8IFO

Crystal structure of estrogen related receptor-gamma DNA binding domain complexed with Pla2g12b promoter

Summary for 8IFO

• Entry DOI: 10.2210/pdb8ifo/pdb
• Descriptor: Estrogen-related receptor gamma, DNA (5'-D(*GP*AP*GP*GP*AP*CP*AP*AP*AP*GP*GP*TP*GP*AP*AP*AP*C)-3'), DNA (5'-D(*GP*TP*TP*TP*CP*AP*CP*CP*TP*TP*TP*GP*TP*CP*CP*TP*C)-3'), ... (6 entities in total)
• Functional Keywords: nuclear receptor, err3, pla2g12b, dr1, transcription
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 7
• Total formula weight: 58138.44

Authors

Xu, T.,Zhen, X.,Liu, J. (deposition date: 2023-02-19, release date: 2023-03-29)

• Primary citation: Zhen, X.,Gan, Q.,Qu, L.,Dong, Y.,Pan, C.,Liu, J.,Wang, N.,Xu, T.; ERR gamma-DBD undergoes dimerization and conformational rearrangement upon binding to the downstream site of the DR1 element; Biochem.Biophys.Res.Commun., 656:16-22, 2023; DOI: 10.1016/j.bbrc.2023.03.038

Experimental method

X-RAY DIFFRACTION (2.2 Å)