PDB: 1371 件ウェブページステータス検索Chemie searchBIRD

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1BU7	CRYOGENIC STRUCTURE OF CYTOCHROME P450BM-3 HEME DOMAIN 分子名称: 1,2-ETHANEDIOL, PROTEIN (CYTOCHROME P450), PROTOPORPHYRIN IX CONTAINING FE 著者 Li, H, Poulos, T.L. 登録日 1998-09-14 公開日 1998-09-23 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Structure of a cytochrome P450-redox partner electron-transfer complex. Proc.Natl.Acad.Sci.USA, 96, 1999
8Q5J	Cytochrome P450 monooxygenase from Streptomyces scabiei (SscaCYP) 分子名称: Cytochrome P450 107B1, MAGNESIUM ION, PROTOPORPHYRIN IX CONTAINING FE 著者 Opperman, D.J, Ebrecht, A.C. 登録日 2023-08-09 公開日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.48 Å) 主引用文献 Natural alternative heme-environments allow efficient peroxygenase activity by cytochrome P450 monooxygenases Catalysis Science And Technology, 13, 2023
8SBI	Crystal structure of human sterol 14 alpha-demethylase (CYP51) in the ligand-free state 分子名称: Lanosterol 14-alpha demethylase, PROTOPORPHYRIN IX CONTAINING FE 著者 Hargrove, T.Y, Wawrzak, Z, Lepesheva, G.I. 登録日 2023-04-03 公開日 2023-04-12 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.73 Å) 主引用文献 Structural dynamics of sterol 14 alpha demethylases upon catalysis To Be Published
2L8M	Reduced and CO-bound cytochrome P450cam (CYP101A1) 分子名称: CAMPHOR, CARBON MONOXIDE, CHLORIDE ION, ... 著者 Pochapsky, T.C, Pochapsky, S.S, Dang, M, Asciutto, E, Madura, J. 登録日 2011-01-19 公開日 2011-02-16 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Experimentally Restrained Molecular Dynamics Simulations for Characterizing the Open States of Cytochrome P450(cam). Biochemistry, 50, 2011
1C8J	CRYSTAL STRUCTURE OF CYTOCHROME P450CAM MUTANT (F87W/Y96F) 分子名称: CYTOCHROME P450-CAM, PROTOPORPHYRIN IX CONTAINING FE 著者 Liu, Y, Jiang, F, Guo, Q, Chen, X, Jin, J, Sun, Y, Rao, Z. 登録日 2000-05-31 公開日 2001-05-09 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal Structure of Cytochrome P450cam mutant (F87W/Y96F) To be Published
8SO2	Human CYP3A4 bound to a substrate 分子名称: CAFFEINE, Cytochrome P450 3A4, PROTOPORPHYRIN IX CONTAINING FE 著者 Sevrioukova, I.F. 登録日 2023-04-28 公開日 2023-08-02 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Interaction of CYP3A4 with caffeine: First insights into multiple substrate binding. J.Biol.Chem., 299, 2023
8SO1	Human CYP3A4 bound to three caffeine molecules 分子名称: CAFFEINE, Cytochrome P450 3A4, PROTOPORPHYRIN IX CONTAINING FE 著者 Sevrioukova, I.F. 登録日 2023-04-28 公開日 2023-08-02 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Interaction of CYP3A4 with caffeine: First insights into multiple substrate binding. J.Biol.Chem., 299, 2023
8SPP	Crystal structure of a heme enzyme RufO in rufomycin biosynthesis 分子名称: Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE 著者 Wang, Y, Jordan, S, Li, B. 登録日 2023-05-03 公開日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 Structural and spectroscopic characterization of RufO indicates a new biological role in rufomycin biosynthesis. J.Biol.Chem., 299, 2023
2LQD	Reduced and CO-bound cytochrome P450cam (CYP101A1) 分子名称: CARBON MONOXIDE, Camphor 5-monooxygenase, POTASSIUM ION, ... 著者 Pochapsky, T.C, Pochapsky, S.S, Asciutto, E, Madura, J, Young, M.J. 登録日 2012-03-02 公開日 2012-05-09 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Solution Structural Ensembles of Substrate-Free Cytochrome P450(cam). Biochemistry, 51, 2012
8SPD	Cytochrome P450 (CYP) 3A4 crystallized with clotrimazole 分子名称: 1-[(2-CHLOROPHENYL)(DIPHENYL)METHYL]-1H-IMIDAZOLE, Cytochrome P450 3A4, PROTOPORPHYRIN IX CONTAINING FE 著者 Hsu, M.H, Johnson, E.F. 登録日 2023-05-02 公開日 2023-10-11 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Differential Effects of Clotrimazole on X-Ray Crystal Structures of Human Cytochromes P450 3A5 and 3A4. Drug Metab.Dispos., 51, 2023
8SG5	Cytochrome P450 (CYP) 3A5 crystallized with clotrimazole 分子名称: 1-[(2-CHLOROPHENYL)(DIPHENYL)METHYL]-1H-IMIDAZOLE, Cytochrome P450 3A5, DODECYL NONA ETHYLENE GLYCOL ETHER, ... 著者 Hsu, M.H, Johnson, E.F. 登録日 2023-04-11 公開日 2023-10-11 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Differential Effects of Clotrimazole on X-Ray Crystal Structures of Human Cytochromes P450 3A5 and 3A4. Drug Metab.Dispos., 51, 2023
8SPC	Crystal structure of the cytochrome P450 enzyme RufO 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Cytochrome P450, ... 著者 Dratch, B.D, Davis, K.M. 登録日 2023-05-02 公開日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.871 Å) 主引用文献 Insights into Substrate Recognition by the Unusual Nitrating Enzyme RufO. Acs Chem.Biol., 18, 2023
8SS0	Human sterol 14 alpha-demethylase (CYP51) in complex with the reaction intermediate 14 alpha-aldehyde dihydrolanosterol 分子名称: 3beta-hydroxy-10alpha,13alpha-lanosta-8,24-dien-30-al, Lanosterol 14-alpha demethylase, PROTOPORPHYRIN IX CONTAINING FE 著者 Hargrove, T.Y, Wawrzak, Z, Guengerich, F.P, Lepesheva, G.I. 登録日 2023-05-08 公開日 2024-01-17 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Oxygen-18 Labeling Reveals a Mixed Fe-O Mechanism in the Last Step of Cytochrome P450 51 Sterol 14 alpha-Demethylation. Angew.Chem.Int.Ed.Engl., 63, 2024
8QZE	Heme-domain BM3 variant 21B3_F87V-A328F 分子名称: Bifunctional cytochrome P450/NADPH--P450 reductase, GLYCEROL, IMIDAZOLE, ... 著者 Opperman, D.J, Ebrecht, A.C, Aschenbrenner, J.C. 登録日 2023-10-27 公開日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 Revisiting strategies and their combinatorial effect for introducing peroxygenase activity in CYP102A1 (P450BM3) Mol Catal, 557, 2024
8QZF	Heme-domain BM3 mutant T268E 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Bifunctional cytochrome P450/NADPH--P450 reductase, DI(HYDROXYETHYL)ETHER, ... 著者 Opperman, D.J, Ebrecht, A.C, Aschenbrenner, J.C. 登録日 2023-10-27 公開日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Revisiting strategies and their combinatorial effect for introducing peroxygenase activity in CYP102A1 (P450BM3) Mol Catal, 557, 2024
1CMJ	CRYSTAL STRUCTURES OF FERRIC-NO COMPLEXES OF FUNGAL NITRIC OXIDE REDUCTASE AND THEIR SER286 MUTANTS AT CRYOGENIC TEMPERATURE 分子名称: CYTOCHROME P450, NITRIC OXIDE, PROTOPORPHYRIN IX CONTAINING FE 著者 Park, S.-Y, Shiro, Y. 登録日 1999-05-07 公開日 2000-03-22 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Proton delivery in NO reduction by fungal nitric-oxide reductase. Cryogenic crystallography, spectroscopy, and kinetics of ferric-NO complexes of wild-type and mutant enzymes. J.Biol.Chem., 275, 2000
1CL6	CRYSTAL STRUCTURES OF FERRIC-NO COMPLEXES OF FUNGAL NITRIC OXIDE REDUCTASE AND ITS SER286 MUTANTS AT CRYOGENIC TEMPERATURE 分子名称: CYTOCHROME P450, NITRIC OXIDE, PROTOPORPHYRIN IX CONTAINING FE 著者 Park, S.-Y, Shiro, Y. 登録日 1999-05-06 公開日 2000-03-22 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Proton delivery in NO reduction by fungal nitric-oxide reductase. Cryogenic crystallography, spectroscopy, and kinetics of ferric-NO complexes of wild-type and mutant enzymes. J.Biol.Chem., 275, 2000
1CP4	FORMATION, CRYSTAL STRUCTURE, AND REARRANGEMENT OF A CYTOCHROME P450-CAM IRON-PHENYL COMPLEX 分子名称: BENZENE, CYTOCHROME P450-CAM, PROTOPORPHYRIN IX CONTAINING FE 著者 Raag, R, Poulos, T.L. 登録日 1991-06-04 公開日 1993-01-15 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Formation, crystal structure, and rearrangement of a cytochrome P-450cam iron-phenyl complex. Biochemistry, 29, 1990
1CMN	CRYSTAL STRUCTURES OF FERRIC-NO COMPLEXES OF FUNGAL NITRIC OXIDE REDUCTASE AND THEIR SER286 MUTANTS AT CRYOGENIC TEMPERATURE 分子名称: CYTOCHROME P450, NITRIC OXIDE, PROTOPORPHYRIN IX CONTAINING FE 著者 Park, S.-Y, Shiro, Y. 登録日 1999-05-07 公開日 2000-03-22 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Proton delivery in NO reduction by fungal nitric-oxide reductase. Cryogenic crystallography, spectroscopy, and kinetics of ferric-NO complexes of wild-type and mutant enzymes. J.Biol.Chem., 275, 2000
1CPT	CRYSTAL STRUCTURE AND REFINEMENT OF CYTOCHROME P450-TERP AT 2.3 ANGSTROMS RESOLUTION 分子名称: CYTOCHROME P450-TERP, PROTOPORPHYRIN IX CONTAINING FE 著者 Hasemann, C.A, Ravichandran, K.G, Peterson, J.A, Deisenhofer, J. 登録日 1993-11-23 公開日 1994-01-31 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure and refinement of cytochrome P450terp at 2.3 A resolution. J.Mol.Biol., 236, 1994
8TAW	The crystal structure of T252E CYP199A4 bound to 4-(pyridin-2-yl)benzoic acid 分子名称: 4-(pyridin-2-yl)benzoic acid, CHLORIDE ION, Cytochrome P450, ... 著者 Podgorski, M.N, Bell, S.G. 登録日 2023-06-28 公開日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 Characterisation of the heme aqua-ligand coordination environment in an engineered peroxygenase cytochrome P450 variant. J.Inorg.Biochem., 249, 2023
8TAY	The crystal structure of T252E CYP199A4 bound to 4-(thiophen-3-yl)benzoic acid 分子名称: 4-(thiophen-3-yl)benzoic acid, CHLORIDE ION, Cytochrome P450, ... 著者 Podgorski, M.N, Bell, S.G. 登録日 2023-06-28 公開日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.021 Å) 主引用文献 Characterisation of the heme aqua-ligand coordination environment in an engineered peroxygenase cytochrome P450 variant. J.Inorg.Biochem., 249, 2023
8TNK	The crystal structure of the T252E mutant of CYP199A4 bound to 4-benzylbenzoic acid 分子名称: 4-benzylbenzoic acid, CHLORIDE ION, Cytochrome P450, ... 著者 Podgorski, M.N, Bell, S.G. 登録日 2023-08-02 公開日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 Characterisation of the heme aqua-ligand coordination environment in an engineered peroxygenase cytochrome P450 variant. J.Inorg.Biochem., 249, 2023
2NNI	CYP2C8dH complexed with montelukast 分子名称: Cytochrome P450 2C8, MONTELUKAST, PALMITIC ACID, ... 著者 Schoch, G.A, Yano, J.K, Stout, C.D, Johnson, E.F. 登録日 2006-10-24 公開日 2007-10-23 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Determinants of cytochrome P450 2C8 substrate binding: structures of complexes with montelukast, troglitazone, felodipine, and 9-cis-retinoic acid. J.Biol.Chem., 283, 2008
2NNH	CYP2C8dH complexed with 2 molecules of 9-cis retinoic acid 分子名称: (9cis)-retinoic acid, Cytochrome P450 2C8, PALMITIC ACID, ... 著者 Schoch, G.A, Yano, J.K, Stout, C.D, Johnson, E.F. 登録日 2006-10-24 公開日 2007-10-23 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Determinants of cytochrome P450 2C8 substrate binding: structures of complexes with montelukast, troglitazone, felodipine, and 9-cis-retinoic acid. J.Biol.Chem., 283, 2008

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