2VDX
 
 | |
2VH4
 | | Structure of a loop C-sheet serpin polymer | | Descriptor: | TENGPIN | | Authors: | Zhang, Q, Law, R.H.P, Bottomley, S.P, Whisstock, J.C, Buckle, A.M. | | Deposit date: | 2007-11-19 | | Release date: | 2008-01-08 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | A Structural Basis for Loop C-Sheet Polymerization in Serpins.
J.Mol.Biol., 376, 2008
|
|
2V95
 | | Structure of Corticosteroid-Binding Globulin in complex with Cortisol | | Descriptor: | (11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione, CORTICOSTEROID-BINDING GLOBULIN | | Authors: | Klieber, M.A, Muller, Y.A. | | Deposit date: | 2007-08-21 | | Release date: | 2007-09-04 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.93 Å) | | Cite: | Corticosteroid-Binding Globulin: Structural Basis for Steroid Transport and Proteinase-Triggered Release
J.Biol.Chem., 282, 2007
|
|
2VDY
 | | Crystal structure of the reactive loop cleaved Corticosteroid Binding Globulin complexed with Cortisol | | Descriptor: | (11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione, CORTICOSTEROID-BINDING GLOBULIN | | Authors: | Zhou, A, Wei, Z, Read, R.J. | | Deposit date: | 2007-10-13 | | Release date: | 2008-05-13 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | The S-to-R Transition of Corticosteroid-Binding Globulin and the Mechanism of Hormone Release.
J.Mol.Biol., 380, 2008
|
|
2WY1
 | |
2WXW
 | |
2WXX
 | |
2WXY
 | | Crystal structure of mouse angiotensinogen in the reduced form | | Descriptor: | 1,2-ETHANEDIOL, ANGIOTENSINOGEN, SODIUM ION | | Authors: | Zhou, A, Wei, Z, Carrell, R.W, Read, R.J. | | Deposit date: | 2009-11-11 | | Release date: | 2010-10-20 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | A Redox Switch in Angiotensinogen Modulates Angiotensin Release.
Nature, 468, 2010
|
|
2WY0
 | | Crystal structure of mouse angiotensinogen in the oxidised form with space group P6122 | | Descriptor: | 1,2-ETHANEDIOL, ANGIOTENSINOGEN, SODIUM ION | | Authors: | Zhou, A, Wei, Z, Carrell, R.W, Read, R.J. | | Deposit date: | 2009-11-11 | | Release date: | 2010-10-20 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.38 Å) | | Cite: | A Redox Switch in Angiotensinogen Modulates Angiotensin Release.
Nature, 468, 2010
|
|
2WXZ
 | |
2XN6
 | | Crystal structure of thyroxine-binding globulin complexed with thyroxine-fluoresein | | Descriptor: | 1,2-ETHANEDIOL, 3',6'-DIHYDROXY-3-OXO-3H-SPIRO[2-BENZOFURAN-1,9'-XANTHENE]-6-CARBOXYLIC ACID, 3,5,3',5'-TETRAIODO-L-THYRONINE, ... | | Authors: | Qi, X, Yan, Y, Wei, Z, Zhou, A. | | Deposit date: | 2010-07-30 | | Release date: | 2011-02-16 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.29 Å) | | Cite: | Allosteric Modulation of Hormone Release from Thyroxine and Corticosteroid Binding-Globulins.
J.Biol.Chem., 286, 2011
|
|
2XN7
 | | Crystal structure of thyroxine-binding globulin complexed with thyroxine-fluoresein (T405-CF) | | Descriptor: | 1,2-ETHANEDIOL, 3',6'-DIHYDROXY-3-OXO-3H-SPIRO[2-BENZOFURAN-1,9'-XANTHENE]-5-CARBOXYLIC ACID, 3,5,3',5'-TETRAIODO-L-THYRONINE, ... | | Authors: | Qi, X, Yan, Y, Wei, Z, Zhou, A. | | Deposit date: | 2010-07-30 | | Release date: | 2011-02-16 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.43 Å) | | Cite: | Allosteric Modulation of Hormone Release from Thyroxine and Corticosteroid Binding-Globulins.
J.Biol.Chem., 286, 2011
|
|
2XN3
 | | Crystal structure of thyroxine-binding globulin complexed with mefenamic acid | | Descriptor: | 2-[(2,3-DIMETHYLPHENYL)AMINO]BENZOIC ACID, THYROXINE-BINDING GLOBULIN | | Authors: | Qi, X, Yan, Y, Wei, Z, Zhou, A. | | Deposit date: | 2010-07-30 | | Release date: | 2011-02-16 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.09 Å) | | Cite: | Allosteric Modulation of Hormone Release from Thyroxine and Corticosteroid Binding-Globulins.
J.Biol.Chem., 286, 2011
|
|
2XN5
 | | Crystal structure of thyroxine-binding globulin complexed with Furosemide | | Descriptor: | 1,2-ETHANEDIOL, 5-(AMINOSULFONYL)-4-CHLORO-2-[(2-FURYLMETHYL)AMINO]BENZOIC ACID, CALCIUM ION, ... | | Authors: | Qi, X, Yan, Y, Wei, Z, Zhou, A. | | Deposit date: | 2010-07-30 | | Release date: | 2011-02-16 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Allosteric Modulation of Hormone Release from Thyroxine and Corticosteroid Binding-Globulins.
J.Biol.Chem., 286, 2011
|
|
1A7C
 | | HUMAN PLASMINOGEN ACTIVATOR INHIBITOR TYPE-1 IN COMPLEX WITH A PENTAPEPTIDE | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-D-ribopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, PENTAPEPTIDE, ... | | Authors: | Xue, Y, Inghardt, T, Sjolin, L, Deinum, J. | | Deposit date: | 1998-03-12 | | Release date: | 1999-03-23 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Interfering with the inhibitory mechanism of serpins: crystal structure of a complex formed between cleaved plasminogen activator inhibitor type 1 and a reactive-centre loop peptide
Structure, 6, 1998
|
|
1ANT
 | |
1B3K
 | | Plasminogen activator inhibitor-1 | | Descriptor: | PLASMINOGEN ACTIVATOR INHIBITOR-1 | | Authors: | Sharp, A.M, Stein, P.E, Pannu, N.S, Read, R.J. | | Deposit date: | 1998-12-11 | | Release date: | 1999-12-11 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.99 Å) | | Cite: | The active conformation of plasminogen activator inhibitor 1, a target for drugs to control fibrinolysis and cell adhesion.
Structure Fold.Des., 7, 1999
|
|
1ATH
 | |
1ATU
 | | UNCLEAVED ALPHA-1-ANTITRYPSIN | | Descriptor: | ALPHA-1-ANTITRYPSIN | | Authors: | Ryu, S.-E, Choi, H.-J. | | Deposit date: | 1997-05-11 | | Release date: | 1997-08-20 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | The native strains in the hydrophobic core and flexible reactive loop of a serine protease inhibitor: crystal structure of an uncleaved alpha1-antitrypsin at 2.7 A.
Structure, 4, 1996
|
|
1ATT
 | |
1AZX
 | | ANTITHROMBIN/PENTASACCHARIDE COMPLEX | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 3,4-di-O-methyl-2,6-di-O-sulfo-alpha-D-glucopyranose-(1-4)-2,3-di-O-methyl-beta-D-glucopyranuronic acid-(1-4)-2,3,6-tri-O-sulfo-alpha-D-glucopyranose-(1-4)-3-O-methyl-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-methyl 2,3,6-tri-O-sulfo-alpha-D-glucopyranoside, ANTITHROMBIN | | Authors: | Jin, L, Abrahams, J.P, Skinner, R, Petitou, M, Pike, R.N, Carrell, R.W. | | Deposit date: | 1997-11-23 | | Release date: | 1999-01-13 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | The anticoagulant activation of antithrombin by heparin.
Proc.Natl.Acad.Sci.USA, 94, 1997
|
|
1AS4
 | | CLEAVED ANTICHYMOTRYPSIN A349R | | Descriptor: | ACETATE ION, ANTICHYMOTRYPSIN | | Authors: | Lukacs, C.M, Christianson, D.W. | | Deposit date: | 1997-08-12 | | Release date: | 1998-02-25 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Engineering an anion-binding cavity in antichymotrypsin modulates the "spring-loaded" serpin-protease interaction.
Biochemistry, 37, 1998
|
|
1BR8
 | | IMPLICATIONS FOR FUNCTION AND THERAPY OF A 2.9A STRUCTURE OF BINARY-COMPLEXED ANTITHROMBIN | | Descriptor: | PROTEIN (ANTITHROMBIN-III), PROTEIN (PEPTIDE) | | Authors: | Skinner, R, Chang, W.S.W, Jin, L, Pei, X.Y, Huntington, J.A, Abrahams, J.P, Carrell, R.W, Lomas, D.A. | | Deposit date: | 1998-08-26 | | Release date: | 1998-09-02 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Implications for function and therapy of a 2.9 A structure of binary-complexed antithrombin.
J.Mol.Biol., 283, 1998
|
|
1BY7
 | |
1C5G
 | | PLASMINOGEN ACTIVATOR INHIBITOR-1 | | Descriptor: | PLASMINOGEN ACTIVATOR INHIBITOR-1 | | Authors: | Goldsmith, E.J. | | Deposit date: | 1999-12-07 | | Release date: | 1999-12-17 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Engineering of plasminogen activator inhibitor-1 to reduce the rate of latency transition.
Nat.Struct.Biol., 2, 1995
|
|
