2ZQQ

Crystal structure of human AUH (3-methylglutaconyl-coa hydratase) mixed with (AUUU)24A RNA

Summary for 2ZQQ

• Entry DOI: 10.2210/pdb2zqq/pdb
• Related: 1HZD 1V4M 2E8K
• Descriptor: Methylglutaconyl-CoA hydratase (2 entities in total)
• Functional Keywords: beta spiral, lyase, branched-chain amino acid catabolism, disease mutation, mitochondrion, rna-binding, transit peptide, structural genomics, nppsfa, national project on protein structural and functional analyses, riken structural genomics/proteomics initiative, rsgi
• Biological source: Homo sapiens (human)
• Cellular location: Mitochondrion (By similarity): Q13825
• Total number of polymer chains: 6
• Total formula weight: 175428.92

Authors

Kurimoto, K.,Kuwasako, K.,Muto, Y.,Nureki, O.,Yokoyama, S.,RIKEN Structural Genomics/Proteomics Initiative (RSGI) (deposition date: 2008-08-16, release date: 2009-06-30, Last modification date: 2023-11-01)

• Primary citation: Kurimoto, K.,Kuwasako, K.,Sandercock, A.M.,Unzai, S.,Robinson, C.V.,Muto, Y.,Yokoyama, S.; AU-rich RNA-binding induces changes in the quaternary structure of AUH; Proteins, 75:360-372, 2009; PubMed: 18831052; DOI: 10.1002/prot.22246

Experimental method

X-RAY DIFFRACTION (2.2 Å)