PDB: 181 件ウェブページステータス検索Chemie searchBIRD

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8QEV	Crystal structure of ornithine transcarbamylase from Arabidopsis thaliana (AtOTC) in complex with carbamoyl phosphate 分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Ornithine transcarbamylase, ... 著者 Nielipinski, M, Pietrzyk-Brzezinska, A, Sekula, B. 登録日 2023-09-01 公開日 2023-12-06 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Structural analysis and molecular substrate recognition properties of Arabidopsis thaliana ornithine transcarbamylase, the molecular target of phaseolotoxin produced by Pseudomonas syringae . Front Plant Sci, 14, 2023
8QEU	Crystal structure of ornithine transcarbamylase from Arabidopsis thaliana (AtOTC) in complex with ornithine 分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, L-ornithine, ... 著者 Nielipinski, M, Pietrzyk-Brzezinska, A, Sekula, B. 登録日 2023-09-01 公開日 2023-12-06 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structural analysis and molecular substrate recognition properties of Arabidopsis thaliana ornithine transcarbamylase, the molecular target of phaseolotoxin produced by Pseudomonas syringae . Front Plant Sci, 14, 2023
8BPL	Aspartate transcarbamoylase mutant (N2045C, R2238C) from Chaetomium thermophilum CAD-like bound to carbamoyl phosphate 分子名称: Carbamoyl-phosphate synthase (glutamine-hydrolyzing), GLYCEROL, PHOSPHORIC ACID MONO(FORMAMIDE)ESTER, ... 著者 del Cano-Ochoa, F, Ramon-Maiques, S. 登録日 2022-11-16 公開日 2023-02-01 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.58 Å) 主引用文献 A Tailored Strategy to Crosslink the Aspartate Transcarbamoylase Domain of the Multienzymatic Protein CAD. Molecules, 28, 2023
8BPS	Aspartate transcarbamoylase mutant (N2045C, R2238C) from Chaetomium thermophilum CAD-like in apo form 分子名称: Carbamoyl-phosphate synthase (glutamine-hydrolyzing), GLYCEROL 著者 del Cano-Ochoa, F, Ramon-Maiques, S. 登録日 2022-11-25 公開日 2023-02-01 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 A Tailored Strategy to Crosslink the Aspartate Transcarbamoylase Domain of the Multienzymatic Protein CAD. Molecules, 28, 2023
7ZID	Crystal Structure of truncated aspartate transcarbamoylase from Plasmodium falciparum in complex with BDA-14 分子名称: Aspartate carbamoyltransferase, GLYCEROL, SULFATE ION, ... 著者 Wang, C, Zhang, B. 登録日 2022-04-07 公開日 2022-08-31 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Discovery of Small-Molecule Allosteric Inhibitors of Pf ATC as Antimalarials. J.Am.Chem.Soc., 144, 2022
7ZCZ	Crystal Structure of truncated aspartate transcarbamoylase from Plasmodium falciparum with bound inhibitor 1-(4-chlorophenyl)methanamine 分子名称: 1-(4-CHLOROPHENYL)METHANAMINE, Aspartate carbamoyltransferase, SODIUM ION, ... 著者 Wang, C, Zhang, B. 登録日 2022-03-29 公開日 2022-08-31 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Discovery of Small-Molecule Allosteric Inhibitors of Pf ATC as Antimalarials. J.Am.Chem.Soc., 144, 2022
7ZHI	Crystal Structure of truncated aspartate transcarbamoylase from Plasmodium falciparum with bound inhibitor indole 分子名称: Aspartate carbamoyltransferase, INDOLE, SULFATE ION 著者 Wang, C, Zhang, B. 登録日 2022-04-06 公開日 2022-08-24 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.946 Å) 主引用文献 Discovery of Small-Molecule Allosteric Inhibitors of Pf ATC as Antimalarials. J.Am.Chem.Soc., 144, 2022
7ZGS	Crystal Structure of truncated aspartate transcarbamoylase from Plasmodium falciparum with bound inhibitor 2-phenylethan-1-amine 分子名称: 3-PHENYLPROPYLAMINE, Aspartate carbamoyltransferase, SODIUM ION, ... 著者 Wang, C, Zhang, B. 登録日 2022-04-04 公開日 2022-08-24 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.349 Å) 主引用文献 Discovery of Small-Molecule Allosteric Inhibitors of Pf ATC as Antimalarials. J.Am.Chem.Soc., 144, 2022
7ZP2	Crystal Structure of truncated aspartate transcarbamoylase from Plasmodium falciparum in complex with BDA-04 分子名称: Aspartate carbamoyltransferase, SODIUM ION, SULFATE ION, ... 著者 Wang, C, Zhang, B, Groves, M.R. 登録日 2022-04-26 公開日 2022-08-24 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.292 Å) 主引用文献 Discovery of Small-Molecule Allosteric Inhibitors of Pf ATC as Antimalarials. J.Am.Chem.Soc., 144, 2022
7ZEA	Crystal Structure of truncated aspartate transcarbamoylase from Plasmodium falciparum with bound inhibitor O-benzylhydroxylamine 分子名称: Aspartate carbamoyltransferase, O-benzylhydroxylamine, SODIUM ION, ... 著者 Wang, C, Zhang, B. 登録日 2022-03-30 公開日 2022-08-24 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.448 Å) 主引用文献 Discovery of Small-Molecule Allosteric Inhibitors of Pf ATC as Antimalarials. J.Am.Chem.Soc., 144, 2022
7ZST	Crystal Structure of truncated aspartate transcarbamoylase from Plasmodium falciparum in complex with FLA-01 分子名称: 2-azanyl-~{N}-(2-methoxyethyl)-5-phenyl-thiophene-3-carboxamide, Aspartate carbamoyltransferase, GLYCEROL, ... 著者 Wang, C, Zhang, B, Groves, M.R. 登録日 2022-05-08 公開日 2022-08-24 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Discovery of Small-Molecule Allosteric Inhibitors of Pf ATC as Antimalarials. J.Am.Chem.Soc., 144, 2022
7TMD	Crystal structure of Ornithine carbamoyltransferase from Klebsiella pneumoniae 分子名称: BROMIDE ION, IODIDE ION, Ornithine carbamoyltransferase 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2022-01-19 公開日 2022-02-02 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Crystal structure of Ornithine carbamoyltransferase from Klebsiella pneumoniae To be published
7NOS	Crystal structure of Mycobacterium tuberculosis ArgF in complex with 4-bromo-6-(trifluoromethyl)-1H-benzo[d]imidazole. 分子名称: 4-bromanyl-6-(trifluoromethyl)-1~{H}-benzimidazole, Ornithine carbamoyltransferase, PHOSPHATE ION 著者 Mendes, V, Gupta, P, Burgess, A, Sebastian-Perez, V, Cattermole, E, Meghir, C, Blundell, T.L. 登録日 2021-02-25 公開日 2021-06-30 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 A fragment-based approach to assess the ligandability of ArgB, ArgC, ArgD and ArgF in the L-arginine biosynthetic pathway of Mycobacterium tuberculosis Comput Struct Biotechnol J, 19, 2021
7NOU	Crystal structure of Mycobacterium tuberculosis ArgF in complex with (3,5-dichlorophenyl)boronic acid. 分子名称: Ornithine carbamoyltransferase, PHOSPHATE ION, [3,5-bis(chloranyl)phenyl]-oxidanyl-oxidanylidene-boron 著者 Mendes, V, Gupta, P, Burgess, A, Sebastian-Perez, V, Cattermole, E, Meghir, C, Blundell, T.L. 登録日 2021-02-25 公開日 2021-06-30 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 A fragment-based approach to assess the ligandability of ArgB, ArgC, ArgD and ArgF in the L-arginine biosynthetic pathway of Mycobacterium tuberculosis Comput Struct Biotechnol J, 19, 2021
7NNZ	Crystal structure of Mycobacterium tuberculosis ArgF in complex with 5-methyl-4-phenylthiazol-2-amine. 分子名称: 5-methyl-4-phenyl-1,3-thiazol-2-amine, Ornithine carbamoyltransferase, PHOSPHATE ION 著者 Mendes, V, Gupta, P, Burgess, A, Sebastian-Perez, V, Cattermole, E, Meghir, C, Blundell, T.L. 登録日 2021-02-25 公開日 2021-06-30 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.68 Å) 主引用文献 A fragment-based approach to assess the ligandability of ArgB, ArgC, ArgD and ArgF in the L-arginine biosynthetic pathway of Mycobacterium tuberculosis Comput Struct Biotechnol J, 19, 2021
7NNF	Crystal structure of Mycobacterium tuberculosis ArgF in apo form. 分子名称: Ornithine carbamoyltransferase, PHOSPHATE ION 著者 Mendes, V, Gupta, P, Burgess, A, Sebastian-Perez, V, Cattermole, E, Meghir, C, Blundell, T.L. 登録日 2021-02-24 公開日 2021-06-30 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.52 Å) 主引用文献 A fragment-based approach to assess the ligandability of ArgB, ArgC, ArgD and ArgF in the L-arginine biosynthetic pathway of Mycobacterium tuberculosis Comput Struct Biotechnol J, 19, 2021
7NNY	Crystal structure of Mycobacterium tuberculosis ArgF in complex with naphthalen-1-ol. 分子名称: 1-NAPHTHOL, Ornithine carbamoyltransferase, PHOSPHATE ION 著者 Mendes, V, Gupta, P, Burgess, A, Sebastian-Perez, V, Cattermole, E, Meghir, C, Blundell, T.L. 登録日 2021-02-25 公開日 2021-06-30 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.57 Å) 主引用文献 A fragment-based approach to assess the ligandability of ArgB, ArgC, ArgD and ArgF in the L-arginine biosynthetic pathway of Mycobacterium tuberculosis Comput Struct Biotechnol J, 19, 2021
7NNV	Crystal structure of Mycobacterium tuberculosis ArgF in complex with carbamoyl phosphate. 分子名称: 1,2-ETHANEDIOL, Ornithine carbamoyltransferase, PHOSPHATE ION, ... 著者 Mendes, V, Gupta, P, Burgess, A, Sebastian-Perez, V, Cattermole, E, Meghir, C, Blundell, T.L. 登録日 2021-02-25 公開日 2021-06-30 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.67 Å) 主引用文献 A fragment-based approach to assess the ligandability of ArgB, ArgC, ArgD and ArgF in the L-arginine biosynthetic pathway of Mycobacterium tuberculosis Comput Struct Biotechnol J, 19, 2021
7NOV	Crystal structure of Mycobacterium tuberculosis ArgF in complex with (4-methyl-3-nitrophenyl)boronic acid. 分子名称: (4-methyl-3-nitro-phenyl)-oxidanyl-oxidanylidene-boron, Ornithine carbamoyltransferase, PHOSPHATE ION 著者 Mendes, V, Gupta, P, Burgess, A, Sebastian-Perez, V, Cattermole, E, Meghir, C, Blundell, T.L. 登録日 2021-02-26 公開日 2021-06-30 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 A fragment-based approach to assess the ligandability of ArgB, ArgC, ArgD and ArgF in the L-arginine biosynthetic pathway of Mycobacterium tuberculosis Comput Struct Biotechnol J, 19, 2021
7NNW	Crystal structure of Mycobacterium tuberculosis ArgF in complex with methyl 4-hydroxy-3-iodobenzoate. 分子名称: Ornithine carbamoyltransferase, PHOSPHATE ION, methyl 3-iodanyl-4-oxidanyl-benzoate 著者 Mendes, V, Gupta, P, Burgess, A, Sebastian-Perez, V, Cattermole, E, Meghir, C, Blundell, T.L. 登録日 2021-02-25 公開日 2021-06-30 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 A fragment-based approach to assess the ligandability of ArgB, ArgC, ArgD and ArgF in the L-arginine biosynthetic pathway of Mycobacterium tuberculosis Comput Struct Biotechnol J, 19, 2021
7NP0	Crystal structure of Mycobacterium tuberculosis ArgF in complex with (4-nitrophenyl)boronic acid. 分子名称: Ornithine carbamoyltransferase, PHOSPHATE ION, p-nitrophenylboronic acid 著者 Mendes, V, Gupta, P, Burgess, A, Sebastian-Perez, V, Cattermole, E, Meghir, C, Blundell, T.L. 登録日 2021-02-26 公開日 2021-06-30 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 A fragment-based approach to assess the ligandability of ArgB, ArgC, ArgD and ArgF in the L-arginine biosynthetic pathway of Mycobacterium tuberculosis Comput Struct Biotechnol J, 19, 2021
7NOR	Crystal structure of Mycobacterium tuberculosis ArgF in complex with 2-fluoro-4-hydroxybenzonitrile. 分子名称: 2-fluoro-4-hydroxybenzonitrile, Ornithine carbamoyltransferase, PHOSPHATE ION 著者 Mendes, V, Gupta, P, Burgess, A, Sebastian-Perez, V, Cattermole, E, Meghir, C, Blundell, T.L. 登録日 2021-02-25 公開日 2021-06-30 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.59 Å) 主引用文献 A fragment-based approach to assess the ligandability of ArgB, ArgC, ArgD and ArgF in the L-arginine biosynthetic pathway of Mycobacterium tuberculosis Comput Struct Biotechnol J, 19, 2021
6YPO	Arabidopsis aspartate transcarbamoylase bound to UMP 分子名称: GLYCEROL, PYRB, URIDINE-5'-MONOPHOSPHATE 著者 Ramon Maiques, S, Del Cano Ochoa, F, Bellin, L, Mohlmann, T. 登録日 2020-04-16 公開日 2021-03-03 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.67 Å) 主引用文献 Mechanisms of feedback inhibition and sequential firing of active sites in plant aspartate transcarbamoylase. Nat Commun, 12, 2021
6YS6	Arabidopsis aspartate transcarbamoylase complex with PALA 分子名称: GLYCEROL, N-(PHOSPHONACETYL)-L-ASPARTIC ACID, PYRB, ... 著者 Ramon Maiques, S, Del Cano Ochoa, F, Bellin, L, Mohlmann, T. 登録日 2020-04-21 公開日 2021-03-03 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Mechanisms of feedback inhibition and sequential firing of active sites in plant aspartate transcarbamoylase. Nat Commun, 12, 2021
6YSP	Arabidopsis aspartate transcarbamoylase complex with PALA and carbamoyl phosphate 分子名称: GLYCEROL, N-(PHOSPHONACETYL)-L-ASPARTIC ACID, PHOSPHORIC ACID MONO(FORMAMIDE)ESTER, ... 著者 Ramon Maiques, S, Del Cano Ochoa, F, Bellin, L, Mohlmann, T. 登録日 2020-04-23 公開日 2021-03-03 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.38 Å) 主引用文献 Mechanisms of feedback inhibition and sequential firing of active sites in plant aspartate transcarbamoylase. Nat Commun, 12, 2021

 

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