8IFO

Crystal structure of estrogen related receptor-gamma DNA binding domain complexed with Pla2g12b promoter

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, E (A, B, F)	Estrogen-related receptor gamma	polymer	105	12182.3	3	UniProt (P62508) Pfam (PF00105)	Homo sapiens (human)	ERR gamma-2,Estrogen receptor-related protein 3,Nuclear receptor subfamily 3 group B member 3
2	C, F (C, G)	DNA (5'-D(*GP*AP*GP*GP*AP*CP*AP*AP*AP*GP*GP*TP*GP*AP*AP*AP*C)-3')	polymer	17	5318.5	2		Mus musculus
3	D, G (D, H)	DNA (5'-D(*GP*TP*TP*TP*CP*AP*CP*CP*TP*TP*TP*GP*TP*CP*CP*TP*C)-3')	polymer	17	5095.3	2		Mus musculus
4	H, I, J, K, L... (A, B, F)	ZINC ION	non-polymer		65.4	7	Chemie (ZN)
5	M, N, Q (B, C, F)	MALONATE ION	non-polymer		102.0	3	Chemie (MLI)
6	R, S, T, U, V... (A, B, C, D, F...)	water	water		18.0	87	Chemie (HOH)

Sequence modifications

A, B, F: 123 - 219 (UniProt: P62508)

PDB	External Database	Details
Leu 220	-	expression tag
Glu 221	-	expression tag
His 222	-	expression tag
His 223	-	expression tag
His 224	-	expression tag
His 225	-	expression tag
His 226	-	expression tag
His 227	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	7
	Total formula weight	57374.4
Non-Polymers*	Number of molecules	10
	Total formula weight	764.0
All*	Total formula weight	58138.4

*Water molecules are not included.