4OBV

Ruminococcus gnavus tryptophan decarboxylase RUMGNA_01526 (alpha-FMT)

Summary for 4OBV

Entry DOI	10.2210/pdb4obv/pdb
Related	4OBU
Descriptor	Pyridoxal-dependent decarboxylase domain protein, alpha-(fluoromethyl)-D-tryptophan, {5-hydroxy-4-[(1E)-4-(1H-indol-3-yl)-3-oxobut-1-en-1-yl]-6-methylpyridin-3-yl}methyl dihydrogen phosphate (3 entities in total)
Functional Keywords	type 1 plp-dependent, decarboxylase, lyase
Biological source	Ruminococcus gnavus
Total number of polymer chains	4
Total formula weight	222652.80
Authors	Fraser, J.S.,Van Benschoten, A.H. (deposition date: 2014-01-07, release date: 2014-10-29, Last modification date: 2024-02-28)
Primary citation	Williams, B.B.,Van Benschoten, A.H.,Cimermancic, P.,Donia, M.S.,Zimmermann, M.,Taketani, M.,Ishihara, A.,Kashyap, P.C.,Fraser, J.S.,Fischbach, M.A. Discovery and Characterization of Gut Microbiota Decarboxylases that Can Produce the Neurotransmitter Tryptamine. Cell Host Microbe, 16:495-503, 2014 Cited by PubMed: 25263219 DOI: 10.1016/j.chom.2014.09.001 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.84 Å)

Structure validation