8CEF

Asymmetric Dimerization in a Transcription Factor Superfamily is Promoted by Allosteric Interactions with DNA

Summary for 8CEF

Entry DOI	10.2210/pdb8cef/pdb
Descriptor	DNA (26-MER), Nuclear receptor DNA binding domain, ZINC ION, ... (5 entities in total)
Functional Keywords	nuclear receptor, dna, steroid hormone receptor, hormone
Biological source	Mus musculus More
Total number of polymer chains	10
Total formula weight	116929.56
Authors	Patel, A.K.M.,Shaik, T.B.,McEwen, A.G.,Moras, D.,Klaholz, B.P.,Billas, I.M.L. (deposition date: 2023-02-01, release date: 2023-08-09, Last modification date: 2023-09-20)
Primary citation	Patel, A.K.M.,Vilela, P.,Shaik, T.B.,McEwen, A.G.,Hazemann, I.,Brillet, K.,Ennifar, E.,Hamiche, A.,Markov, G.V.,Laudet, V.,Moras, D.,Klaholz, B.P.,Billas, I.M.L. Asymmetric dimerization in a transcription factor superfamily is promoted by allosteric interactions with DNA. Nucleic Acids Res., 51:8864-8879, 2023 Cited by PubMed: 37503845 DOI: 10.1093/nar/gkad632 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.486 Å)

Structure validation