2V95

Structure of Corticosteroid-Binding Globulin in complex with Cortisol

Replaces:  2V6D

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	CORTICOSTEROID-BINDING GLOBULIN	polymer	371	41889.5	1	UniProt (P31211) Pfam (PF00079) In PDB	RATTUS NORVEGICUS (RAT)	CBG, TRANSCORTIN, SERPIN A6
2	A	(11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione	non-polymer		362.5	1	Chemie (HCY)
3		water	water		18.0	174	Chemie (HOH)

Sequence modifications

A: 4 - 4 (PDB: 2V95)
A: 5 - 374 (UniProt: P31211)

PDB	External Database	Details
Asn 141	Thr 163	engineered mutation
Gln 142	Arg 164	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	41889.5
Non-Polymers*	Number of molecules	1
	Total formula weight	362.5
All*	Total formula weight	42251.9

*Water molecules are not included.