4CK5
Pseudo-atomic model of microtubule-bound human kinesin-5 motor domain in the ADP state, based on cryo-electron microscopy experiment.
Summary for 4CK5
| Entry DOI | 10.2210/pdb4ck5/pdb |
| Related | 4CK6 4CK7 |
| EMDB information | 2537 |
| Descriptor | TUBULIN ALPHA-1D CHAIN, TUBULIN BETA-2B CHAIN, KINESIN-LIKE PROTEIN KIF11, ... (8 entities in total) |
| Functional Keywords | motor protein, kinesins, microtubules, mitosis, mechanochemistry |
| Biological source | HOMO SAPIENS (HUMAN) More |
| Cellular location | Cytoplasm, cytoskeleton : Q2HJ86 Q6B856 Cytoplasm : P52732 |
| Total number of polymer chains | 3 |
| Total formula weight | 144089.02 |
| Authors | Goulet, A.,Major, J.,Jun, Y.,Gross, S.,Rosenfeld, S.,Moores, C. (deposition date: 2013-12-30, release date: 2014-02-05, Last modification date: 2017-08-30) |
| Primary citation | Goulet, A.,Major, J.,Jun, Y.,Gross, S.P.,Rosenfeld, S.S.,Moores, C.A. Comprehensive Structural Model of the Mechanochemical Cycle of a Mitotic Motor Highlights Molecular Adaptations in the Kinesin Family. Proc.Natl.Acad.Sci.USA, 111:1837-, 2014 Cited by PubMed: 24449904DOI: 10.1073/PNAS.1319848111 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (10 Å) |
Structure validation
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