4H1G
 
 | | Structure of Candida albicans Kar3 motor domain fused to maltose-binding protein | | 分子名称: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Allingham, J.A, Duan, D, Delorme, C, Joshi, M. | | 登録日 | 2012-09-10 | | 公開日 | 2012-10-10 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Crystal structure of the Candida albicans Kar3 kinesin motor domain fused to maltose-binding protein.
Biochem.Biophys.Res.Commun., 428, 2012
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4BBG
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4HNA
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3ZCW
 | | Eg5 - New allosteric binding site | | 分子名称: | (2E)-2-(3-fluoranyl-4-methoxy-phenyl)imino-1-[[2-(trifluoromethyl)phenyl]methyl]-3H-benzimidazole-5-carboxylic acid, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ADENOSINE-5'-DIPHOSPHATE, ... | | 著者 | Ulaganathan, V, Talapatra, S.K, Kozielski, F, Pannifer, A.D. | | 登録日 | 2012-11-23 | | 公開日 | 2013-01-23 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.691 Å) | | 主引用文献 | Structural Insights Into a Unique Inhibitor Binding Pocket in Kinesin Spindle Protein.
J.Am.Chem.Soc., 135, 2013
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3ZFD
 | | Crystal Structure of the Kif4 Motor Domain Complexed With Mg-AMPPNP | | 分子名称: | CHROMOSOME-ASSOCIATED KINESIN KIF4, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | | 著者 | Chang, Q, Nitta, R, Inoue, S, Hirokawa, N. | | 登録日 | 2012-12-11 | | 公開日 | 2013-03-20 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | | 主引用文献 | Structural Basis for the ATP-Induced Isomerization of Kinesin.
J.Mol.Biol., 425, 2013
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3ZFC
 | | Crystal Structure of the Kif4 Motor Domain Complexed With Mg-AMPPNP | | 分子名称: | CHROMOSOME-ASSOCIATED KINESIN KIF4, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | | 著者 | Chang, Q, Nitta, R, Inoue, S, Hirokawa, N. | | 登録日 | 2012-12-11 | | 公開日 | 2013-03-20 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural Basis for the ATP-Induced Isomerization of Kinesin.
J.Mol.Biol., 425, 2013
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3J2U
 | | Kinesin-13 KLP10A HD in complex with CS-tubulin and a microtubule | | 分子名称: | Kinesin-like protein Klp10A, Tubulin alpha-1A chain, Tubulin beta-2B chain | | 著者 | Asenjo, A.B, Chatterjee, C, Tan, D, DePaoli, V, Rice, W.J, Diaz-Avalos, R, Silvestry, M, Sosa, H. | | 登録日 | 2013-01-10 | | 公開日 | 2013-03-06 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (10.8 Å) | | 主引用文献 | Structural model for tubulin recognition and deformation by Kinesin-13 microtubule depolymerases.
Cell Rep, 3, 2013
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4BN2
 | | The crystal structure of kinesin-like protein KIF15 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, KINESIN-LIKE PROTEIN KIF15, MAGNESIUM ION | | 著者 | Klejnot, M, Falnikar, A, Ulaganathan, V, Cross, R, Baas, P, Kozielski, F. | | 登録日 | 2013-05-13 | | 公開日 | 2014-01-15 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.695 Å) | | 主引用文献 | The Crystal Structure and Biochemical Characterization of Kif15: A Bifunctional Molecular Motor Involved in Bipolar Spindle Formation and Neuronal Development
Acta Crystallogr.,Sect.D, 70, 2014
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4LNU
 | | Nucleotide-free kinesin motor domain in complex with tubulin and a DARPin | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Designed ankyrin repeat protein (DARPIN) D1, GLYCEROL, ... | | 著者 | Cao, L, Gigant, B, Knossow, M. | | 登録日 | 2013-07-12 | | 公開日 | 2014-12-03 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | | 主引用文献 | The structure of apo-kinesin bound to tubulin links the nucleotide cycle to movement
Nat Commun, 5, 2014
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4BXN
 | | Eg5(WT) complex | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, CADMIUM ION, CHLORIDE ION, ... | | 著者 | Talapatra, S.K, Anthony, N.G, Mackay, S.P, Kozielski, F. | | 登録日 | 2013-07-15 | | 公開日 | 2013-07-31 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.793 Å) | | 主引用文献 | The Mitotic Kinesin Eg5 Overcomes Inhibition to the Phase I/II Clinical Candidate Sb743921 by an Allosteric Resistance Mechanism.
J.Med.Chem., 56, 2013
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4CK6
 | | Pseudo-atomic model of microtubule-bound human kinesin-5 motor domain in the ADP.AlFx state, based on cryo-electron microscopy experiment. | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, GUANOSINE-5'-DIPHOSPHATE, ... | | 著者 | Goulet, A, Major, J, Jun, Y, Gross, S, Rosenfeld, S, Moores, C. | | 登録日 | 2013-12-30 | | 公開日 | 2014-02-05 | | 最終更新日 | 2017-08-30 | | 実験手法 | ELECTRON MICROSCOPY (9.2 Å) | | 主引用文献 | Comprehensive Structural Model of the Mechanochemical Cycle of a Mitotic Motor Highlights Molecular Adaptations in the Kinesin Family.
Proc.Natl.Acad.Sci.USA, 111, 2014
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4CK7
 | | Pseudo-atomic model of microtubule-bound human kinesin-5 motor domain in presence of adp.alfx (NECK-LINKER IN ITS DISCONNECTED CONFORMATION, based on cryo-electron microscopy experiment | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, GUANOSINE-5'-DIPHOSPHATE, ... | | 著者 | Goulet, A, Major, J, Jun, Y, Gross, S, Rosenfeld, S, Moores, C. | | 登録日 | 2013-12-30 | | 公開日 | 2014-02-05 | | 最終更新日 | 2017-08-30 | | 実験手法 | ELECTRON MICROSCOPY (9.2 Å) | | 主引用文献 | Comprehensive Structural Model of the Mechanochemical Cycle of a Mitotic Motor Highlights Molecular Adaptations in the Kinesin Family.
Proc.Natl.Acad.Sci.USA, 111, 2014
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4CK5
 | | Pseudo-atomic model of microtubule-bound human kinesin-5 motor domain in the ADP state, based on cryo-electron microscopy experiment. | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Goulet, A, Major, J, Jun, Y, Gross, S, Rosenfeld, S, Moores, C. | | 登録日 | 2013-12-30 | | 公開日 | 2014-02-05 | | 最終更新日 | 2017-08-30 | | 実験手法 | ELECTRON MICROSCOPY (10 Å) | | 主引用文献 | Comprehensive Structural Model of the Mechanochemical Cycle of a Mitotic Motor Highlights Molecular Adaptations in the Kinesin Family.
Proc.Natl.Acad.Sci.USA, 111, 2014
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3WPN
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4OZQ
 | | Crystal structure of the mouse Kif14 motor domain | | 分子名称: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, Chimera of Maltose-binding periplasmic protein and Kinesin family member 14 protein | | 著者 | Arora, K, Talje, L, Asenjo, A.B, Andersen, P, Atchia, K, Joshi, M, Sosa, H, Kwok, B.H, Allingham, J.S. | | 登録日 | 2014-02-18 | | 公開日 | 2014-07-09 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | | 主引用文献 | KIF14 binds tightly to microtubules and adopts a rigor-like conformation.
J.Mol.Biol., 426, 2014
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3J6H
 | | Nucleotide-free Kinesin motor domain complexed with GMPCPP-microtubule | | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, Kinesin heavy chain isoform 5C, MAGNESIUM ION, ... | | 著者 | Morikawa, M, Yajima, H, Nitta, R, Inoue, S, Ogura, T, Sato, C, Hirokawa, N. | | 登録日 | 2014-02-21 | | 公開日 | 2015-04-01 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (8.1 Å) | | 主引用文献 | X-ray and Cryo-EM structures reveal mutual conformational changes of Kinesin and GTP-state microtubules upon binding
Embo J., 2015
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3WRD
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4UBF
 | | HsMCAK motor domain complex | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Kinesin-like protein KIF2C, MAGNESIUM ION | | 著者 | Welburn, J.P.I, Talapatra, S.K. | | 登録日 | 2014-08-12 | | 公開日 | 2015-05-06 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | The C-terminal region of the motor protein MCAK controls its structure and activity through a conformational switch.
Elife, 4, 2015
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4UXS
 | | Conserved mechanisms of microtubule-stimulated ADP release, ATP binding, and force generation in transport kinesins | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, KINESIN-3 MOTOR DOMAIN, ... | | 著者 | Atherton, J, Farabella, I, Yu, I.M, Rosenfeld, S.S, Houdusse, A, Topf, M, Moores, C. | | 登録日 | 2014-08-27 | | 公開日 | 2014-09-24 | | 最終更新日 | 2017-08-23 | | 実験手法 | ELECTRON MICROSCOPY (7 Å) | | 主引用文献 | Conserved Mechanisms of Microtubule-Stimulated Adp Release, ATP Binding, and Force Generation in Transport Kinesins.
Elife, 3, 2014
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4UXR
 | | Conserved mechanisms of microtubule-stimulated ADP release, ATP binding, and force generation in transport kinesins | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Atherton, J, Farabella, I, Yu, I.M, Rosenfeld, S.S, Houdusse, A, Topf, M, Moores, C. | | 登録日 | 2014-08-27 | | 公開日 | 2014-09-24 | | 最終更新日 | 2017-08-23 | | 実験手法 | ELECTRON MICROSCOPY (7 Å) | | 主引用文献 | Conserved Mechanisms of Microtubule-Stimulated Adp Release, ATP Binding, and Force Generation in Transport Kinesins.
Elife, 3, 2014
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4UY0
 | | Conserved mechanisms of microtubule-stimulated ADP release, ATP binding, and force generation in transport kinesins | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Atherton, J, Farabella, I, Yu, I.M, Rosenfeld, S.S, Houdusse, A, Topf, M, Moores, C. | | 登録日 | 2014-08-27 | | 公開日 | 2014-09-24 | | 最終更新日 | 2017-08-30 | | 実験手法 | ELECTRON MICROSCOPY (7.7 Å) | | 主引用文献 | Conserved Mechanisms of Microtubule-Stimulated Adp Release, ATP Binding, and Force Generation in Transport Kinesins.
Elife, 3, 2014
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4UXO
 | | Conserved mechanisms of microtubule-stimulated ADP release, ATP binding, and force generation in transport kinesins | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, KINESIN-3 MOTOR DOMAIN, ... | | 著者 | Atherton, J, Farabella, I, Yu, I.M, Rosenfeld, S.S, Houdusse, A, Topf, M, Moores, C. | | 登録日 | 2014-08-27 | | 公開日 | 2014-09-24 | | 最終更新日 | 2018-04-04 | | 実験手法 | ELECTRON MICROSCOPY (6.3 Å) | | 主引用文献 | Conserved Mechanisms of Microtubule-Stimulated Adp Release, ATP Binding, and Force Generation in Transport Kinesins.
Elife, 3, 2014
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4UXP
 | | Conserved mechanisms of microtubule-stimulated ADP release, ATP binding, and force generation in transport kinesins | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, KINESIN-3 MOTOR DOMAIN, ... | | 著者 | Atherton, J, Farabella, I, Yu, I.M, Rosenfeld, S.S, Houdusse, A, Topf, M, Moores, C. | | 登録日 | 2014-08-27 | | 公開日 | 2014-09-24 | | 最終更新日 | 2017-08-23 | | 実験手法 | ELECTRON MICROSCOPY (6.3 Å) | | 主引用文献 | Conserved Mechanisms of Microtubule-Stimulated Adp Release, ATP Binding, and Force Generation in Transport Kinesins.
Elife, 3, 2014
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4UXY
 | | Conserved mechanisms of microtubule-stimulated ADP release, ATP binding, and force generation in transport kinesins | | 分子名称: | ALPHA TUBULIN, BETA TUBULIN, GUANOSINE-5'-DIPHOSPHATE, ... | | 著者 | Atherton, J, Farabella, I, Yu, I.M, Rosenfeld, S.S, Houdusse, A, Topf, M, Moores, C. | | 登録日 | 2014-08-27 | | 公開日 | 2014-09-24 | | 最終更新日 | 2017-08-30 | | 実験手法 | ELECTRON MICROSCOPY (6.5 Å) | | 主引用文献 | Conserved Mechanisms of Microtubule-Stimulated Adp Release, ATP Binding, and Force Generation in Transport Kinesins.
Elife, 3, 2014
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4UXT
 | | Conserved mechanisms of microtubule-stimulated ADP release, ATP binding, and force generation in transport kinesins | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, KINESIN HEAVY CHAIN ISOFORM 5A, ... | | 著者 | Atherton, J, Farabella, I, Yu, I.M, Rosenfeld, S.S, Houdusse, A, Topf, M, Moores, C. | | 登録日 | 2014-08-27 | | 公開日 | 2014-09-24 | | 最終更新日 | 2017-08-23 | | 実験手法 | ELECTRON MICROSCOPY (7.4 Å) | | 主引用文献 | Conserved Mechanisms of Microtubule-Stimulated Adp Release, ATP Binding, and Force Generation in Transport Kinesins.
Elife, 3, 2014
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