2V95

Structure of Corticosteroid-Binding Globulin in complex with Cortisol

Replaces:  2V6D

Summary for 2V95

• Entry DOI: 10.2210/pdb2v95/pdb
• Descriptor: CORTICOSTEROID-BINDING GLOBULIN, (11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione (3 entities in total)
• Functional Keywords: transport protein, cbg, rcl, serpin, secreted, transport, glycoprotein, lipid-binding, glucocorticoids, steroid-binding, steroid transporter, corticosteroid-binding globulin transport protein
• Biological source: RATTUS NORVEGICUS (RAT)
• Cellular location: Secreted: P31211
• Total number of polymer chains: 1
• Total formula weight: 42251.92

Authors

Klieber, M.A.,Muller, Y.A. (deposition date: 2007-08-21, release date: 2007-09-04, Last modification date: 2023-12-13)

• Primary citation: Klieber, M.A.,Underhill, C.,Hammond, G.L.,Muller, Y.A.; Corticosteroid-Binding Globulin: Structural Basis for Steroid Transport and Proteinase-Triggered Release; J.Biol.Chem., 282:29594-, 2007; PubMed: 17644521; DOI: 10.1074/JBC.M705014200

Experimental method

X-RAY DIFFRACTION (1.93 Å)