PDB: 112 件ウェブページステータス検索Chemie searchBIRD

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7XV8	Crystal structure of the Human TR4 DNA-Binding Domain Homodimer Bound to DR1 Response Element 分子名称: DNA (5'-D(*CP*TP*GP*AP*CP*CP*TP*TP*TP*GP*AP*CP*CP*TP*CP*TP*GP*C)-3'), DNA (5'-D(*GP*GP*CP*AP*GP*AP*GP*GP*TP*CP*AP*AP*AP*GP*GP*TP*CP*A)-3'), Nuclear receptor subfamily 2 group C member 2, ... 著者 Liu, Y, Chen, Z. 登録日 2022-05-21 公開日 2022-12-28 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (3.199 Å) 主引用文献 Structures of human TR4LBD-JAZF1 and TR4DBD-DNA complexes reveal the molecular basis of transcriptional regulation. Nucleic Acids Res., 51, 2023
7XV9	Crystal structure of the Human TR4 DNA-Binding Domain 分子名称: Nuclear receptor subfamily 2 group C member 2, ZINC ION 著者 Liu, Y, Chen, Z. 登録日 2022-05-21 公開日 2022-12-28 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.599 Å) 主引用文献 Structures of human TR4LBD-JAZF1 and TR4DBD-DNA complexes reveal the molecular basis of transcriptional regulation. Nucleic Acids Res., 51, 2023
7XVN	Structural basis for DNA recognition feature of retinoid-related orphan receptors 分子名称: DNA (5'-D(P*CP*AP*TP*GP*AP*CP*CP*TP*AP*CP*TP*GP*AP*CP*CP*TP*AP*G)-3'), DNA (5'-D(P*CP*TP*AP*GP*GP*TP*CP*AP*GP*TP*AP*GP*GP*TP*CP*AP*TP*G)-3'), Nuclear receptor ROR-gamma, ... 著者 Chen, Y, Jiang, L. 登録日 2022-05-24 公開日 2023-11-29 最終更新日 2024-04-17 実験手法 X-RAY DIFFRACTION (2.302 Å) 主引用文献 Structural characterization of the DNA binding mechanism of retinoic acid-related orphan receptor gamma. Structure, 32, 2024
8CEF	Asymmetric Dimerization in a Transcription Factor Superfamily is Promoted by Allosteric Interactions with DNA 分子名称: DNA (26-MER), Nuclear receptor DNA binding domain, ZINC ION 著者 Patel, A.K.M, Shaik, T.B, McEwen, A.G, Moras, D, Klaholz, B.P, Billas, I.M.L. 登録日 2023-02-01 公開日 2023-08-09 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.486 Å) 主引用文献 Asymmetric dimerization in a transcription factor superfamily is promoted by allosteric interactions with DNA. Nucleic Acids Res., 51, 2023
8FFV	Cryo-EM structure of the GR-Hsp90-FKBP52 complex 分子名称: ADENOSINE-5'-TRIPHOSPHATE, DEXAMETHASONE, Glucocorticoid receptor, ... 著者 Noddings, C.M, Agard, D.A. 登録日 2022-12-10 公開日 2023-11-01 最終更新日 2023-12-20 実験手法 ELECTRON MICROSCOPY (3.01 Å) 主引用文献 Cryo-EM reveals how Hsp90 and FKBP immunophilins co-regulate the glucocorticoid receptor. Nat.Struct.Mol.Biol., 30, 2023
8FFW	Cryo-EM structure of the GR-Hsp90-FKBP51 complex 分子名称: ADENOSINE-5'-TRIPHOSPHATE, DEXAMETHASONE, Glucocorticoid receptor, ... 著者 Noddings, C.M, Agard, D.A. 登録日 2022-12-10 公開日 2023-11-01 最終更新日 2023-12-20 実験手法 ELECTRON MICROSCOPY (3.23 Å) 主引用文献 Cryo-EM reveals how Hsp90 and FKBP immunophilins co-regulate the glucocorticoid receptor. Nat.Struct.Mol.Biol., 30, 2023
8HBM	Structural basis of the farnesoid X receptor/retinoid X receptor heterodimer on inverted repeat DNA 分子名称: Bile acid receptor, DNA (5'-D(P*CP*CP*GP*AP*GP*GP*TP*CP*AP*AP*TP*GP*AP*CP*CP*TP*CP*G)-3'), DNA (5'-D(P*CP*CP*GP*AP*GP*GP*TP*CP*AP*TP*TP*GP*AP*CP*CP*TP*CP*G)-3'), ... 著者 Jiang, L, Chen, Y. 登録日 2022-10-29 公開日 2023-06-14 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Structural basis of the farnesoid X receptor/retinoid X receptor heterodimer on inverted repeat DNA. Comput Struct Biotechnol J, 21, 2023
8IFO	Crystal structure of estrogen related receptor-gamma DNA binding domain complexed with Pla2g12b promoter 分子名称: DNA (5'-D(*GP*AP*GP*GP*AP*CP*AP*AP*AP*GP*GP*TP*GP*AP*AP*AP*C)-3'), DNA (5'-D(*GP*TP*TP*TP*CP*AP*CP*CP*TP*TP*TP*GP*TP*CP*CP*TP*C)-3'), Estrogen-related receptor gamma, ... 著者 Xu, T, Zhen, X, Liu, J. 登録日 2023-02-19 公開日 2023-03-29 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 ERR gamma-DBD undergoes dimerization and conformational rearrangement upon binding to the downstream site of the DR1 element. Biochem.Biophys.Res.Commun., 656, 2023
8J54	Crystal structure of RXR/DR2 complex 分子名称: DNA (5'-D(*CP*AP*TP*GP*AP*CP*CP*TP*AP*CP*TP*GP*AP*CP*CP*TP*AP*G)-3'), DNA (5'-D(*CP*TP*AP*GP*GP*TP*CP*AP*GP*TP*AP*GP*GP*TP*CP*AP*TP*G)-3'), Retinoic acid receptor RXR, ... 著者 Chen, Y, Jiang, L. 登録日 2023-04-21 公開日 2024-01-17 最終更新日 2024-04-17 実験手法 X-RAY DIFFRACTION (2.72 Å) 主引用文献 Structural characterization of the DNA binding mechanism of retinoic acid-related orphan receptor gamma. Structure, 32, 2024
8PKI	Cryo-EM structure of NR5A2-nucleosome complex SHL+5.5 分子名称: DNA, Histone H2A, Histone H2B type 1-C/E/G, ... 著者 Kobayashi, W, Sappler, A, Bollschweiler, D, Kummecke, M, Basquin, J, Arslantas, E, Ruangroengkulrith, S, Hornberger, R, Duderstadt, K, Tachibana, K. 登録日 2023-06-26 公開日 2024-02-28 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (2.58 Å) 主引用文献 Nucleosome-bound NR5A2 structure reveals pioneer factor mechanism by DNA minor groove anchor competition. Nat.Struct.Mol.Biol., 2024
8RM6	Crystal Structure of Human Androgen Receptor DNA Binding Domain Bound to its Response Element: C3(1)ARE 分子名称: C3(1)ARE_Chain C, C3(1)ARE_Chain D, Isoform 2 of Androgen receptor, ... 著者 Lee, X.Y, Helsen, C, Van Eynde, W, Voet, A, Claessens, F. 登録日 2024-01-05 公開日 2024-04-24 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Structural mechanism underlying variations in DNA binding by the androgen receptor. J.Steroid Biochem.Mol.Biol., 241, 2024
8RM7	Crystal Structure of Human Androgen Receptor DNA Binding Domain Bound to its Response Element: MMTV-177 GRE/ARE 分子名称: Isoform 2 of Androgen receptor, MMTV-177 GRE/ARE Chain C, MMTV-177 GRE/ARE, ... 著者 Lee, X.Y, Helsen, C, Van Eynde, W, Voet, A, Claessens, F. 登録日 2024-01-05 公開日 2024-04-24 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Structural mechanism underlying variations in DNA binding by the androgen receptor. J.Steroid Biochem.Mol.Biol., 241, 2024

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