2ZQQ

Crystal structure of human AUH (3-methylglutaconyl-coa hydratase) mixed with (AUUU)24A RNA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
B	0003824	molecular_function	catalytic activity
C	0003824	molecular_function	catalytic activity
D	0003824	molecular_function	catalytic activity
E	0003824	molecular_function	catalytic activity
F	0003824	molecular_function	catalytic activity

Functional Information from PROSITE/UniProt

site_id	PS00166
Number of Residues	21
Details	ENOYL_COA_HYDRATASE Enoyl-CoA hydratase/isomerase signature. IAaIDGlalGGGlelaLaCDI

Chain	Residue	Details
A	ILE176-ILE196

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	84
Details	Region: {"description":"RNA-binding","evidences":[{"source":"PubMed","id":"11738050","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	29
Details	Modified residue: {"description":"N6-succinyllysine; alternate","evidences":[{"source":"UniProtKB","id":"Q9JLZ3","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	23
Details	Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"Q9JLZ3","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

Catalytic Information from CSA

site_id	CSA1
Number of Residues	4
Details	Annotated By Reference To The Literature 1dub

Chain	Residue	Details
A	GLU209
A	GLY186
A	GLU189
A	ALA141

---

site_id	CSA10
Number of Residues	2
Details	Annotated By Reference To The Literature 1dub

Chain	Residue	Details
D	GLU209
D	GLY217

---

site_id	CSA11
Number of Residues	2
Details	Annotated By Reference To The Literature 1dub

Chain	Residue	Details
E	GLU209
E	GLY217

---

site_id	CSA12
Number of Residues	2
Details	Annotated By Reference To The Literature 1dub

Chain	Residue	Details
F	GLU209
F	GLY217

---

site_id	CSA13
Number of Residues	3
Details	Annotated By Reference To The Literature 1dub

Chain	Residue	Details
A	GLU209
A	GLY186
A	GLU189

---

site_id	CSA14
Number of Residues	3
Details	Annotated By Reference To The Literature 1dub

Chain	Residue	Details
B	GLU209
B	GLY186
B	GLU189

---

site_id	CSA15
Number of Residues	3
Details	Annotated By Reference To The Literature 1dub

Chain	Residue	Details
C	GLU209
C	GLY186
C	GLU189

---

site_id	CSA16
Number of Residues	3
Details	Annotated By Reference To The Literature 1dub

Chain	Residue	Details
D	GLU209
D	GLY186
D	GLU189

---

site_id	CSA17
Number of Residues	3
Details	Annotated By Reference To The Literature 1dub

Chain	Residue	Details
E	GLU209
E	GLY186
E	GLU189

---

site_id	CSA18
Number of Residues	3
Details	Annotated By Reference To The Literature 1dub

Chain	Residue	Details
F	GLU209
F	GLY186
F	GLU189

---

site_id	CSA2
Number of Residues	4
Details	Annotated By Reference To The Literature 1dub

Chain	Residue	Details
B	GLU209
B	GLY186
B	GLU189
B	ALA141

---

site_id	CSA3
Number of Residues	4
Details	Annotated By Reference To The Literature 1dub

Chain	Residue	Details
C	GLU209
C	GLY186
C	GLU189
C	ALA141

---

site_id	CSA4
Number of Residues	4
Details	Annotated By Reference To The Literature 1dub

Chain	Residue	Details
D	GLU209
D	GLY186
D	GLU189
D	ALA141

---

site_id	CSA5
Number of Residues	4
Details	Annotated By Reference To The Literature 1dub

Chain	Residue	Details
E	GLU209
E	GLY186
E	GLU189
E	ALA141

---

site_id	CSA6
Number of Residues	4
Details	Annotated By Reference To The Literature 1dub

Chain	Residue	Details
F	GLU209
F	GLY186
F	GLU189
F	ALA141

---

site_id	CSA7
Number of Residues	2
Details	Annotated By Reference To The Literature 1dub

Chain	Residue	Details
A	GLU209
A	GLY217

---

site_id	CSA8
Number of Residues	2
Details	Annotated By Reference To The Literature 1dub

Chain	Residue	Details
B	GLU209
B	GLY217

---

site_id	CSA9
Number of Residues	2
Details	Annotated By Reference To The Literature 1dub

Chain	Residue	Details
C	GLU209
C	GLY217

---

site_id	MCSA1
Number of Residues	4
Details	M-CSA 343

Chain	Residue	Details
A	ALA141	electrostatic stabiliser, hydrogen bond donor
A	GLY186	electrostatic stabiliser, hydrogen bond donor
A	GLU189	hydrogen bond acceptor
A	GLU209	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor

---

site_id	MCSA2
Number of Residues	4
Details	M-CSA 343

Chain	Residue	Details
B	ALA141	electrostatic stabiliser, hydrogen bond donor
B	GLY186	electrostatic stabiliser, hydrogen bond donor
B	GLU189	hydrogen bond acceptor
B	GLU209	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor

---

site_id	MCSA3
Number of Residues	4
Details	M-CSA 343

Chain	Residue	Details
C	ALA141	electrostatic stabiliser, hydrogen bond donor
C	GLY186	electrostatic stabiliser, hydrogen bond donor
C	GLU189	hydrogen bond acceptor
C	GLU209	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor

---

site_id	MCSA4
Number of Residues	4
Details	M-CSA 343

Chain	Residue	Details
D	ALA141	electrostatic stabiliser, hydrogen bond donor
D	GLY186	electrostatic stabiliser, hydrogen bond donor
D	GLU189	hydrogen bond acceptor
D	GLU209	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor

---

site_id	MCSA5
Number of Residues	4
Details	M-CSA 343

Chain	Residue	Details
E	ALA141	electrostatic stabiliser, hydrogen bond donor
E	GLY186	electrostatic stabiliser, hydrogen bond donor
E	GLU189	hydrogen bond acceptor
E	GLU209	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor

---

site_id	MCSA6
Number of Residues	4
Details	M-CSA 343

Chain	Residue	Details
F	ALA141	electrostatic stabiliser, hydrogen bond donor
F	GLY186	electrostatic stabiliser, hydrogen bond donor
F	GLU189	hydrogen bond acceptor
F	GLU209	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor

---