4W8I
 
 | | Crystal structure of LpSPL/Lpp2128, Legionella pneumophila sphingosine-1 phosphate lyase | | 分子名称: | Probable sphingosine-1-phosphate lyase | | 著者 | Stogios, P.J, Daniels, C, Skarina, T, Cuff, M, Di Leo, R, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2014-08-24 | | 公開日 | 2014-11-05 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Legionella pneumophila S1P-lyase targets host sphingolipid metabolism and restrains autophagy.
Proc.Natl.Acad.Sci.USA, 113, 2016
|
|
5K1R
 | |
5O5C
 | | The crystal structure of DfoJ, the desferrioxamine biosynthetic pathway lysine decarboxylase from the fire blight disease pathogen Erwinia amylovora | | 分子名称: | PYRIDOXAL-5'-PHOSPHATE, Putative decarboxylase involved in desferrioxamine biosynthesis | | 著者 | Salomone-Stagni, M, Bartho, J.D, Polsinelli, I, Bellini, D, Walsh, M.A, Demitri, N, Benini, S. | | 登録日 | 2017-06-01 | | 公開日 | 2018-02-28 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | A complete structural characterization of the desferrioxamine E biosynthetic pathway from the fire blight pathogen Erwinia amylovora.
J. Struct. Biol., 202, 2018
|
|
4E1O
 | | Human histidine decarboxylase complex with Histidine methyl ester (HME) | | 分子名称: | HISTIDINE-METHYL-ESTER, Histidine decarboxylase, PYRIDOXAL-5'-PHOSPHATE | | 著者 | Komori, H, Nitta, Y, Ueno, H, Higuchi, Y. | | 登録日 | 2012-03-06 | | 公開日 | 2012-07-18 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural study reveals that Ser-354 determines substrate specificity on human histidine decarboxylase
J.Biol.Chem., 287, 2012
|
|
2JIS
 | | Human cysteine sulfinic acid decarboxylase (CSAD) in complex with PLP. | | 分子名称: | CYSTEINE SULFINIC ACID DECARBOXYLASE, NITRATE ION, PYRIDOXAL-5'-PHOSPHATE | | 著者 | Collins, R, Moche, M, Arrowsmith, C, Berglund, H, Busam, R, Dahlgren, L.G, Edwards, A, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Hallberg, B.M, Johansson, I, Kallas, A, Karlberg, T, Kotenyova, T, Lehtio, L, Nordlund, P, Nyman, T, Ogg, D, Persson, C, Sagemark, J, Stenmark, P, Sundstrom, M, Thorsell, A.G, Tresaugues, L, van den Berg, S, Weigelt, J, Welin, M, Holmberg-Schiavone, L, Structural Genomics Consortium (SGC) | | 登録日 | 2007-06-30 | | 公開日 | 2007-08-28 | | 最終更新日 | 2015-04-22 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | The Crystal Structure of Human Cysteine Sulfinic Acid Decarboxylase (Csad)
To be Published
|
|
1XEY
 | | Crystal structure of the complex of Escherichia coli GADA with glutarate at 2.05 A resolution | | 分子名称: | ACETATE ION, GLUTARIC ACID, Glutamate decarboxylase alpha, ... | | 著者 | Dutyshev, D.I, Darii, E.L, Fomenkova, N.P, Pechik, I.V, Polyakov, K.M, Nikonov, S.V, Andreeva, N.S, Sukhareva, B.S. | | 登録日 | 2004-09-13 | | 公開日 | 2004-10-05 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Structure of Escherichia coli glutamate decarboxylase (GADalpha) in complex with glutarate at 2.05 angstroms resolution.
Acta Crystallogr.,Sect.D, 61, 2005
|
|
3F9T
 | |
8AYF
 | | Crystal structure of human Sphingosine-1-phosphate lyase 1 | | 分子名称: | ACETATE ION, GLYCEROL, Sphingosine-1-phosphate lyase 1 | | 著者 | Giardina, G, Catalano, F, Pampalone, G, Cellini, B. | | 登録日 | 2022-09-02 | | 公開日 | 2023-09-13 | | 最終更新日 | 2024-01-03 | | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | | 主引用文献 | Dual species sphingosine-1-phosphate lyase inhibitors to combine antifungal and anti-inflammatory activities in cystic fibrosis: a feasibility study.
Sci Rep, 13, 2023
|
|
8CMX
 | |
8OR9
 | |
8ORA
 | | Human holo aromatic L-amino acid decarboxylase (AADC) external aldimine with L-Dopa methylester | | 分子名称: | Dopa decarboxylase (Aromatic L-amino acid decarboxylase), PYRIDOXAL-5'-PHOSPHATE, TETRAETHYLENE GLYCOL, ... | | 著者 | Bisello, G, Perduca, M, Bertoldi, M. | | 登録日 | 2023-04-13 | | 公開日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Human aromatic amino acid decarboxylase is an asymmetric and flexible enzyme: Implication in aromatic amino acid decarboxylase deficiency.
Protein Sci., 32, 2023
|
|
6ZEK
 | | Crystal structure of mouse CSAD | | 分子名称: | CHLORIDE ION, COBALT (II) ION, Cysteine sulfinic acid decarboxylase, ... | | 著者 | Mahootchi, E, Raasakka, A, Haavik, J, Kursula, P. | | 登録日 | 2020-06-16 | | 公開日 | 2021-04-28 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structure and substrate specificity determinants of the taurine biosynthetic enzyme cysteine sulphinic acid decarboxylase.
J.Struct.Biol., 213, 2021
|
|
1JS3
 | | Crystal structure of dopa decarboxylase in complex with the inhibitor carbidopa | | 分子名称: | CARBIDOPA, DOPA decarboxylase, PYRIDOXAL-5'-PHOSPHATE, ... | | 著者 | Burkhard, P, Dominici, P, Borri-Voltattorni, C, Jansonius, J.N, Malashkevich, V.N. | | 登録日 | 2001-08-16 | | 公開日 | 2001-10-26 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Structural insight into Parkinson's disease treatment from drug-inhibited DOPA decarboxylase.
Nat.Struct.Biol., 8, 2001
|
|
1PMM
 | | Crystal structure of Escherichia coli GadB (low pH) | | 分子名称: | ACETIC ACID, Glutamate decarboxylase beta, PYRIDOXAL-5'-PHOSPHATE | | 著者 | Capitani, G, De Biase, D, Aurizi, C, Gut, H, Bossa, F, Grutter, M.G. | | 登録日 | 2003-06-11 | | 公開日 | 2004-02-17 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure and functional analysis of escherichia coli glutamate
decarboxylase
Embo J., 22, 2003
|
|
1PMO
 | | Crystal structure of Escherichia coli GadB (neutral pH) | | 分子名称: | (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Glutamate decarboxylase beta | | 著者 | Capitani, G, De Biase, D, Aurizi, C, Gut, H, Bossa, F, Grutter, M.G. | | 登録日 | 2003-06-11 | | 公開日 | 2004-02-17 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structure and functional analysis of escherichia coli glutamate
decarboxylase
Embo J., 22, 2003
|
|
1JS6
 | | Crystal Structure of DOPA decarboxylase | | 分子名称: | DOPA decarboxylase, PYRIDOXAL-5'-PHOSPHATE | | 著者 | Burkhard, P, Dominici, P, Borri-Voltattorni, C, Jansonius, J.N, Malashkevich, V.N. | | 登録日 | 2001-08-16 | | 公開日 | 2001-10-26 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural insight into Parkinson's disease treatment from drug-inhibited DOPA decarboxylase.
Nat.Struct.Biol., 8, 2001
|
|
7A0A
 | |
4OBV
 | | Ruminococcus gnavus tryptophan decarboxylase RUMGNA_01526 (alpha-FMT) | | 分子名称: | Pyridoxal-dependent decarboxylase domain protein, alpha-(fluoromethyl)-D-tryptophan, {5-hydroxy-4-[(1E)-4-(1H-indol-3-yl)-3-oxobut-1-en-1-yl]-6-methylpyridin-3-yl}methyl dihydrogen phosphate | | 著者 | Fraser, J.S, Van Benschoten, A.H. | | 登録日 | 2014-01-07 | | 公開日 | 2014-10-29 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.84 Å) | | 主引用文献 | Discovery and Characterization of Gut Microbiota Decarboxylases that Can Produce the Neurotransmitter Tryptamine.
Cell Host Microbe, 16, 2014
|
|
5EUE
 | | S1P Lyase Bacterial Surrogate bound to N-(2-((4-methoxy-2,5-dimethylbenzyl)amino)-1-phenylethyl)-5-methylisoxazole-3-carboxamide | | 分子名称: | PHOSPHATE ION, Putative sphingosine-1-phosphate lyase, ~{N}-[(1~{S})-2-[(4-methoxy-2,5-dimethyl-phenyl)methylamino]-1-phenyl-ethyl]-5-methyl-1,2-oxazole-3-carboxamide | | 著者 | Argiriadi, M.A, Banach, D, Radziejewska, E, Marchie, S, DiMauro, J, Dinges, J, Dominguez, E, Hutchins, C, Judge, R.A, Queeney, K, Wallace, G, Harris, C.M. | | 登録日 | 2015-11-18 | | 公開日 | 2016-03-16 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.83 Å) | | 主引用文献 | Creation of a S1P Lyase bacterial surrogate for structure-based drug design.
Bioorg.Med.Chem.Lett., 26, 2016
|
|
5EUD
 | | S1P Lyase Bacterial Surrogate bound to N-(1-(4-(3-hydroxyprop-1-yn-1-yl)phenyl)-2-((4-methoxy-2,5-dimethylbenzyl)amino)ethyl)-5-methylisoxazole-3-carboxamide | | 分子名称: | PHOSPHATE ION, Putative sphingosine-1-phosphate lyase, ~{N}-[(1~{S})-2-[(4-methoxy-2,5-dimethyl-phenyl)methylamino]-1-[4-(3-oxidanylprop-1-ynyl)phenyl]ethyl]-5-methyl-1,2-oxazole-3-carboxamide | | 著者 | Argiriadi, M.A, Banach, D, Radziejewska, E, Marchie, S, DiMauro, J, Dinges, J, Dominguez, E, Hutchins, C, Judge, R.A, Queeney, K, Wallace, G, Harris, C.M. | | 登録日 | 2015-11-18 | | 公開日 | 2016-03-16 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | | 主引用文献 | Creation of a S1P Lyase bacterial surrogate for structure-based drug design.
Bioorg.Med.Chem.Lett., 26, 2016
|
|
4OBU
 | |
3RBL
 | | Crystal structure of Human aromatic L-amino acid decarboxylase (AADC) in the apo form | | 分子名称: | CHLORIDE ION, aromatic L-amino acid decarboxylase | | 著者 | Giardina, G, Montioli, R, Gianni, S, Cellini, B, Paiardini, A, Borri Voltattorni, C, Cutruzzola, F. | | 登録日 | 2011-03-29 | | 公開日 | 2011-10-19 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (3.24 Å) | | 主引用文献 | Open conformation of human DOPA decarboxylase reveals the mechanism of PLP addition to Group II decarboxylases.
Proc.Natl.Acad.Sci.USA, 108, 2011
|
|
3RCH
 | | Crystal structure of Human aromatic L-amino acid decarboxylase (AADC) in the open conformation with LLP and PLP bound to Chain-A and Chain-B respectively | | 分子名称: | PYRIDOXAL-5'-PHOSPHATE, aromatic L-amino acid decarboxylase | | 著者 | Giardina, G, Montioli, R, Gianni, S, Cellini, B, Paiardini, A, Borri Voltattorni, C, Cutruzzola, F. | | 登録日 | 2011-03-31 | | 公開日 | 2011-10-19 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Open conformation of human DOPA decarboxylase reveals the mechanism of PLP addition to Group II decarboxylases.
Proc.Natl.Acad.Sci.USA, 108, 2011
|
|
7ERU
 | | Crystal structure of L-histidine decarboxylase (C57S mutant) from Photobacterium phosphoreum | | 分子名称: | Histidine decarboxylase | | 著者 | Oda, Y, Nakata, K, Yamaguchi, H, Kashiwagi, T, Miyano, H, Mizukoshi, T. | | 登録日 | 2021-05-07 | | 公開日 | 2022-02-16 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Structural insights into the enhanced thermostability of cysteine substitution mutants of L-histidine decarboxylase from Photobacterium phosphoreum.
J.Biochem., 171, 2022
|
|
7ERV
 | | Crystal structure of L-histidine decarboxylase (C57S/C101V/C282V mutant) from Photobacterium phosphoreum | | 分子名称: | Histidine decarboxylase, IMIDAZOLE | | 著者 | Oda, Y, Nakata, K, Yamaguchi, H, Kashiwagi, T, Miyano, H, Mizukoshi, T. | | 登録日 | 2021-05-07 | | 公開日 | 2022-02-16 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural insights into the enhanced thermostability of cysteine substitution mutants of L-histidine decarboxylase from Photobacterium phosphoreum.
J.Biochem., 171, 2022
|
|
