7BDL

Human Brr2 Helicase Region in complex with C-tail deleted Jab1 and mant-ADP

Summary for 7BDL

Entry DOI	10.2210/pdb7bdl/pdb
Related	7BDI 7BDJ 7BDK
Descriptor	U5 small nuclear ribonucleoprotein 200 kDa helicase, Pre-mRNA-processing-splicing factor 8, [(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-4-oxidanyl-2-[[oxidanyl(phosphonooxy)phosphoryl]oxymethyl]oxolan-3-yl] 2-(methylamino)benzoate, ... (5 entities in total)
Functional Keywords	rnp remodeling, pre-mrna splicing, spliceosome catalytic activation, dexd/h-box rna helicase, rna and atp binding, nucleus, hydrolase
Biological source	Homo sapiens (Human) More
Total number of polymer chains	2
Total formula weight	230969.19
Authors	Vester, K.,Santos, K.F.,Absmeier, E.,Wahl, M.C. (deposition date: 2020-12-21, release date: 2021-06-09, Last modification date: 2024-01-31)
Primary citation	Absmeier, E.,Vester, K.,Ghane, T.,Burakovskiy, D.,Milon, P.,Imhof, P.,Rodnina, M.V.,Santos, K.F.,Wahl, M.C. Long-range allostery mediates cooperative adenine nucleotide binding by the Ski2-like RNA helicase Brr2. J.Biol.Chem., 297:100829-100829, 2021 Cited by PubMed: 34048711 DOI: 10.1016/j.jbc.2021.100829 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.69 Å)

Structure validation