1A7C

HUMAN PLASMINOGEN ACTIVATOR INHIBITOR TYPE-1 IN COMPLEX WITH A PENTAPEPTIDE

Summary for 1A7C

DescriptorPLASMINOGEN ACTIVATOR INHIBITOR TYPE 1, PENTAPEPTIDE, RIBOSE(PYRANOSE FORM), ... (5 entities in total)
Functional Keywordsserine protease inhibitor, pai-1, carbohydrate, inhibitor complex, protease inhibitor-peptide complex, hydrolase inhibitor-peptide complex, hydrolase inhibitor/peptide
Biological sourceHomo sapiens (human)
Cellular locationSecreted P05121
Total number of polymer chains3
Total molecular weight44665.91
Authors
Xue, Y.,Inghardt, T.,Sjolin, L.,Deinum, J. (deposition date: 1998-03-12, release date: 1999-03-23, Last modification date: 2012-02-29)
Primary citation
Xue, Y.,Bjorquist, P.,Inghardt, T.,Linschoten, M.,Musil, D.,Sjolin, L.,Deinum, J.
Interfering with the inhibitory mechanism of serpins: crystal structure of a complex formed between cleaved plasminogen activator inhibitor type 1 and a reactive-centre loop peptide
Structure, 6:627-636, 1998
PubMed: 9634700 (PDB entries with the same primary citation)
DOI: 10.1016/S0969-2126(98)00064-1
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.95 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliers202.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

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