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2VDX

Crystal Structure of the reactive loop Cleaved Corticosteroid Binding Globulin

Functional Information from GO Data
ChainGOidnamespacecontents
A0004867molecular_functionserine-type endopeptidase inhibitor activity
A0005496molecular_functionsteroid binding
A0005576cellular_componentextracellular region
A0005615cellular_componentextracellular space
A0008211biological_processglucocorticoid metabolic process
A0070062cellular_componentextracellular exosome
B0004867molecular_functionserine-type endopeptidase inhibitor activity
B0005496molecular_functionsteroid binding
B0005576cellular_componentextracellular region
B0005615cellular_componentextracellular space
B0008211biological_processglucocorticoid metabolic process
B0070062cellular_componentextracellular exosome
Functional Information from PDB Data
site_idAC1
Number of Residues6
DetailsBINDING SITE FOR RESIDUE NA A1384
ChainResidue
ATYR235
AGLY237
AHOH2058
AHOH2098
AHOH2099
AHOH2101

site_idAC2
Number of Residues4
DetailsBINDING SITE FOR RESIDUE NA A1385
ChainResidue
AHOH2084
ASER215
ASER216
AHOH2079

site_idAC3
Number of Residues5
DetailsBINDING SITE FOR RESIDUE NA B1384
ChainResidue
BTYR235
BGLY237
BHOH2023
BHOH2085
BHOH2086

site_idAC4
Number of Residues3
DetailsBINDING SITE FOR RESIDUE NA A1386
ChainResidue
ALEU93
ALYS96
AHOH2029

Functional Information from PROSITE/UniProt
site_idPS00284
Number of Residues11
DetailsSERPIN Serpins signature. LRFNQPFIImI
ChainResidueDetails
ALEU355-ILE365

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues6
DetailsBINDING: BINDING => ECO:0000269|PubMed:18513745, ECO:0007744|PDB:2VDY
ChainResidueDetails
AGLN232
AASN264
AHIS368
BGLN232
BASN264
BHIS368

site_idSWS_FT_FI2
Number of Residues2
DetailsBINDING:
ChainResidueDetails
ATRP371
BTRP371

site_idSWS_FT_FI3
Number of Residues2
DetailsSITE: Conserved cysteine within steroid binding domain
ChainResidueDetails
ACYS228
BCYS228

site_idSWS_FT_FI4
Number of Residues2
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:14760718, ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:19159218
ChainResidueDetails
AASN74
BASN74

site_idSWS_FT_FI5
Number of Residues2
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255
ChainResidueDetails
AASN154
BASN154

site_idSWS_FT_FI6
Number of Residues2
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine
ChainResidueDetails
AASN238
BASN238

site_idSWS_FT_FI7
Number of Residues2
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:19159218
ChainResidueDetails
AASN308
BASN308

site_idSWS_FT_FI8
Number of Residues2
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:16335952
ChainResidueDetails
AILE347
BILE347

226707

PDB entries from 2024-10-30

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