PDB: 117 resultsInfo pagesStatus searchChemie searchBIRD

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6KDP	Crystal structure of human DNMT3B-DNMT3L complex (II) Descriptor: DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3B, FORMIC ACID, ... Authors: Lin, C.-C, Chen, Y.-P, Yang, W.-Z, Shen, C.-K, Yuan, H.S. Deposit date: 2019-07-02 Release date: 2020-02-19 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.93 Å) Cite: Structural insights into CpG-specific DNA methylation by human DNA methyltransferase 3B. Nucleic Acids Res., 48, 2020
6KDB	Crystal structure of human DNMT3B-DNMT3L in complex with DNA containing CpGpT site Descriptor: DNA (25-MER), DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3B, ... Authors: Lin, C.-C, Chen, Y.-P, Yang, W.-Z, Shen, C.-K, Yuan, H.S. Deposit date: 2019-07-01 Release date: 2020-02-19 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.862 Å) Cite: Structural insights into CpG-specific DNA methylation by human DNA methyltransferase 3B. Nucleic Acids Res., 48, 2020
6KDT	Crystal structure of human DNMT3B (Q772R)-DNMT3L complex Descriptor: DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3B, FORMIC ACID, ... Authors: Lin, C.-C, Chen, Y.-P, Yang, W.-Z, Shen, C.-K, Yuan, H.S. Deposit date: 2019-07-02 Release date: 2020-02-19 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.87 Å) Cite: Structural insights into CpG-specific DNA methylation by human DNA methyltransferase 3B. Nucleic Acids Res., 48, 2020
6KDA	Crystal structure of human DNMT3B-DNMT3L in complex with DNA containing CpGpG site Descriptor: DNA (25-MER), DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3B, ... Authors: Lin, C.-C, Chen, Y.-P, Yang, W.-Z, Shen, C.-K, Yuan, H.S. Deposit date: 2019-07-01 Release date: 2020-02-19 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.909 Å) Cite: Structural insights into CpG-specific DNA methylation by human DNA methyltransferase 3B. Nucleic Acids Res., 48, 2020
6FDF	Crystal structure of S. pombe Dnmt2 methyltransferase Descriptor: GLYCEROL, S-ADENOSYL-L-HOMOCYSTEINE, tRNA (cytosine(38)-C(5))-methyltransferase Authors: Johannsson, S, Neumann, P, Ficner, R. Deposit date: 2017-12-22 Release date: 2018-06-20 Method: X-RAY DIFFRACTION (1.697 Å) Cite: Structural insights into the stimulation of S. pombe Dnmt2 catalytic efficiency by the tRNA nucleoside queuosine. Sci Rep, 8, 2018
5YX2	Crystal structure of DNMT3A-DNMT3L in complex with DNA containing two CpG sites Descriptor: DNA (25-MER), DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3A, ... Authors: Zhang, Z.M, Song, J. Deposit date: 2017-12-01 Release date: 2018-01-31 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.653 Å) Cite: Structural basis for DNMT3A-mediated de novo DNA methylation. Nature, 554, 2018
6F57	Crystal structure of DNMT3A-DNMT3L in complex with single CpG-containing DNA Descriptor: DNA (5'-D(*AP*GP*AP*GP*CP*GP*CP*AP*TP*G)-3'), DNA (5'-D(*CP*AP*TP*GP*ZP*GP*CP*TP*CP*T)-3'), DNA (cytosine-5)-methyltransferase 3-like, ... Authors: Zhang, Z.M, Song, J. Deposit date: 2017-12-01 Release date: 2018-01-31 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (3.098 Å) Cite: Structural basis for DNMT3A-mediated de novo DNA methylation. Nature, 554, 2018
6BRR	Crystal structure of DNMT3A (R836A)-DNMT3L in complex with DNA containing two CpG sites Descriptor: DNA (25-MER), DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3A, ... Authors: Zhang, Z.M, Song, J. Deposit date: 2017-11-30 Release date: 2018-01-31 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.97 Å) Cite: Structural basis for DNMT3A-mediated de novo DNA methylation. Nature, 554, 2018
5GUT	The crystal structure of mouse DNMT1 (731-1602) mutant - N1248A Descriptor: DNA (cytosine-5)-methyltransferase 1, S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION, ... Authors: Chen, S.J, Ye, F. Deposit date: 2016-08-31 Release date: 2017-09-06 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.099 Å) Cite: Biochemical Studies and Molecular Dynamic Simulations Reveal the Molecular Basis of Conformational Changes in DNA Methyltransferase-1. ACS Chem. Biol., 13, 2018
5GUV	The crystal structure of mouse DNMT1 (731-1602) mutant - R1279D Descriptor: DNA (cytosine-5)-methyltransferase 1, ZINC ION Authors: Ye, F, Chen, S.J. Deposit date: 2016-08-31 Release date: 2017-08-30 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (3.078 Å) Cite: Biochemical Studies and Molecular Dynamic Simulations Reveal the Molecular Basis of Conformational Changes in DNA Methyltransferase-1. ACS Chem. Biol., 13, 2018
5LOD	Crystal structure of HhaI DNA methyltransferase in APO form Descriptor: Modification methylase HhaI, SULFATE ION Authors: Rondelet, G, Wouters, J. Deposit date: 2016-08-09 Release date: 2017-08-16 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Inhibition studies of DNA methyltransferases by maleimide derivatives of RG108 as non-nucleoside inhibitors. Future Med Chem, 9, 2017
5WY1	Crystal structure of mouse DNA methyltransferase 1 (T1505A mutant) Descriptor: DNA (cytosine-5)-methyltransferase 1, ZINC ION Authors: Kanada, K, Takeshita, K, Suetake, I, Tajima, S, Nakagawa, A. Deposit date: 2017-01-10 Release date: 2017-05-24 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (3.27 Å) Cite: Conserved threonine 1505 in the catalytic domain stabilizes mouse DNA methyltransferase 1 J. Biochem., 162, 2017
5CIY	Structural basis of the recognition of H3K36me3 by DNMT3B PWWP domain Descriptor: DNA (5'-D(P*CP*CP*AP*TP*GP*CP*GP*CP*TP*GP*AP*C)-3'), DNA (5'-D(P*GP*TP*CP*AP*GP*(3DR)P*GP*CP*AP*TP*GP*G)-3'), Modification methylase HhaI, ... Authors: Rondelet, G, DAL MASO, T, Willems, L, Wouters, J. Deposit date: 2015-07-13 Release date: 2016-03-30 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.594 Å) Cite: Structural basis for recognition of histone H3K36me3 nucleosome by human de novo DNA methyltransferases 3A and 3B. J.Struct.Biol., 194, 2016
4WXX	The crystal structure of human DNMT1(351-1600) Descriptor: DNA (cytosine-5)-methyltransferase 1, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION Authors: Zhang, Z.M, Song, J. Deposit date: 2014-11-14 Release date: 2015-07-15 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.622 Å) Cite: Crystal Structure of Human DNA Methyltransferase 1. J.Mol.Biol., 427, 2015
4YOC	Crystal Structure of human DNMT1 and USP7/HAUSP complex Descriptor: DNA (cytosine-5)-methyltransferase 1, Ubiquitin carboxyl-terminal hydrolase 7, ZINC ION Authors: Cheng, J, Yang, H, Fang, J, Gong, R, Wang, P, Li, Z, Xu, Y. Deposit date: 2015-03-11 Release date: 2015-05-27 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.916 Å) Cite: Molecular mechanism for USP7-mediated DNMT1 stabilization by acetylation. Nat Commun, 6, 2015
4U7P	Crystal structure of DNMT3A-DNMT3L complex Descriptor: DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3A, S-ADENOSYL-L-HOMOCYSTEINE, ... Authors: Wang, L, Guo, X, Li, J, Xiao, J, Yin, X, He, S, Wang, J, Xu, Y. Deposit date: 2014-07-31 Release date: 2014-11-12 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (3.821 Å) Cite: Structural insight into autoinhibition and histone H3-induced activation of DNMT3A Nature, 517, 2015
4U7T	Crystal structure of DNMT3A-DNMT3L in complex with histone H3 Descriptor: DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3A, S-ADENOSYL-L-HOMOCYSTEINE, ... Authors: Guo, X, Wang, L, Yin, X, Li, J, Xiao, J, He, S, Wang, J, Xu, Y. Deposit date: 2014-07-31 Release date: 2014-11-12 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Structural insight into autoinhibition and histone H3-induced activation of DNMT3A Nature, 517, 2015
4ONJ	Crystal structure of the catalytic domain of ntDRM Descriptor: DNA methyltransferase, SINEFUNGIN Authors: Du, J, Patel, D.J. Deposit date: 2014-01-28 Release date: 2014-06-04 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.807 Å) Cite: Molecular Mechanism of Action of Plant DRM De Novo DNA Methyltransferases. Cell(Cambridge,Mass.), 157, 2014
4ONQ	Crystal structure of ntDRM E283S/R309S/F310S/Y590S/D591S mutant Descriptor: DNA methyltransferase, SINEFUNGIN Authors: Du, J, Patel, D.J. Deposit date: 2014-01-28 Release date: 2014-06-04 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.502 Å) Cite: Molecular Mechanism of Action of Plant DRM De Novo DNA Methyltransferases. Cell(Cambridge,Mass.), 157, 2014
4DKJ	CpG specific methyltransferase in complex with target DNA Descriptor: Cytosine-specific methyltransferase, DNA (5'-D(*CP*CP*AP*CP*AP*TP*GP*(C37)P*GP*CP*TP*GP*AP*A)-3'), DNA (5'-D(*GP*TP*TP*CP*AP*GP*(5CM)P*GP*CP*AP*TP*GP*TP*G)-3'), ... Authors: Wojciechowski, M, Czapinska, H, Bochtler, M. Deposit date: 2012-02-03 Release date: 2012-12-05 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.15 Å) Cite: CpG underrepresentation and the bacterial CpG-specific DNA methyltransferase M.MpeI. Proc.Natl.Acad.Sci.USA, 110, 2013
4H0N	Crystal structure of Spodoptera frugiperda DNMT2 E260A/E261A/K263A mutant Descriptor: CALCIUM ION, DNMT2, S-ADENOSYL-L-HOMOCYSTEINE Authors: Li, S, Du, J, Yang, H, Yin, J, Zhong, J, Ding, J. Deposit date: 2012-09-09 Release date: 2012-11-14 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.712 Å) Cite: Functional and structural characterization of DNMT2 from Spodoptera frugiperda. J Mol Cell Biol, 5, 2013
4FSX	crystal structure of Se-substituted Zea mays ZMET2 in complex with SAH Descriptor: DNA (cytosine-5)-methyltransferase 1, S-ADENOSYL-L-HOMOCYSTEINE Authors: Du, J, Patel, D.J. Deposit date: 2012-06-27 Release date: 2012-10-17 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Dual Binding of Chromomethylase Domains to H3K9me2-Containing Nucleosomes Directs DNA Methylation in Plants. Cell(Cambridge,Mass.), 151, 2012
4FT4	crystal structure of Zea mays ZMET2 in complex H3(1-32)K9me2 peptide and SAH Descriptor: DNA (cytosine-5)-methyltransferase 1, H3(1-32)K9me2 peptide, S-ADENOSYL-L-HOMOCYSTEINE Authors: Du, J, Patel, D.J. Deposit date: 2012-06-27 Release date: 2012-10-17 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Dual Binding of Chromomethylase Domains to H3K9me2-Containing Nucleosomes Directs DNA Methylation in Plants. Cell(Cambridge,Mass.), 151, 2012
4FT2	crystal structure of Zea mays ZMET2 in complex H3(1-15)K9me2 peptide and SAH Descriptor: DNA (cytosine-5)-methyltransferase 1, H3 peptide, S-ADENOSYL-L-HOMOCYSTEINE Authors: Du, J, Patel, D.J. Deposit date: 2012-06-27 Release date: 2012-10-17 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Dual Binding of Chromomethylase Domains to H3K9me2-Containing Nucleosomes Directs DNA Methylation in Plants. Cell(Cambridge,Mass.), 151, 2012
3UBT	Crystal Structure of C71S Mutant of DNA Cytosine-5 Methyltransferase M.HaeIII Bound to DNA Descriptor: 5'-D(*TP*GP*GP*CP*CP*A)-3', ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, ... Authors: Verdine, G.L, Didovyk, A. Deposit date: 2011-10-24 Release date: 2012-10-03 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.502 Å) Cite: Structural origins of DNA target selection and nucleobase extrusion by a DNA Cytosine methyltransferase. J.Biol.Chem., 287, 2012

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