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7NNV

Crystal structure of Mycobacterium tuberculosis ArgF in complex with carbamoyl phosphate.

Summary for 7NNV
Entry DOI10.2210/pdb7nnv/pdb
DescriptorOrnithine carbamoyltransferase, PHOSPHATE ION, PHOSPHORIC ACID MONO(FORMAMIDE)ESTER, ... (5 entities in total)
Functional Keywordsargf, ornithine carbamoyltransferase, transferase
Biological sourceMycobacterium tuberculosis H37Rv
Total number of polymer chains6
Total formula weight201323.21
Authors
Mendes, V.,Gupta, P.,Burgess, A.,Sebastian-Perez, V.,Cattermole, E.,Meghir, C.,Blundell, T.L. (deposition date: 2021-02-25, release date: 2021-06-30, Last modification date: 2024-01-31)
Primary citationGupta, P.,Thomas, S.E.,Zaidan, S.A.,Pasillas, M.A.,Cory-Wright, J.,Sebastian-Perez, V.,Burgess, A.,Cattermole, E.,Meghir, C.,Abell, C.,Coyne, A.G.,Jacobs, W.R.,Blundell, T.L.,Tiwari, S.,Mendes, V.
A fragment-based approach to assess the ligandability of ArgB, ArgC, ArgD and ArgF in the L-arginine biosynthetic pathway of Mycobacterium tuberculosis
Comput Struct Biotechnol J, 19:3491-3506, 2021
Cited by
DOI: 10.1016/j.csbj.2021.06.006
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.67 Å)
Structure validation

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