2VDX

Crystal Structure of the reactive loop Cleaved Corticosteroid Binding Globulin

Summary for 2VDX

• Entry DOI: 10.2210/pdb2vdx/pdb
• Related: 2VDY
• Descriptor: CORTICOSTEROID-BINDING GLOBULIN, SODIUM ION (3 entities in total)
• Functional Keywords: transport protein, cortisol binding globulin, glycoprotein, lipid-binding, steroid-binding, disease mutation, cbg, serpin, cleaved, secreted, cortisol
• Biological source: HOMO SAPIENS (HUMAN)
• Cellular location: Secreted: P08185
• Total number of polymer chains: 2
• Total formula weight: 83463.14

Authors

Zhou, A.,Wei, Z.,Read, R.J. (deposition date: 2007-10-13, release date: 2008-05-06, Last modification date: 2023-12-13)

• Primary citation: Zhou, A.,Wei, Z.,Stanley, P.L.,Read, R.J.,Stein, P.E.,Carrell, R.W.; The S-to-R Transition of Corticosteroid-Binding Globulin and the Mechanism of Hormone Release.; J.Mol.Biol., 380:244-, 2008; PubMed: 18513745; DOI: 10.1016/J.JMB.2008.05.012

Experimental method

X-RAY DIFFRACTION (1.84 Å)