7ZGK

Trypanosoma brucei gambiense ISG65 in complex with human complement component C3b

Summary for 7ZGK

Entry DOI	10.2210/pdb7zgk/pdb
EMDB information	14708
Descriptor	Complement C3 beta chain, Complement C3b alpha' chain, 65 kDa invariant surface glycoprotein, putative (3 entities in total)
Functional Keywords	complex, complement, immune system
Biological source	Trypanosoma brucei gambiense More
Total number of polymer chains	3
Total formula weight	216290.98
Authors	Suelzen, H.,Zoll, S. (deposition date: 2022-04-03, release date: 2023-04-05, Last modification date: 2024-03-27)
Primary citation	Sulzen, H.,Began, J.,Dhillon, A.,Kereiche, S.,Pompach, P.,Votrubova, J.,Zahedifard, F.,Subrtova, A.,Safner, M.,Hubalek, M.,Thompson, M.,Zoltner, M.,Zoll, S. Cryo-EM structures of Trypanosoma brucei gambiense ISG65 with human complement C3 and C3b and their roles in alternative pathway restriction. Nat Commun, 14:2403-2403, 2023 Cited by PubMed: 37105991 DOI: 10.1038/s41467-023-37988-7 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.59 Å)

Structure validation