1I7S
ANTHRANILATE SYNTHASE FROM SERRATIA MARCESCENS IN COMPLEX WITH ITS END PRODUCT INHIBITOR L-TRYPTOPHAN
Summary for 1I7S
Entry DOI | 10.2210/pdb1i7s/pdb |
Descriptor | ANTHRANILATE SYNTHASE, TRPG, TRYPTOPHAN (3 entities in total) |
Functional Keywords | anthranilate synthase, end product inhibition, tryptophan binding, conformational change, lyase |
Biological source | Serratia marcescens More |
Total number of polymer chains | 4 |
Total formula weight | 157637.23 |
Authors | Spraggon, G.,Kim, C.,Nguyen-Huu, X.,Yee, M.-C.,Yanofsky, C.,Mills, S.E. (deposition date: 2001-03-10, release date: 2001-05-16, Last modification date: 2023-08-09) |
Primary citation | Spraggon, G.,Kim, C.,Nguyen-Huu, X.,Yee, M.C.,Yanofsky, C.,Mills, S.E. The structures of anthranilate synthase of Serratia marcescens crystallized in the presence of (i) its substrates, chorismate and glutamine, and a product, glutamate, and (ii) its end-product inhibitor, L-tryptophan. Proc.Natl.Acad.Sci.USA, 98:6021-6026, 2001 Cited by PubMed: 11371633DOI: 10.1073/pnas.111150298 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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