4CK7

Pseudo-atomic model of microtubule-bound human kinesin-5 motor domain in presence of adp.alfx (NECK-LINKER IN ITS DISCONNECTED CONFORMATION, based on cryo-electron microscopy experiment

Summary for 4CK7

Entry DOI	10.2210/pdb4ck7/pdb
Related	4CK5 4CK6
EMDB information	2533
Descriptor	TUBULIN ALPHA-1D CHAIN, TUBULIN BETA-2B CHAIN, KINESIN-LIKE PROTEIN KIF11, ... (9 entities in total)
Functional Keywords	motor protein, kinesins, microtubules, mitosis, mechanochemistry
Biological source	HOMO SAPIENS (HUMAN) More
Cellular location	Cytoplasm, cytoskeleton : Q2HJ86 Q6B856 Cytoplasm : P52732
Total number of polymer chains	3
Total formula weight	144197.30
Authors	Goulet, A.,Major, J.,Jun, Y.,Gross, S.,Rosenfeld, S.,Moores, C. (deposition date: 2013-12-30, release date: 2014-02-05, Last modification date: 2024-05-08)
Primary citation	Goulet, A.,Major, J.,Jun, Y.,Gross, S.P.,Rosenfeld, S.S.,Moores, C.A. Comprehensive Structural Model of the Mechanochemical Cycle of a Mitotic Motor Highlights Molecular Adaptations in the Kinesin Family. Proc.Natl.Acad.Sci.USA, 111:1837-, 2014 Cited by PubMed: 24449904 DOI: 10.1073/PNAS.1319848111 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (9.2 Å)

Structure validation