PDB: 582 件ウェブページステータス検索Chemie searchBIRD

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7GQS	Crystal Structure of Werner helicase fragment 517-945 in complex with ADP 分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN, ... 著者 Classen, M, Benz, J, Brugger, D, Rudolph, M.G. 登録日 2023-10-19 公開日 2024-05-01 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.57 Å) 主引用文献 Chemoproteomic discovery of a covalent allosteric inhibitor of WRN helicase. Nature, 2024
7FSF	CRYSTAL STRUCTURE OF T. MARITIMA REVERSE GYRASE ACTIVE SITE VARIANT Y851F 分子名称: Reverse gyrase, ZINC ION 著者 Rasche, R, Kummel, D, Rudolph, M.G, Klostermeier, D. 登録日 2023-01-04 公開日 2023-05-10 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.77 Å) 主引用文献 Structure of reverse gyrase with a minimal latch that supports ATP-dependent positive supercoiling without specific interactions with the topoisomerase domain. Acta Crystallogr D Struct Biol, 79, 2023
7FSE	Crystal Structure of T. maritima reverse gyrase with a minimal latch 分子名称: CHLORIDE ION, DODECAETHYLENE GLYCOL, Reverse gyrase, ... 著者 Rasche, R, Kummel, D, Rudolph, M.G, Klostermeier, D. 登録日 2023-01-04 公開日 2023-05-10 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.89 Å) 主引用文献 Structure of reverse gyrase with a minimal latch that supports ATP-dependent positive supercoiling without specific interactions with the topoisomerase domain. Acta Crystallogr D Struct Biol, 79, 2023
7EVO	The cryo-EM structure of the human 17S U2 snRNP 分子名称: HIV Tat-specific factor 1, PHD finger-like domain-containing protein 5A, RNA helicase, ... 著者 Zhang, X, Zhan, X, Shi, Y. 登録日 2021-05-21 公開日 2022-08-03 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (2.5 Å) 主引用文献 Structural insights into branch site proofreading by human spliceosome. Nat.Struct.Mol.Biol., 2024
7EVN	The cryo-EM structure of the DDX42-SF3b complex 分子名称: ATP-dependent RNA helicase DDX42, PHD finger-like domain-containing protein 5A, Splicing factor 3B subunit 1, ... 著者 Zhang, X, Zhan, X, Shi, Y. 登録日 2021-05-21 公開日 2022-08-03 最終更新日 2024-01-17 実験手法 ELECTRON MICROSCOPY (2.6 Å) 主引用文献 Structural insights into branch site proofreading by human spliceosome Nat.Struct.Mol.Biol., 2024
7DVQ	Cryo-EM Structure of the Activated Human Minor Spliceosome (minor Bact Complex) 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, 5'-O-[(S)-hydroxy{[(R)-hydroxy{[(S)-hydroxy(methoxy)phosphoryl]oxy}phosphoryl]oxy}phosphoryl]guanosine, Armadillo repeat-containing protein 7, ... 著者 Bai, R, Wan, R, Wang, L, Xu, K, Zhang, Q, Lei, J, Shi, Y. 登録日 2021-01-14 公開日 2021-03-31 実験手法 ELECTRON MICROSCOPY (2.89 Å) 主引用文献 Structure of the activated human minor spliceosome. Science, 371, 2021
7DTK	Crystal structure of the RecA1 domain of RNA helicase CGH-1 in C. elegans 分子名称: ATP-dependent RNA helicase cgh-1, GLYCEROL 著者 Hong, J.J, Lv, M.Q, Zhang, Y. 登録日 2021-01-05 公開日 2021-03-17 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.849 Å) 主引用文献 Structural and biochemical insights into the recognition of RNA helicase CGH-1 by CAR-1 in C. elegans. Biochem.Biophys.Res.Commun., 549, 2021
7DDX	Crystal structure of KANK1 S1179F mutant in complex wtih eIF4A1 分子名称: Eukaryotic initiation factor 4A-I, GLYCEROL, KN motif and ankyrin repeat domains 1, ... 著者 Pan, W, Xu, Y, Wei, Z. 登録日 2020-10-30 公開日 2021-09-08 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Nephrotic-syndrome-associated mutation of KANK2 induces pathologic binding competition with physiological interactor KIF21A. J.Biol.Chem., 297, 2021
7DD3	Cryo-EM structure of the pre-mRNA-loaded DEAH-box ATPase/helicase Prp2 in complex with Spp2 分子名称: PRP2 isoform 1, Pre-mRNA-splicing factor SPP2, pre-mRNA 著者 Bai, R, Wan, R, Yan, C, Qi, J, Zhang, P, Lei, J, Shi, Y. 登録日 2020-10-27 公開日 2021-01-06 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Mechanism of spliceosome remodeling by the ATPase/helicase Prp2 and its coactivator Spp2. Science, 371, 2021
7DCR	cryo-EM structure of the DEAH-box helicase Prp2 in complex with its coactivator Spp2 分子名称: PRP2 isoform 1, Pre-mRNA-splicing factor SPP2 著者 Bai, R, Wan, R, Yan, C, Jia, Q, Zhang, P, Lei, J, Shi, Y. 登録日 2020-10-26 公開日 2021-01-06 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.15 Å) 主引用文献 Mechanism of spliceosome remodeling by the ATPase/helicase Prp2 and its coactivator Spp2. Science, 371, 2021
7DCQ	cryo-EM structure of the DEAH-box helicase Prp2 分子名称: PRP2 isoform 1 著者 Bai, R, Wan, R, Yan, C, Jia, Q, Zhang, P, Lei, J, Shi, Y. 登録日 2020-10-26 公開日 2021-01-06 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Mechanism of spliceosome remodeling by the ATPase/helicase Prp2 and its coactivator Spp2. Science, 371, 2021
7DCP	cryo-EM structure of the DEAH-box helicase Prp2 and coactivator Spp2 分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PRP2 isoform 1, ... 著者 Bai, R, Wan, R, Yan, C, Jia, Q, Zhang, P, Lei, J, Shi, Y. 登録日 2020-10-26 公開日 2021-01-06 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.15 Å) 主引用文献 Mechanism of spliceosome remodeling by the ATPase/helicase Prp2 and its coactivator Spp2. Science, 371, 2021
7DCO	Cryo-EM structure of the activated spliceosome (Bact complex) at an atomic resolution of 2.5 angstrom 分子名称: BJ4_G0014900.mRNA.1.CDS.1, BJ4_G0027490.mRNA.1.CDS.1, BJ4_G0037700.mRNA.1.CDS.1, ... 著者 Bai, R, Wan, R, Yan, C, Qi, J, Zhang, P, Lei, J, Shi, Y. 登録日 2020-10-26 公開日 2021-03-17 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (2.5 Å) 主引用文献 Mechanism of spliceosome remodeling by the ATPase/helicase Prp2 and its coactivator Spp2. Science, 371, 2021
7D63	Cryo-EM structure of 90S preribosome with inactive Utp24 (state C) 分子名称: 13 kDa ribonucleoprotein-associated protein, 18S rRNA, 40S ribosomal protein S1-A, ... 著者 Du, Y, Zhang, J, An, W, Ye, K. 登録日 2020-09-29 公開日 2021-10-06 実験手法 ELECTRON MICROSCOPY (12.3 Å) 主引用文献 Cryo-EM structure of 90S preribosome with inactive Utp24 (state C) To Be Published
7D5T	Cryo-EM structure of 90S preribosome with inactive Utp24 (state F1) 分子名称: 13 kDa ribonucleoprotein-associated protein, 18S rRNA, 40S ribosomal protein S1-A, ... 著者 Du, Y, Zhang, J, An, W, Ye, K. 登録日 2020-09-28 公開日 2021-10-06 実験手法 ELECTRON MICROSCOPY (6 Å) 主引用文献 Cryo-EM structure of 90S preribosome with inactive Utp24 (state F1) To Be Published
7D4I	Cryo-EM structure of 90S small ribosomal precursors complex with the DEAH-box RNA helicase Dhr1 (State F) 分子名称: 13 kDa ribonucleoprotein-associated protein, 18S rRNA, 40S ribosomal protein S1-A, ... 著者 Du, Y, Zhang, J, An, W, Ye, K. 登録日 2020-09-24 公開日 2021-10-06 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Cryo-EM structure of 90S small ribosomal precursors complex with Dhr1 To Be Published
7BDL	Human Brr2 Helicase Region in complex with C-tail deleted Jab1 and mant-ADP 分子名称: MAGNESIUM ION, Pre-mRNA-processing-splicing factor 8, U5 small nuclear ribonucleoprotein 200 kDa helicase, ... 著者 Vester, K, Santos, K.F, Absmeier, E, Wahl, M.C. 登録日 2020-12-21 公開日 2021-06-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.69 Å) 主引用文献 Long-range allostery mediates cooperative adenine nucleotide binding by the Ski2-like RNA helicase Brr2. J.Biol.Chem., 297, 2021
7BDK	Human Brr2 Helicase Region in complex with C-tail deleted Jab1 and ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Pre-mRNA-processing-splicing factor 8, ... 著者 Vester, K, Santos, K.F, Absmeier, E, Wahl, M.C. 登録日 2020-12-21 公開日 2021-06-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.52 Å) 主引用文献 Long-range allostery mediates cooperative adenine nucleotide binding by the Ski2-like RNA helicase Brr2. J.Biol.Chem., 297, 2021
7BDJ	Human Brr2 Helicase Region in complex with C-tail deleted Jab1 and mant-ATPgammaS 分子名称: MAGNESIUM ION, Pre-mRNA-processing-splicing factor 8, U5 small nuclear ribonucleoprotein 200 kDa helicase, ... 著者 Vester, K, Santos, K.F, Absmeier, E, Wahl, M.C. 登録日 2020-12-21 公開日 2021-06-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.59 Å) 主引用文献 Long-range allostery mediates cooperative adenine nucleotide binding by the Ski2-like RNA helicase Brr2. J.Biol.Chem., 297, 2021
7BDI	Human Brr2 Helicase Region in complex with C-tail deleted Jab1 and ATPgammaS 分子名称: MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Pre-mRNA-processing-splicing factor 8, ... 著者 Vester, K, Santos, K.F, Absmeier, E, Wahl, M.C. 登録日 2020-12-21 公開日 2021-06-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Long-range allostery mediates cooperative adenine nucleotide binding by the Ski2-like RNA helicase Brr2. J.Biol.Chem., 297, 2021
7B9V	Yeast C complex spliceosome at 2.8 Angstrom resolution with Prp18/Slu7 bound 分子名称: 5' exon of UBC4 mRNA, BJ4_G0027490.mRNA.1.CDS.1, BJ4_G0054360.mRNA.1.CDS.1, ... 著者 Wilkinson, M.E, Fica, S.M, Galej, W.P, Nagai, K. 登録日 2020-12-14 公開日 2021-03-10 最終更新日 2021-04-14 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Structural basis for conformational equilibrium of the catalytic spliceosome. Mol.Cell, 81, 2021
7AUD	Structure of an engineered helicase domain construct for human Bloom syndrome protein (BLM) 分子名称: ADENOSINE-5'-DIPHOSPHATE, Bloom syndrome protein,Bloom syndrome protein, DNA (5'-D(*GP*TP*AP*CP*CP*CP*GP*AP*TP*GP*TP*GP*T)-3'), ... 著者 Chen, X, Oliver, A.W. 登録日 2020-11-02 公開日 2020-12-16 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.96 Å) 主引用文献 Uncovering an allosteric mode of action for a selective inhibitor of human Bloom syndrome protein. Elife, 10, 2021
7AUC	Crystal structure of an engineered helicase domain construct for human Bloom syndrome protein (BLM) 分子名称: 1,2-ETHANEDIOL, ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, ... 著者 Chen, X, Oliver, A.W. 登録日 2020-11-02 公開日 2020-12-16 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.53 Å) 主引用文献 Uncovering an allosteric mode of action for a selective inhibitor of human Bloom syndrome protein. Elife, 10, 2021
7ASK	43S preinitiation complex from Trypanosoma cruzi with the kDDX60 helicase bound with ATP 分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, kDDX60 著者 Bochler, A, Brito Querido, J, Prilepskaja, T, Soufari, H, Del Cistia, M.L, Kuhn, L, Rimoldi Ribeiro, A, Valasek, L.S, Hashem, Y. 登録日 2020-10-27 公開日 2021-04-14 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (4.3 Å) 主引用文献 Structural Differences in Translation Initiation between Pathogenic Trypanosomatids and Their Mammalian Hosts. Cell Rep, 33, 2020
7ASE	43S preinitiation complex from Trypanosoma cruzi with the kDDX60 helicase 分子名称: 18S, 40S ribosomal protein S10, putative, ... 著者 Bochler, A, Brito Querido, J, Prilepskaja, T, Soufari, H, Del Cistia, M.L, Kuhn, L, Rimoldi Ribeiro, A, Valasek, L.S, Hashem, Y. 登録日 2020-10-27 公開日 2021-04-14 最終更新日 2021-04-21 実験手法 ELECTRON MICROSCOPY (3.33 Å) 主引用文献 Structural Differences in Translation Initiation between Pathogenic Trypanosomatids and Their Mammalian Hosts. Cell Rep, 33, 2020

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