H | HOH547 |
H | HOH623 |
H | HOH631 |
H | HOH642 |
J | PHE299 |
J | LYS302 |
J | HOH580 |
site_id | AC9 |
Number of Residues | 34 |
Details | BINDING SITE FOR RESIDUE 1HA I 401 |
Chain | Residue |
I | GLU56 |
I | VAL57 |
I | ARG58 |
I | ALA60 |
I | LYS95 |
I | SER103 |
I | GLY104 |
I | GLY105 |
I | ASP106 |
I | GLN107 |
I | TYR115 |
I | ILE136 |
I | LEU137 |
I | TRP157 |
I | GLY160 |
I | GLY161 |
I | THR184 |
I | ASP185 |
I | VAL188 |
I | SER190 |
I | PHE191 |
I | HOH526 |
I | HOH558 |
I | HOH569 |
I | HOH584 |
I | HOH599 |
I | HOH601 |
I | HOH614 |
I | HOH655 |
I | HOH666 |
I | HOH679 |
I | HOH681 |
L | PHE299 |
L | LYS302 |
site_id | BC1 |
Number of Residues | 31 |
Details | BINDING SITE FOR RESIDUE 1HA J 401 |
Chain | Residue |
C | ALA14 |
C | LEU15 |
H | PHE299 |
H | LYS302 |
J | GLU56 |
J | VAL57 |
J | ARG58 |
J | ALA60 |
J | LYS95 |
J | SER103 |
J | GLY104 |
J | GLY105 |
J | ASP106 |
J | GLN107 |
J | TYR115 |
J | ILE136 |
J | TRP157 |
J | GLY161 |
J | THR184 |
J | ASP185 |
J | VAL188 |
J | SER190 |
J | PHE191 |
J | HOH514 |
J | HOH545 |
J | HOH554 |
J | HOH557 |
J | HOH594 |
J | HOH612 |
J | HOH672 |
J | HOH722 |
site_id | BC2 |
Number of Residues | 33 |
Details | BINDING SITE FOR RESIDUE 1HA K 401 |
Chain | Residue |
B | ALA14 |
B | LEU15 |
G | PHE299 |
G | LYS302 |
G | HOH584 |
K | GLU56 |
K | VAL57 |
K | ARG58 |
K | ALA60 |
K | LYS95 |
K | SER103 |
K | GLY104 |
K | GLY105 |
K | ASP106 |
K | GLN107 |
K | TYR115 |
K | ILE136 |
K | LEU137 |
K | TRP157 |
K | GLY160 |
K | GLY161 |
K | THR184 |
K | ASP185 |
K | SER190 |
K | PHE191 |
K | HOH521 |
K | HOH524 |
K | HOH559 |
K | HOH580 |
K | HOH589 |
K | HOH665 |
K | HOH673 |
K | HOH695 |
site_id | BC3 |
Number of Residues | 31 |
Details | BINDING SITE FOR RESIDUE 1HA L 401 |
Chain | Residue |
A | ALA14 |
A | LEU15 |
I | PHE299 |
I | LYS302 |
I | HOH595 |
L | VAL57 |
L | ARG58 |
L | ALA60 |
L | SER103 |
L | GLY104 |
L | GLY105 |
L | ASP106 |
L | GLN107 |
L | TYR115 |
L | TRP157 |
L | GLY161 |
L | THR184 |
L | ASP185 |
L | VAL188 |
L | SER190 |
L | PHE191 |
L | HOH565 |
L | HOH617 |
L | HOH624 |
L | HOH632 |
L | HOH663 |
L | HOH723 |
L | HOH724 |
L | HOH728 |
L | HOH732 |
L | HOH748 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 12 |
Details | BINDING: in other chain => ECO:0000255|HAMAP-Rule:MF_01934, ECO:0000269|PubMed:12909628, ECO:0000269|PubMed:21830810 |
Chain | Residue | Details |
A | ARG58 | |
J | ARG58 | |
K | ARG58 | |
L | ARG58 | |
B | ARG58 | |
C | ARG58 | |
D | ARG58 | |
E | ARG58 | |
F | ARG58 | |
G | ARG58 | |
H | ARG58 | |
I | ARG58 |
site_id | SWS_FT_FI2 |
Number of Residues | 12 |
Details | BINDING: in other chain => ECO:0000269|PubMed:12909628, ECO:0000269|PubMed:21830810 |
Chain | Residue | Details |
A | LYS95 | |
J | LYS95 | |
K | LYS95 | |
L | LYS95 | |
B | LYS95 | |
C | LYS95 | |
D | LYS95 | |
E | LYS95 | |
F | LYS95 | |
G | LYS95 | |
H | LYS95 | |
I | LYS95 |
site_id | SWS_FT_FI3 |
Number of Residues | 12 |
Details | BINDING: in other chain => ECO:0000255|HAMAP-Rule:MF_01934, ECO:0000269|PubMed:12909628, ECO:0000269|PubMed:16131752, ECO:0000269|PubMed:21830810 |
Chain | Residue | Details |
A | SER103 | |
J | SER103 | |
K | SER103 | |
L | SER103 | |
B | SER103 | |
C | SER103 | |
D | SER103 | |
E | SER103 | |
F | SER103 | |
G | SER103 | |
H | SER103 | |
I | SER103 |
site_id | SWS_FT_FI4 |
Number of Residues | 12 |
Details | BINDING: in other chain => ECO:0000250|UniProtKB:P0ABU0, ECO:0000255|HAMAP-Rule:MF_01934 |
Chain | Residue | Details |
A | TYR115 | |
J | TYR115 | |
K | TYR115 | |
L | TYR115 | |
B | TYR115 | |
C | TYR115 | |
D | TYR115 | |
E | TYR115 | |
F | TYR115 | |
G | TYR115 | |
H | TYR115 | |
I | TYR115 |
site_id | SWS_FT_FI5 |
Number of Residues | 24 |
Details | BINDING: in other chain => ECO:0000255|HAMAP-Rule:MF_01934, ECO:0000269|PubMed:12909628 |
Chain | Residue | Details |
A | TRP157 | |
E | THR184 | |
F | TRP157 | |
F | THR184 | |
G | TRP157 | |
G | THR184 | |
H | TRP157 | |
H | THR184 | |
I | TRP157 | |
I | THR184 | |
J | TRP157 | |
A | THR184 | |
J | THR184 | |
K | TRP157 | |
K | THR184 | |
L | TRP157 | |
L | THR184 | |
B | TRP157 | |
B | THR184 | |
C | TRP157 | |
C | THR184 | |
D | TRP157 | |
D | THR184 | |
E | TRP157 |
site_id | SWS_FT_FI6 |
Number of Residues | 12 |
Details | BINDING: in other chain => ECO:0000255|HAMAP-Rule:MF_01934, ECO:0000305|PubMed:21830810 |
Chain | Residue | Details |
A | SER190 | |
J | SER190 | |
K | SER190 | |
L | SER190 | |
B | SER190 | |
C | SER190 | |
D | SER190 | |
E | SER190 | |
F | SER190 | |
G | SER190 | |
H | SER190 | |
I | SER190 |
site_id | SWS_FT_FI7 |
Number of Residues | 24 |
Details | BINDING: BINDING => ECO:0000250|UniProtKB:P0ABU0, ECO:0000255|HAMAP-Rule:MF_01934 |
Chain | Residue | Details |
A | TYR287 | |
E | LYS302 | |
F | TYR287 | |
F | LYS302 | |
G | TYR287 | |
G | LYS302 | |
H | TYR287 | |
H | LYS302 | |
I | TYR287 | |
I | LYS302 | |
J | TYR287 | |
A | LYS302 | |
J | LYS302 | |
K | TYR287 | |
K | LYS302 | |
L | TYR287 | |
L | LYS302 | |
B | TYR287 | |
B | LYS302 | |
C | TYR287 | |
C | LYS302 | |
D | TYR287 | |
D | LYS302 | |
E | TYR287 |
site_id | SWS_FT_FI8 |
Number of Residues | 12 |
Details | SITE: Important for catalysis => ECO:0000250|UniProtKB:P0ABU0, ECO:0000255|HAMAP-Rule:MF_01934 |
Chain | Residue | Details |
A | TYR115 | |
J | TYR115 | |
K | TYR115 | |
L | TYR115 | |
B | TYR115 | |
C | TYR115 | |
D | TYR115 | |
E | TYR115 | |
F | TYR115 | |
G | TYR115 | |
H | TYR115 | |
I | TYR115 |
site_id | SWS_FT_FI9 |
Number of Residues | 12 |
Details | SITE: Important for catalysis => ECO:0000255|HAMAP-Rule:MF_01934, ECO:0000305|PubMed:20643650, ECO:0000305|PubMed:21830810 |
Chain | Residue | Details |
A | ASP185 | |
J | ASP185 | |
K | ASP185 | |
L | ASP185 | |
B | ASP185 | |
C | ASP185 | |
D | ASP185 | |
E | ASP185 | |
F | ASP185 | |
G | ASP185 | |
H | ASP185 | |
I | ASP185 |
site_id | SWS_FT_FI10 |
Number of Residues | 12 |
Details | SITE: Important for catalysis => ECO:0000250|UniProtKB:P0ABU0, ECO:0000255|HAMAP-Rule:MF_01934, ECO:0000305|PubMed:12909628 |
Chain | Residue | Details |
A | TYR287 | |
J | TYR287 | |
K | TYR287 | |
L | TYR287 | |
B | TYR287 | |
C | TYR287 | |
D | TYR287 | |
E | TYR287 | |
F | TYR287 | |
G | TYR287 | |
H | TYR287 | |
I | TYR287 |
Catalytic Information from CSA
site_id | MCSA1 |
Number of Residues | 6 |
Details | M-CSA 346 |
Chain | Residue | Details |
A | GLY105 | electrostatic stabiliser, hydrogen bond donor |
A | TYR115 | electrostatic stabiliser, hydrogen bond donor, steric role |
A | GLY161 | electrostatic stabiliser, hydrogen bond donor |
A | ASP185 | activator |
A | SER190 | activator |
A | TYR287 | electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, polar interaction, proton acceptor, proton donor, steric role |
site_id | MCSA10 |
Number of Residues | 6 |
Details | M-CSA 346 |
Chain | Residue | Details |
J | GLY105 | electrostatic stabiliser, hydrogen bond donor |
J | TYR115 | electrostatic stabiliser, hydrogen bond donor, steric role |
J | GLY161 | electrostatic stabiliser, hydrogen bond donor |
J | ASP185 | activator |
J | SER190 | activator |
J | TYR287 | electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, polar interaction, proton acceptor, proton donor, steric role |
site_id | MCSA11 |
Number of Residues | 6 |
Details | M-CSA 346 |
Chain | Residue | Details |
K | GLY105 | electrostatic stabiliser, hydrogen bond donor |
K | TYR115 | electrostatic stabiliser, hydrogen bond donor, steric role |
K | GLY161 | electrostatic stabiliser, hydrogen bond donor |
K | ASP185 | activator |
K | SER190 | activator |
K | TYR287 | electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, polar interaction, proton acceptor, proton donor, steric role |
site_id | MCSA12 |
Number of Residues | 6 |
Details | M-CSA 346 |
Chain | Residue | Details |
L | GLY105 | electrostatic stabiliser, hydrogen bond donor |
L | TYR115 | electrostatic stabiliser, hydrogen bond donor, steric role |
L | GLY161 | electrostatic stabiliser, hydrogen bond donor |
L | ASP185 | activator |
L | SER190 | activator |
L | TYR287 | electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, polar interaction, proton acceptor, proton donor, steric role |
site_id | MCSA2 |
Number of Residues | 6 |
Details | M-CSA 346 |
Chain | Residue | Details |
B | GLY105 | electrostatic stabiliser, hydrogen bond donor |
B | TYR115 | electrostatic stabiliser, hydrogen bond donor, steric role |
B | GLY161 | electrostatic stabiliser, hydrogen bond donor |
B | ASP185 | activator |
B | SER190 | activator |
B | TYR287 | electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, polar interaction, proton acceptor, proton donor, steric role |
site_id | MCSA3 |
Number of Residues | 6 |
Details | M-CSA 346 |
Chain | Residue | Details |
C | GLY105 | electrostatic stabiliser, hydrogen bond donor |
C | TYR115 | electrostatic stabiliser, hydrogen bond donor, steric role |
C | GLY161 | electrostatic stabiliser, hydrogen bond donor |
C | ASP185 | activator |
C | SER190 | activator |
C | TYR287 | electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, polar interaction, proton acceptor, proton donor, steric role |
site_id | MCSA4 |
Number of Residues | 6 |
Details | M-CSA 346 |
Chain | Residue | Details |
D | GLY105 | electrostatic stabiliser, hydrogen bond donor |
D | TYR115 | electrostatic stabiliser, hydrogen bond donor, steric role |
D | GLY161 | electrostatic stabiliser, hydrogen bond donor |
D | ASP185 | activator |
D | SER190 | activator |
D | TYR287 | electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, polar interaction, proton acceptor, proton donor, steric role |
site_id | MCSA5 |
Number of Residues | 6 |
Details | M-CSA 346 |
Chain | Residue | Details |
E | GLY105 | electrostatic stabiliser, hydrogen bond donor |
E | TYR115 | electrostatic stabiliser, hydrogen bond donor, steric role |
E | GLY161 | electrostatic stabiliser, hydrogen bond donor |
E | ASP185 | activator |
E | SER190 | activator |
E | TYR287 | electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, polar interaction, proton acceptor, proton donor, steric role |
site_id | MCSA6 |
Number of Residues | 6 |
Details | M-CSA 346 |
Chain | Residue | Details |
F | GLY105 | electrostatic stabiliser, hydrogen bond donor |
F | TYR115 | electrostatic stabiliser, hydrogen bond donor, steric role |
F | GLY161 | electrostatic stabiliser, hydrogen bond donor |
F | ASP185 | activator |
F | SER190 | activator |
F | TYR287 | electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, polar interaction, proton acceptor, proton donor, steric role |
site_id | MCSA7 |
Number of Residues | 6 |
Details | M-CSA 346 |
Chain | Residue | Details |
G | GLY105 | electrostatic stabiliser, hydrogen bond donor |
G | TYR115 | electrostatic stabiliser, hydrogen bond donor, steric role |
G | GLY161 | electrostatic stabiliser, hydrogen bond donor |
G | ASP185 | activator |
G | SER190 | activator |
G | TYR287 | electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, polar interaction, proton acceptor, proton donor, steric role |
site_id | MCSA8 |
Number of Residues | 6 |
Details | M-CSA 346 |
Chain | Residue | Details |
H | GLY105 | electrostatic stabiliser, hydrogen bond donor |
H | TYR115 | electrostatic stabiliser, hydrogen bond donor, steric role |
H | GLY161 | electrostatic stabiliser, hydrogen bond donor |
H | ASP185 | activator |
H | SER190 | activator |
H | TYR287 | electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, polar interaction, proton acceptor, proton donor, steric role |
site_id | MCSA9 |
Number of Residues | 6 |
Details | M-CSA 346 |
Chain | Residue | Details |
I | GLY105 | electrostatic stabiliser, hydrogen bond donor |
I | TYR115 | electrostatic stabiliser, hydrogen bond donor, steric role |
I | GLY161 | electrostatic stabiliser, hydrogen bond donor |
I | ASP185 | activator |
I | SER190 | activator |
I | TYR287 | electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, polar interaction, proton acceptor, proton donor, steric role |