2V95

Structure of Corticosteroid-Binding Globulin in complex with Cortisol

Replaces:  2V6D

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	CORTICOSTEROID-BINDING GLOBULIN	polymer	371	41889.5	1	UniProt (P31211) Pfam (PF00079)	RATTUS NORVEGICUS (RAT)	CBG, TRANSCORTIN, SERPIN A6
2	B (A)	(11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione	non-polymer		362.5	1	Chemie (HCY) PubChem (16757875) PubChem (16760505) PubChem (17749280) PubChem (18635646) PubChem (3640) PubChem (5754) PubChem (176519891) PubChem (22841298) PubChem (108888) PubChem (23766831) PubChem (16401107) PubChem (24867549) PubChem (40469544) PubChem (40469545) PubChem (40488894) PubChem (40543465) PubChem (40543468) PubChem (40543471) PubChem (40543474) PubChem (40776161) PubChem (44656583) PubChem (1768391) PubChem (1768392) PubChem (1768390) PubChem (46885418) PubChem (46907807) PubChem (657311) PubChem (50987195) PubChem (50987424) PubChem (969496) PubChem (56614803) PubChem (56635598) PubChem (1350204) PubChem (57232608) PubChem (3246033) PubChem (57536781) PubChem (59582250) PubChem (60111544) PubChem (5320346) PubChem (6603869) PubChem (6713680) PubChem (229860) PubChem (7048969) PubChem (7067813) PubChem (89693181) PubChem (8015711) PubChem (11279933) PubChem (1403277) PubChem (11869394) PubChem (11869395) PubChem (11869396) PubChem (12304007) PubChem (12304008) PubChem (12304009) PubChem (12304012) PubChem (12304023) PubChem (6336184) PubChem (101739542) PubChem (6981543) PubChem (7059531) PubChem (122664736) PubChem (12304018) PubChem (124351407) PubChem (124404247) PubChem (124514954) PubChem (124746079) PubChem (125037485) PubChem (129009993) PubChem (129010215) PubChem (132012242) PubChem (154825154) PubChem (159059490) PubChem (162927257) PubChem (162927258) PubChem (165944364) PubChem (166480825) PubChem (169428820) PubChem (172400002) PubChem (172873892) PubChem (173540535)
3	C (A)	water	water		18.0	174	Chemie (HOH)

Sequence modifications

A: 4 - 4 (PDB: 2V95)
A: 5 - 374 (UniProt: P31211)

PDB	External Database	Details
Asn 141	Thr 163	engineered mutation
Gln 142	Arg 164	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	41889.5
Non-Polymers*	Number of molecules	1
	Total formula weight	362.5
All*	Total formula weight	42251.9

*Water molecules are not included.