PDB: 143 件ウェブページステータス検索Chemie searchBIRD

---

4ZDJ	Crystal structure of the M. tuberculosis CTP synthase PyrG in complex with two UTP molecules 分子名称: CTP synthase, GLYCEROL, MAGNESIUM ION, ... 著者 Bellinzoni, M, Barilone, N, Alzari, P.M. 登録日 2015-04-17 公開日 2015-07-01 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Thiophenecarboxamide Derivatives Activated by EthA Kill Mycobacterium tuberculosis by Inhibiting the CTP Synthetase PyrG. Chem.Biol., 22, 2015
4ZDI	Crystal structure of the M. tuberculosis CTP synthase PyrG (apo form) 分子名称: CALCIUM ION, CTP synthase 著者 Bellinzoni, M, Barilone, N, Alzari, P.M. 登録日 2015-04-17 公開日 2015-07-01 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.52 Å) 主引用文献 Thiophenecarboxamide Derivatives Activated by EthA Kill Mycobacterium tuberculosis by Inhibiting the CTP Synthetase PyrG. Chem.Biol., 22, 2015
1GPW	Structural evidence for ammonia tunneling across the (beta/alpha)8 barrel of the imidazole glycerol phosphate synthase bienzyme complex. 分子名称: AMIDOTRANSFERASE HISH, HISF PROTEIN, PHOSPHATE ION 著者 Walker, M, Beismann-Driemeyer, S, Sterner, R, Wilmanns, M. 登録日 2001-11-12 公開日 2002-02-10 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural Evidence for Ammonia Tunneling Across the (Beta Alpha)(8) Barrel of the Imidazole Glycerol Phosphate Synthase Bienzyme Complex. Structure, 10, 2002
1GPM	ESCHERICHIA COLI GMP SYNTHETASE COMPLEXED WITH AMP AND PYROPHOSPHATE 分子名称: ADENOSINE MONOPHOSPHATE, CITRIC ACID, GMP SYNTHETASE, ... 著者 Tesmer, J.J.G. 登録日 1995-04-04 公開日 1996-01-29 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The crystal structure of GMP synthetase reveals a novel catalytic triad and is a structural paradigm for two enzyme families. Nat.Struct.Biol., 3, 1996
1I1Q	STRUCTURE OF THE COOPERATIVE ALLOSTERIC ANTHRANILATE SYNTHASE FROM SALMONELLA TYPHIMURIUM 分子名称: ANTHRANILATE SYNTHASE COMPONENT I, ANTHRANILATE SYNTHASE COMPONENT II, TRYPTOPHAN 著者 Morollo, A.A, Eck, M.J. 登録日 2001-02-02 公開日 2001-04-18 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure of the cooperative allosteric anthranilate synthase from Salmonella typhimurium. Nat.Struct.Biol., 8, 2001
1I7Q	ANTHRANILATE SYNTHASE FROM S. MARCESCENS 分子名称: ANTHRANILATE SYNTHASE, BENZOIC ACID, GLUTAMIC ACID, ... 著者 Spraggon, G, Kim, C, Nguyen-Huu, X, Yee, M.-C, Yanofsky, C, Mills, S.E. 登録日 2001-03-10 公開日 2001-05-16 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 The structures of anthranilate synthase of Serratia marcescens crystallized in the presence of (i) its substrates, chorismate and glutamine, and a product, glutamate, and (ii) its end-product inhibitor, L-tryptophan. Proc.Natl.Acad.Sci.USA, 98, 2001
1I7S	ANTHRANILATE SYNTHASE FROM SERRATIA MARCESCENS IN COMPLEX WITH ITS END PRODUCT INHIBITOR L-TRYPTOPHAN 分子名称: ANTHRANILATE SYNTHASE, TRPG, TRYPTOPHAN 著者 Spraggon, G, Kim, C, Nguyen-Huu, X, Yee, M.-C, Yanofsky, C, Mills, S.E. 登録日 2001-03-10 公開日 2001-05-16 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 The structures of anthranilate synthase of Serratia marcescens crystallized in the presence of (i) its substrates, chorismate and glutamine, and a product, glutamate, and (ii) its end-product inhibitor, L-tryptophan. Proc.Natl.Acad.Sci.USA, 98, 2001
4L95	Crystal structure of gamma glutamyl hydrolase (H218N) from zebrafish 分子名称: GLYCEROL, Gamma-glutamyl hydrolase 著者 Chuankhayan, P, Kao, T.-T, Chen, C.-J, Fu, T.-F. 登録日 2013-06-18 公開日 2014-05-14 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.34 Å) 主引用文献 Structural insights into the hydrolysis and polymorphism of methotrexate polyglutamate by zebrafish gamma-glutamyl hydrolase J.Med.Chem., 56, 2013
4L8W	Crystal structure of gamma glutamyl hydrolase (H218N) from zebrafish complex with MTX polyglutamate 分子名称: D-GLUTAMIC ACID, Gamma-glutamyl hydrolase, METHOTREXATE 著者 Chuankhayan, P, Kao, T.-T, Chen, C.-J, Fu, T.-F. 登録日 2013-06-18 公開日 2014-05-14 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.39 Å) 主引用文献 Structural insights into the hydrolysis and polymorphism of methotrexate polyglutamate by zebrafish gamma-glutamyl hydrolase J.Med.Chem., 56, 2013
4L8Y	Crystal structure of gamma-glutamyl hydrolase (C108A) from zebrafish 分子名称: Gamma-glutamyl hydrolase 著者 Chuankhayan, P, Kao, T.-T, Chen, C.-J, Fu, T.-F. 登録日 2013-06-18 公開日 2014-05-14 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Structural insights into the hydrolysis and polymorphism of methotrexate polyglutamate by zebrafish gamma-glutamyl hydrolase J.Med.Chem., 56, 2013
4L8F	Crystal structure of gamma-glutamyl hydrolase (C108A) complex with MTX 分子名称: Gamma-glutamyl hydrolase, METHOTREXATE 著者 Chuankhayan, P, Kao, T.-T, Chen, C.-J, Fu, T.-F. 登録日 2013-06-17 公開日 2014-05-14 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Structural insights into the hydrolysis and polymorphism of methotrexate polyglutamate by zebrafish gamma-glutamyl hydrolase J.Med.Chem., 56, 2013
4L7Q	Crystal structure of gamma glutamyl hydrolase (wild-type) from zebrafish 分子名称: GLYCEROL, Gamma-glutamyl hydrolase 著者 Chuankhayan, P, Kao, T.-T, Chen, C.-J, Fu, T.-F. 登録日 2013-06-14 公開日 2014-05-14 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural insights into the hydrolysis and polymorphism of methotrexate polyglutamate by zebrafish gamma-glutamyl hydrolase J.Med.Chem., 56, 2013
5DOU	Crystal Structure of Human Carbamoyl phosphate synthetase I (CPS1), ligand-bound form 分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ... 著者 de Cima, S, Polo, L.M, Fita, I, Rubio, V. 登録日 2015-09-11 公開日 2015-12-09 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structure of human carbamoyl phosphate synthetase: deciphering the on/off switch of human ureagenesis. Sci Rep, 5, 2015
5DOT	Crystal Structure of Human Carbamoyl phosphate synthetase I (CPS1), apo form 分子名称: 1,2-ETHANEDIOL, Carbamoyl-phosphate synthase [ammonia], mitochondrial, ... 著者 Polo, L.M, de Cima, S, Fita, I, Rubio, V. 登録日 2015-09-11 公開日 2015-12-09 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure of human carbamoyl phosphate synthetase: deciphering the on/off switch of human ureagenesis. Sci Rep, 5, 2015
1VCO	Crystal Structure of T.th. HB8 CTP synthetase complex with Glutamine 分子名称: CTP synthetase, GLUTAMINE 著者 Goto, M, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2004-03-10 公開日 2004-08-31 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Crystal Structures of CTP Synthetase Reveal ATP, UTP, and Glutamine Binding Sites Structure, 12, 2004
1VCM	Crystal Structure of T.th. HB8 CTP synthetase 分子名称: CTP synthetase 著者 Goto, M, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2004-03-10 公開日 2004-08-31 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Crystal Structures of CTP Synthetase Reveal ATP, UTP, and Glutamine Binding Sites Structure, 12, 2004
1VCN	Crystal Structure of T.th. HB8 CTP synthetase complex with Sulfate anion 分子名称: CTP synthetase, SULFATE ION 著者 Goto, M, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2004-03-10 公開日 2004-08-31 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Crystal Structures of CTP Synthetase Reveal ATP, UTP, and Glutamine Binding Sites Structure, 12, 2004
1A9X	CARBAMOYL PHOSPHATE SYNTHETASE: CAUGHT IN THE ACT OF GLUTAMINE HYDROLYSIS 分子名称: ADENOSINE-5'-DIPHOSPHATE, CARBAMOYL PHOSPHATE SYNTHETASE (LARGE CHAIN), CARBAMOYL PHOSPHATE SYNTHETASE (SMALL CHAIN), ... 著者 Thoden, J, Holden, H. 登録日 1998-04-14 公開日 1998-10-21 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Carbamoyl phosphate synthetase: caught in the act of glutamine hydrolysis. Biochemistry, 37, 1998
5TKV	X-RAY CRYSTAL STRUCTURE OF THE "CLOSED" CONFORMATION OF CTP-INHIBITED E. COLI CYTIDINE TRIPHOSPHATE (CTP) SYNTHETASE 分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, CTP synthase, ... 著者 Baldwin, E.P, Endrizzi, J.A. 登録日 2016-10-07 公開日 2017-04-26 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Human CTP synthase filament structure reveals the active enzyme conformation. Nat. Struct. Mol. Biol., 24, 2017
1C30	CRYSTAL STRUCTURE OF CARBAMOYL PHOSPHATE SYNTHETASE: SMALL SUBUNIT MUTATION C269S 分子名称: ADENOSINE-5'-DIPHOSPHATE, CARBAMOYL PHOSPHATE SYNTHETASE: LARGE SUBUNIT, CARBAMOYL PHOSPHATE SYNTHETASE: SMALL SUBUNIT, ... 著者 Thoden, J.B, Huang, X, Raushel, F.M, Holden, H.M. 登録日 1999-07-24 公開日 1999-12-10 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The small subunit of carbamoyl phosphate synthetase: snapshots along the reaction pathway. Biochemistry, 38, 1999
1C3O	CRYSTAL STRUCTURE OF THE CARBAMOYL PHOSPHATE SYNTHETASE: SMALL SUBUNIT MUTANT C269S WITH BOUND GLUTAMINE 分子名称: ADENOSINE-5'-DIPHOSPHATE, CARBAMOYL PHOSPHATE SYNTHETASE: LARGE SUBUNIT, CARBAMOYL PHOSPHATE SYNTHETASE: SMALL SUBUNIT, ... 著者 Thoden, J.B, Huang, X, Raushel, F.M, Holden, H.M. 登録日 1999-07-28 公開日 1999-12-10 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The small subunit of carbamoyl phosphate synthetase: snapshots along the reaction pathway. Biochemistry, 38, 1999
5U05	Cryo-EM structure of the E. coli CTP synthase tetramer 分子名称: CTP synthase 著者 Lynch, E.M, Hicks, D.R, Kollman, J.M. 登録日 2016-11-22 公開日 2017-04-26 最終更新日 2018-07-18 実験手法 ELECTRON MICROSCOPY (7.9 Å) 主引用文献 Human CTP synthase filament structure reveals the active enzyme conformation. Nat. Struct. Mol. Biol., 24, 2017
5U03	Cryo-EM structure of the human CTP synthase filament 分子名称: ADENOSINE-5'-TRIPHOSPHATE, CTP synthase 1, URIDINE 5'-TRIPHOSPHATE 著者 Lynch, E.M, Kollman, J.M. 登録日 2016-11-22 公開日 2017-04-26 最終更新日 2018-07-18 実験手法 ELECTRON MICROSCOPY (6.1 Å) 主引用文献 Human CTP synthase filament structure reveals the active enzyme conformation. Nat. Struct. Mol. Biol., 24, 2017
1BXR	STRUCTURE OF CARBAMOYL PHOSPHATE SYNTHETASE COMPLEXED WITH THE ATP ANALOG AMPPNP 分子名称: CARBAMOYL-PHOSPHATE SYNTHASE, CHLORIDE ION, L-ornithine, ... 著者 Thoden, J.B, Wesenberg, G, Raushel, F.M, Holden, H.M. 登録日 1998-10-08 公開日 1999-04-20 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Carbamoyl phosphate synthetase: closure of the B-domain as a result of nucleotide binding. Biochemistry, 38, 1999
5U3C	CryoEM structure of the CTP synthase filament at 4.6 Angstrom resolution 分子名称: ADENOSINE-5'-DIPHOSPHATE, CTP synthase, CYTIDINE-5'-TRIPHOSPHATE 著者 Kollman, J.M, Lynch, E.M. 登録日 2016-12-01 公開日 2017-04-26 最終更新日 2017-06-21 実験手法 ELECTRON MICROSCOPY (4.6 Å) 主引用文献 Human CTP synthase filament structure reveals the active enzyme conformation. Nat. Struct. Mol. Biol., 24, 2017

<123456>