5U03

Cryo-EM structure of the human CTP synthase filament

Summary for 5U03

• Entry DOI: 10.2210/pdb5u03/pdb
• Related: 5U05
• EMDB information: 8474 8475 8476
• Descriptor: CTP synthase 1, ADENOSINE-5'-TRIPHOSPHATE, URIDINE 5'-TRIPHOSPHATE (3 entities in total)
• Functional Keywords: nucleotide metabolism, enzyme, filament, ligase, protein fibril
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 4
• Total formula weight: 271074.48

Authors

Lynch, E.M.,Kollman, J.M. (deposition date: 2016-11-22, release date: 2017-04-26, Last modification date: 2018-07-18)

• Primary citation: Lynch, E.M.,Hicks, D.R.,Shepherd, M.,Endrizzi, J.A.,Maker, A.,Hansen, J.M.,Barry, R.M.,Gitai, Z.,Baldwin, E.P.,Kollman, J.M.; Human CTP synthase filament structure reveals the active enzyme conformation.; Nat. Struct. Mol. Biol., 24:507-514, 2017; PubMed: 28459447; DOI: 10.1038/nsmb.3407

Experimental method

ELECTRON MICROSCOPY (6.1 Å)