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7NNW

Crystal structure of Mycobacterium tuberculosis ArgF in complex with methyl 4-hydroxy-3-iodobenzoate.

Summary for 7NNW
Entry DOI10.2210/pdb7nnw/pdb
DescriptorOrnithine carbamoyltransferase, PHOSPHATE ION, methyl 3-iodanyl-4-oxidanyl-benzoate, ... (4 entities in total)
Functional Keywordsargf, ornithine carbamoyltransferase, transferase
Biological sourceMycobacterium tuberculosis H37Rv
Total number of polymer chains6
Total formula weight201488.03
Authors
Mendes, V.,Gupta, P.,Burgess, A.,Sebastian-Perez, V.,Cattermole, E.,Meghir, C.,Blundell, T.L. (deposition date: 2021-02-25, release date: 2021-06-30, Last modification date: 2024-01-31)
Primary citationGupta, P.,Thomas, S.E.,Zaidan, S.A.,Pasillas, M.A.,Cory-Wright, J.,Sebastian-Perez, V.,Burgess, A.,Cattermole, E.,Meghir, C.,Abell, C.,Coyne, A.G.,Jacobs, W.R.,Blundell, T.L.,Tiwari, S.,Mendes, V.
A fragment-based approach to assess the ligandability of ArgB, ArgC, ArgD and ArgF in the L-arginine biosynthetic pathway of Mycobacterium tuberculosis
Comput Struct Biotechnol J, 19:3491-3506, 2021
Cited by
DOI: 10.1016/j.csbj.2021.06.006
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.78 Å)
Structure validation

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