PDB: 106 件ウェブページステータス検索Chemie searchBIRD

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3T4A	Structure of a truncated form of Staphylococcal Complement Inhibitor B bound to human C3c at 3.4 Angstrom resolution 分子名称: Complement C3 beta chain, Complement C3c alpha' chain fragment 1, Complement C3c alpha' chain fragment 2, ... 著者 Garcia, B.L, Geisbrecht, B.V, Summers, B.J. 登録日 2011-07-25 公開日 2011-11-23 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Diversity in the C3b Convertase Contact Residues and Tertiary Structures of the Staphylococcal Complement Inhibitor (SCIN) Protein Family. J.Biol.Chem., 287, 2012
6RQJ	Structure of human complement C5 complexed with tick inhibitors OmCI, RaCI1 and CirpT1 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C5, Complement inhibitor, ... 著者 Reichhardt, M.P, Johnson, S, Lea, S.M. 登録日 2019-05-15 公開日 2020-01-08 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 An inhibitor of complement C5 provides structural insights into activation. Proc.Natl.Acad.Sci.USA, 117, 2020
8CEM	Structure of bovine native C3, re-refinement 分子名称: Complement C3 alpha chain, Complement C3 beta chain, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose 著者 Andersen, G.R, Fredslund, F. 登録日 2023-02-02 公開日 2023-04-05 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 The structure of bovine complement component 3 reveals the basis for thioester function. J Mol Biol, 361, 2006
7QIV	Structure of human C3b in complex with the EWE nanobody 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C3 beta chain, Complement C3b alpha' chain, ... 著者 Pedersen, H, Andersen, G.R. 登録日 2021-12-16 公開日 2022-02-16 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structure-Guided Engineering of a Complement Component C3-Binding Nanobody Improves Specificity and Adds Cofactor Activity. Front Immunol, 13, 2022
8CML	Cryo-EM structure of complement C5 in complex with nanobodies UNbC5-1 and UNbC5-2 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C5 alpha chain, Complement C5 beta chain, ... 著者 De la O Becerra, K.I, Gros, P. 登録日 2023-02-20 公開日 2023-09-27 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Inhibition of cleavage of human complement component C5 and the R885H C5 variant by two distinct high affinity anti-C5 nanobodies. J.Biol.Chem., 299, 2023
3FRP	Crystal Structure of Cobra Venom Factor, a Co-factor for C3- and C5 convertase CVFBb 分子名称: CALCIUM ION, Cobra venom factor alpha chain, Cobra venom factor beta chain, ... 著者 Krishnan, V, Narayana, S.V.L. 登録日 2009-01-08 公開日 2009-04-28 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.61 Å) 主引用文献 The Crystal Structure of Cobra Venom Factor, a Cofactor for C3- and C5-Convertase CVFBb. Structure, 17, 2009
7S63	Native-form oocyte/egg Alpha-2-Macroglobulin (A2Moo) tetramer 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha 2-Macroglobulin 著者 Arimura, Y, Funabiki, H. 登録日 2021-09-13 公開日 2022-01-05 最終更新日 2022-01-19 実験手法 ELECTRON MICROSCOPY (4.12 Å) 主引用文献 Structural Mechanics of the Alpha-2-Macroglobulin Transformation. J.Mol.Biol., 434, 2021
7S62	Locally refined protomer structure of native-form oocyte/egg Alpha-2-Macroglobulin (A2Moo) tetramer 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha 2-macroglobulin 著者 Arimura, Y, Funabiki, H. 登録日 2021-09-12 公開日 2022-01-05 最終更新日 2022-01-19 実験手法 ELECTRON MICROSCOPY (3.65 Å) 主引用文献 Structural Mechanics of the Alpha-2-Macroglobulin Transformation. J.Mol.Biol., 434, 2021
7S64	Intermediate-form oocyte/egg Alpha-2-Macroglobulin (A2Moo) tetramer 分子名称: Alpha 2-macroglobulin 著者 Arimura, Y, Funabiki, H. 登録日 2021-09-13 公開日 2022-01-05 最終更新日 2022-01-19 実験手法 ELECTRON MICROSCOPY (6.43 Å) 主引用文献 Structural Mechanics of the Alpha-2-Macroglobulin Transformation. J.Mol.Biol., 434, 2021
6TAV	Crystal structure of endopeptidase-induced alpha2-macroglobulin 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-2-macroglobulin, ... 著者 Gomis-Ruth, F.X, Duquerroy, S, Trapani, S, Marrero, A, Goulas, T, Guevara, T, Andersen, G.A, Sottrup-Jensen, L, Navaza, J. 登録日 2019-10-30 公開日 2021-05-12 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (4.2 Å) 主引用文献 Cryo-EM structures shows the mechanistic basis of pan-peptidase inhibition by human alpha2-macroglobulin Proc.Natl.Acad.Sci.USA, 2022
3G6J	C3b in complex with a C3b specific Fab 分子名称: CALCIUM ION, Complement C3 alpha chain, Complement C3 beta chain, ... 著者 Wiesmann, C. 登録日 2009-02-06 公開日 2009-03-10 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structural and Functional Analysis of a C3b-specific Antibody That Selectively Inhibits the Alternative Pathway of Complement J.Biol.Chem., 284, 2009
4RTD	Escherichia coli alpha-2-macroglobulin activated by porcine elastase 分子名称: Uncharacterized lipoprotein YfhM 著者 Fyfe, C.D, Grinter, R, Roszak, A.W, Josts, I, Cogdell, R.J, Walker, D. 登録日 2014-11-14 公開日 2015-07-15 最終更新日 2015-07-29 実験手法 X-RAY DIFFRACTION (3.65 Å) 主引用文献 Structure of protease-cleaved Escherichia coli alpha-2-macroglobulin reveals a putative mechanism of conformational activation for protease entrapment. Acta Crystallogr.,Sect.D, 71, 2015
4U48	Crystal structure of Salmonella alpha-2-macroglobulin 分子名称: Putative inner membrane lipoprotein 著者 Wong, S.G, Dessen, A. 登録日 2014-07-23 公開日 2014-09-17 最終更新日 2019-02-20 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Structure of a bacterial alpha 2-macroglobulin reveals mimicry of eukaryotic innate immunity. Nat Commun, 5, 2014
4U4J	Crystal structure of Salmonella alpha-2-macroglobulin mutant Y1175G 分子名称: Putative inner membrane lipoprotein 著者 Wong, S.G, Dessen, A. 登録日 2014-07-23 公開日 2014-09-17 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structure of a bacterial alpha 2-macroglobulin reveals mimicry of eukaryotic innate immunity. Nat Commun, 5, 2014
4U59	Crystal structure of Salmonella alpha-2-macroglobulin reacted with methylamine 分子名称: alpha-2-macroglobulin 著者 Wong, S.G, Dessen, A. 登録日 2014-07-24 公開日 2014-09-17 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.09 Å) 主引用文献 Structure of a bacterial alpha 2-macroglobulin reveals mimicry of eukaryotic innate immunity. Nat Commun, 5, 2014
2QKI	Human C3c in complex with the inhibitor compstatin 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BROMIDE ION, Complement C3, ... 著者 Janssen, B.J.C, Halff, E.F, Lambris, J.D, Gros, P. 登録日 2007-07-11 公開日 2007-08-14 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure of compstatin in complex with complement component C3c reveals a new mechanism of complement inhibition. J.Biol.Chem., 282, 2007
3KLS	Structure of complement C5 in complex with SSL7 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CADMIUM ION, ... 著者 Laursen, N.S, Gordon, N, Hermans, S, Lorenz, N, Jackson, N, Wines, B, Spillner, E, Christensen, J.B, Jensen, M, Fredslund, F, Bjerre, M, Sottrup-Jensen, L, Fraser, J.D, Andersen, G.R. 登録日 2009-11-09 公開日 2009-11-24 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 Structural basis for inhibition of complement C5 by the SSL7 protein from Staphylococcus aureus Proc.Natl.Acad.Sci.USA, 107, 2010
3KM9	Structure of complement C5 in complex with the C-terminal beta-grasp domain of SSL7 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CADMIUM ION, ... 著者 Laursen, N.S, Gordon, N, Hermans, S, Lorenz, N, Jackson, N, Wines, B, Spillner, E, Christensen, J.B, Jensen, M, Fredslund, F, Bjerre, M, Sottrup-Jensen, L, Fraser, J.D, Andersen, G.R. 登録日 2009-11-10 公開日 2009-12-01 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (4.2 Å) 主引用文献 Structural basis for inhibition of complement C5 by the SSL7 protein from Staphylococcus aureus Proc.Natl.Acad.Sci.USA, 107, 2010
3L3O	Staphylococcal Complement Inhibitor (SCIN) in complex with Human Complement Component C3c 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C3, Staphylococcal complement inhibitor 著者 Geisbrecht, B.V, Garcia, B.G. 登録日 2009-12-17 公開日 2010-08-04 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3.405 Å) 主引用文献 Molecular Basis for Complement Recognition and Inhibition Determined by Crystallographic Studies of the Staphylococcal Complement Inhibitor (SCIN) Bound to C3c and C3b. J.Mol.Biol., 402, 2010
3L5N	Staphylococcal Complement Inhibitor (SCIN) in complex with Human Complement Component C3b 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C3, Staphylococcal complement inhibitor, ... 著者 Geisbrecht, B.V, Garcia, B.L. 登録日 2009-12-22 公開日 2010-08-04 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (7.536 Å) 主引用文献 Molecular Basis for Complement Recognition and Inhibition Determined by Crystallographic Studies of the Staphylococcal Complement Inhibitor (SCIN) Bound to C3c and C3b. J.Mol.Biol., 402, 2010
3NMS	Staphylococcal Complement Inhibitor (SCIN) in complex with Human Complement C3c 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C3, Staphylococcal complement inhibitor 著者 Geisbrecht, B.V, Garcia, B.L. 登録日 2010-06-22 公開日 2010-08-04 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (4.1 Å) 主引用文献 Molecular Basis for Complement Recognition and Inhibition Determined by Crystallographic Studies of the Staphylococcal Complement Inhibitor (SCIN) Bound to C3c and C3b. J.Mol.Biol., 402, 2010
3OHX	Molecular Basis for Complement Recognition and Inhibition Determined by Crystallographic Studies of the Staphylococcal Complement Inhibitor (SCIN) Bound to C3c and C3b 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C3, Staphylococcal complement inhibitor 著者 Geisbrecht, B.V, Garcia, B.L. 登録日 2010-08-18 公開日 2010-09-01 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (3.503 Å) 主引用文献 Molecular Basis for Complement Recognition and Inhibition Determined by Crystallographic Studies of the Staphylococcal Complement Inhibitor (SCIN) Bound to C3c and C3b. J.Mol.Biol., 402, 2010
5FO7	Crystal Structure of Human Complement C3b at 2.8 Angstrom resolution 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, COMPLEMENT C3 BETA CHAIN, COMPLEMENT C3B ALPHA' CHAIN 著者 Forneris, F, Wu, J, Xue, X, Gros, P. 登録日 2015-11-18 公開日 2016-04-06 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Regulators of Complement Activity Mediate Inhibitory Mechanisms Through a Common C3B-Binding Mode. Embo J., 35, 2016
7ZGJ	Trypanosoma brucei gambiense ISG65 in complex with human complement component C3 分子名称: 65 kDa invariant surface glycoprotein, putative, Complement C3, ... 著者 Suelzen, H, Zoll, S. 登録日 2022-04-03 公開日 2023-04-05 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.58 Å) 主引用文献 Cryo-EM structures of Trypanosoma brucei gambiense ISG65 with human complement C3 and C3b and their roles in alternative pathway restriction. Nat Commun, 14, 2023
7ZGK	Trypanosoma brucei gambiense ISG65 in complex with human complement component C3b 分子名称: 65 kDa invariant surface glycoprotein, putative, Complement C3 beta chain, ... 著者 Suelzen, H, Zoll, S. 登録日 2022-04-03 公開日 2023-04-05 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.59 Å) 主引用文献 Cryo-EM structures of Trypanosoma brucei gambiense ISG65 with human complement C3 and C3b and their roles in alternative pathway restriction. Nat Commun, 14, 2023

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