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5AMX
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BU of 5amx by Molmil
Crystal Structure of Proteinase K processed with the CrystalDirect automated mounting and cryo-cooling technology
Descriptor: PROTEINASE K, SULFATE ION
Authors:Zander, U, Hoffmann, G, Cornaciu, I, Cipriani, F, Marquez, J.A.
Deposit date:2015-09-02
Release date:2016-04-13
Last modified:2016-04-20
Method:X-RAY DIFFRACTION (1.01 Å)
Cite:Automated Harvesting and Processing of Protein Crystals Through Laser Photoablation.
Acta Crystallogr.,Sect.D, 72, 2016
4ZOQ
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BU of 4zoq by Molmil
Crystal Structure of a Lanthipeptide Protease
Descriptor: Intracellular serine protease
Authors:Dong, S.H, Nair, S.K.
Deposit date:2015-05-06
Release date:2016-03-23
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Applications of the class II lanthipeptide protease LicP for sequence-specific, traceless peptide bond cleavage.
Chem Sci, 6, 2015
4YN3
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BU of 4yn3 by Molmil
Crystal structure of Cucumisin complex with pro-peptide
Descriptor: CHLORIDE ION, Cucumisin, DI(HYDROXYETHYL)ETHER, ...
Authors:Murayama, K, Kato-Murayama, M, Yokoyama, S, Arima, K, Shirouzu, M.
Deposit date:2015-03-09
Release date:2016-03-09
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural basis of cucumisin protease activity regulation by its propeptide
J. Biochem., 161, 2017
5CW1
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BU of 5cw1 by Molmil
Proteinase K complexed with 4-iodopyrazole
Descriptor: 4-IODOPYRAZOLE, IODIDE ION, Proteinase K, ...
Authors:Bauman, J.D, Arnold, E.
Deposit date:2015-07-27
Release date:2015-12-30
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Rapid experimental SAD phasing and hot spot identification with halogenated fragments
Iucrj, 3, 2016
5AQE
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BU of 5aqe by Molmil
Cooperative bio-metallic selectivity in a tailored protease enables creation of a C-C cross-coupling Heckase
Descriptor: (4-VINYLPHENYL)METHANESULFONIC ACID, CALCIUM ION, CHLORIDE ION, ...
Authors:Sharma, M, Diaz-Rodriguez, A, Offen, W.A, Palm-Espling, M.E, Pordea, A, Wormald, M.R, Mcdonough, M, Davies, G.J, Davis, B.G.
Deposit date:2015-09-22
Release date:2015-10-07
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Bisubstrate Localisation by a Tailored Serine Protease Allows Creation of a Heck-Ase
To be Published
4RYD
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BU of 4ryd by Molmil
X-ray structure of human furin in complex with the competitive inhibitor para-guanidinomethyl-Phac-R-Tle-R-Amba
Descriptor: CALCIUM ION, FORMIC ACID, Furin, ...
Authors:Dahms, S.O, Than, M.E.
Deposit date:2014-12-15
Release date:2015-05-27
Last modified:2015-07-15
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Novel Furin Inhibitors with Potent Anti-infectious Activity.
Chemmedchem, 10, 2015
4ZAR
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BU of 4zar by Molmil
Crystal Structure of Proteinase K from Engyodontium albuminhibited by METHOXYSUCCINYL-ALA-ALA-PRO-PHE-CHLOROMETHYL KETONE at 1.15 A resolution
Descriptor: CALCIUM ION, METHOXYSUCCINYL-ALA-ALA-PRO-PHE-CHLOROMETHYL KETONE, bound form, ...
Authors:Sawaya, M.R, Cascio, D, Collazo, M, Bond, C, Cohen, A, DeNicola, A, Eden, K, Jain, K, Leung, C, Lubock, N, McCormick, J, Rosinski, J, Spiegelman, L, Athar, Y, Tibrewal, N, Winter, J, Solomon, S.
Deposit date:2015-04-14
Release date:2015-05-06
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Crystal Structure of Proteinase K from Engyodontium album inhibited by METHOXYSUCCINYL-ALA-ALA-PRO-PHE-CHLOROMETHYL KETONE at 1.15 A resolution
to be published
3WQB
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BU of 3wqb by Molmil
Crystal structure of aeromonas sobria serine protease (ASP) and the chaperone (ORF2) complex
Descriptor: CALCIUM ION, Extracellular serine protease, Open reading frame 2
Authors:Kobayashi, H, Yoshida, T, Miyakawa, T, Kato, R, Tashiro, M, Yamanaka, H, Tanokura, M, Tsuge, H.
Deposit date:2014-01-24
Release date:2015-03-25
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.41 Å)
Cite:Structural Basis for Action of the External Chaperone for a Propeptide-deficient Serine Protease from Aeromonas sobria.
J.Biol.Chem., 290, 2015
4WOC
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BU of 4woc by Molmil
Proteinase-K Post-Surface Acoustic Waves
Descriptor: Proteinase K, SULFATE ION
Authors:French, J.B.
Deposit date:2014-10-15
Release date:2015-02-18
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.601 Å)
Cite:Precise Manipulation and Patterning of Protein Crystals for Macromolecular Crystallography Using Surface Acoustic Waves.
Small, 11, 2015
4WOB
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BU of 4wob by Molmil
Proteinase-K Pre-Surface Acoustic Wave
Descriptor: Proteinase K, SULFATE ION
Authors:French, J.B.
Deposit date:2014-10-15
Release date:2015-02-18
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Precise Manipulation and Patterning of Protein Crystals for Macromolecular Crystallography Using Surface Acoustic Waves.
Small, 11, 2015
3WIU
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BU of 3wiu by Molmil
Crystal structure of Pro-S324A/L349A
Descriptor: CALCIUM ION, Tk-subtilisin
Authors:Uehara, R, Angkawidjaja, C, Koga, Y, Kanaya, S.
Deposit date:2013-09-25
Release date:2014-10-01
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Requirement of the insertion sequence for activation of Tk-subtilisin
To be Published
3WIV
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BU of 3wiv by Molmil
Crystal structure of Pro-S324A/D356A
Descriptor: CALCIUM ION, Tk-subtilisin
Authors:Uehara, R, Angkawidjaja, C, Koga, Y, Kanaya, S.
Deposit date:2013-09-25
Release date:2014-10-01
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Requirement of the insertion sequence for activation of Tk-subtilisin
To be Published
4TR2
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BU of 4tr2 by Molmil
Crystal structure of PvSUB1
Descriptor: CALCIUM ION, PHOSPHATE ION, Subtilisin-like 1 serine protease
Authors:Giganti, D, Bouillon, A, Martinez, M, Weber, P, Girard-Blanc, C, Petres, S, Haouz, A, Barale, J.C, Alzari, P.M.
Deposit date:2014-06-13
Release date:2014-09-17
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:A novel Plasmodium-specific prodomain fold regulates the malaria drug target SUB1 subtilase.
Nat Commun, 5, 2014
4NE9
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BU of 4ne9 by Molmil
PCSK9 in complex with LDLR peptide
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Low-density lipoprotein receptor, ...
Authors:Liu, S.
Deposit date:2013-10-28
Release date:2014-09-10
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Design and synthesis of truncated EGF-A peptides that restore LDL-R recycling in the presence of PCSK9 in vitro.
Chem.Biol., 21, 2014
4C3U
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BU of 4c3u by Molmil
Extensive counter-ion interactions with subtilisin in aqueous medium, Cs derivative
Descriptor: CALCIUM ION, CESIUM ION, CHLORIDE ION, ...
Authors:Cianci, M, Negroni, J, Helliwell, J.R, Halling, P.J.
Deposit date:2013-08-27
Release date:2014-08-20
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Extensive Counter-Ion Interactions Seen at the Surface of Subtilisin in an Aqueous Medium
Rsc Adv, 2014
4C3V
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BU of 4c3v by Molmil
Extensive counter-ion interactions with subtilisin in aqueous medium, no Cs soak
Descriptor: CALCIUM ION, SODIUM ION, SUBTILISIN CARLSBERG, ...
Authors:Cianci, M, Negroni, J, Helliwell, J.R, Halling, P.J.
Deposit date:2013-08-27
Release date:2014-08-20
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Extensive Counter-Ion Interactions Seen at the Surface of Subtilisin in an Aqueous Medium
Rsc Adv, 2014
4OV6
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BU of 4ov6 by Molmil
Crystal structure of PCSK9(53-451) with Adnectin
Descriptor: 1,2-ETHANEDIOL, Adnectin, Proprotein convertase subtilisin/kexin type 9, ...
Authors:Khan, J.A.
Deposit date:2014-02-20
Release date:2014-07-02
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:Pharmacologic Profile of the Adnectin BMS-962476, a Small Protein Biologic Alternative to PCSK9 Antibodies for Low-Density Lipoprotein Lowering.
J.Pharmacol.Exp.Ther., 350, 2014
4MZD
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BU of 4mzd by Molmil
High resolution crystal structure of the nisin leader peptidase NisP from Lactococcus lactis
Descriptor: Nisin leader peptide-processing serine protease NisP
Authors:Rao, Z.H, Xu, Y.Y, Li, X, Yang, W.
Deposit date:2013-09-30
Release date:2014-06-11
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Structure of the nisin leader peptidase NisP revealing a C-terminal autocleavage activity.
Acta Crystallogr.,Sect.D, 70, 2014
4LVO
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BU of 4lvo by Molmil
Crystal structure of PfSUB1-prodomain-NIMP.M7 Fab complex with added CaCl2
Descriptor: CALCIUM ION, NIMP.M7 Fab heavy chain, NIMP.M7 Fab light chain, ...
Authors:Withers-Martinez, C, Blackman, M.J.
Deposit date:2013-07-26
Release date:2014-05-07
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:The malaria parasite egress protease SUB1 is a calcium-dependent redox switch subtilisin.
Nat Commun, 5, 2014
4LVN
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BU of 4lvn by Molmil
Crystal structure of PfSUB1-prodomain-NIMP.M7 Fab complex
Descriptor: CALCIUM ION, NICKEL (II) ION, NIMP.M7 Fab heavy chain, ...
Authors:Withers-Martinez, C, Blackman, M.J.
Deposit date:2013-07-26
Release date:2014-05-07
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:The malaria parasite egress protease SUB1 is a calcium-dependent redox switch subtilisin.
Nat Commun, 5, 2014
4CFY
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BU of 4cfy by Molmil
SAVINASE CRYSTAL STRUCTURES FOR COMBINED SINGLE CRYSTAL DIFFRACTION AND POWDER DIFFRACTION ANALYSIS
Descriptor: CALCIUM ION, SODIUM ION, SUBTILISIN SAVINASE
Authors:Frankaer, C.G, Moroz, O.V, Turkenburg, J.P, Aspmo, S.I, Thymark, M, Friis, E.P, Stahla, K, Nielsen, J.E, Wilson, K.S, Harris, P.
Deposit date:2013-11-19
Release date:2014-04-09
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.17 Å)
Cite:Analysis of an Industrial Production Suspension of Bacillus Lentus Subtilisin Crystals by Powder Diffraction: A Powerful Quality-Control Tool.
Acta Crystallogr.,Sect.D, 70, 2014
4OMC
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BU of 4omc by Molmil
X-ray structure of human furin in complex with the competitive inhibitor meta-guanidinomethyl-Phac-RVR-Amba
Descriptor: CALCIUM ION, FORMIC ACID, Furin, ...
Authors:Dahms, S.O, Than, M.E.
Deposit date:2014-01-27
Release date:2014-04-09
Last modified:2014-05-28
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:X-ray Structures of Human Furin in Complex with Competitive Inhibitors.
Acs Chem.Biol., 9, 2014
4CG0
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BU of 4cg0 by Molmil
Savinase crystal structures for combined single crystal diffraction and powder diffraction analysis
Descriptor: CALCIUM ION, SODIUM ION, SUBTILISIN SAVINASE
Authors:Frankaer, C.G, Moroz, O.V, Turkenburg, J.P, Aspmo, S.I, Thymark, M, Friis, E.P, Stahla, K, Nielsen, J.E, Wilson, K.S, Harris, P.
Deposit date:2013-11-19
Release date:2014-04-09
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.36 Å)
Cite:Analysis of an Industrial Production Suspension of Bacillus Lentus Subtilisin Crystals by Powder Diffraction: A Powerful Quality-Control Tool.
Acta Crystallogr.,Sect.D, 70, 2014
4OMD
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BU of 4omd by Molmil
X-ray structure of human furin in complex with the competitive inhibitor Phac-RVR-Amba
Descriptor: CALCIUM ION, FORMIC ACID, Furin, ...
Authors:Dahms, S.O, Than, M.E.
Deposit date:2014-01-27
Release date:2014-04-09
Last modified:2014-05-28
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:X-ray Structures of Human Furin in Complex with Competitive Inhibitors.
Acs Chem.Biol., 9, 2014
4CFZ
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BU of 4cfz by Molmil
SAVINASE CRYSTAL STRUCTURES FOR COMBINED SINGLE CRYSTAL DIFFRACTION AND POWDER DIFFRACTION ANALYSIS
Descriptor: CALCIUM ION, SODIUM ION, SUBTILISIN SAVINASE, ...
Authors:Frankaer, C.G, Moroz, O.V, Turkenburg, J.P, Aspmo, S.I, Thymark, M, Friis, E.P, Stahla, K, Nielsen, J.E, Wilson, K.S, Harris, P.
Deposit date:2013-11-19
Release date:2014-04-09
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Analysis of an Industrial Production Suspension of Bacillus Lentus Subtilisin Crystals by Powder Diffraction: A Powerful Quality-Control Tool.
Acta Crystallogr.,Sect.D, 70, 2014

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