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2EFA	Neutron crystal structure of cubic insulin at pD6.6 Descriptor: Insulin Authors: Ishikawa, T, Tanaka, I, Niimura, N. Deposit date: 2007-02-22 Release date: 2008-01-22 Last modified: 2023-10-25 Method: NEUTRON DIFFRACTION (2.7 Å) Cite: A neutron crystallographic analysis of a cubic porcine insulin at pD 6.6 Chem.Phys., 345, 2008
5UDP	High resolution x-ray crystal structure of synthetic insulin lispro Descriptor: CHLORIDE ION, Insulin Lispro A chain, Insulin Lispro B chain, ... Authors: Mandal, K, Dhayalan, B, Kent, S.B.H. Deposit date: 2016-12-28 Release date: 2017-01-11 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.348 Å) Cite: Scope and Limitations of Fmoc Chemistry SPPS-Based Approaches to the Total Synthesis of Insulin Lispro via Ester Insulin. Chemistry, 23, 2017
2VK0	Crystal structure form ultalente insulin microcrystals Descriptor: 4-HYDROXY-BENZOIC ACID METHYL ESTER, INSULIN A CHAIN, INSULIN B CHAIN, ... Authors: Wagner, A, Diez, J, Schulze-Briese, C, Schluckebier, G. Deposit date: 2007-12-14 Release date: 2008-09-16 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Crystal Structure of Ultralente--A Microcrystalline Insulin Suspension. Proteins, 74, 2009
2VJZ	Crystal structure form ultalente insulin microcrystals Descriptor: CHLORIDE ION, INSULIN A CHAIN, INSULIN B CHAIN, ... Authors: Wagner, A, Diez, J, Schulze-Briese, C, Schluckebier, G. Deposit date: 2007-12-14 Release date: 2008-09-16 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Crystal Structure of Ultralente-A Microcrystalline Insulin Suspension. Proteins, 74, 2009
5USP	Insulin with proline analog Pip at position B28 in the T2 state Descriptor: Insulin Chain A, Insulin Chain B, SODIUM ION Authors: Lieblich, S.A, Fang, K.Y, Tirrell, D.A. Deposit date: 2017-02-13 Release date: 2018-02-21 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.174 Å) Cite: Insulin with proline analog Pip at position B28 in the T2 state To Be Published
5USS	Insulin with proline analog PiP at position B28 in the R6 state Descriptor: CHLORIDE ION, Insulin Chain A, Insulin Chain B, ... Authors: Lieblich, S.A, Fang, K.Y, Tirrell, D.A. Deposit date: 2017-02-13 Release date: 2018-02-21 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.061 Å) Cite: Insulin with proline analog PiP at position B28 in the R6 state To Be Published
5UU2	Insulin with proline analog ThioP at position B28 in the T2 state Descriptor: Insulin Chain A, Insulin Chain B Authors: Lieblich, S.A, Fang, K.Y, Tirrell, D.A. Deposit date: 2017-02-15 Release date: 2018-02-21 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.223 Å) Cite: Insulin with proline analog ThioP at position B28 in the T2 state To Be Published
5UU4	Insulin with proline analog ThioP at position B28 in the R6 state Descriptor: CHLORIDE ION, Insulin A Chain, Insulin B Chain, ... Authors: Lieblich, S.A, Fang, K.Y, Tirrell, D.A. Deposit date: 2017-02-16 Release date: 2018-02-21 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.973 Å) Cite: Insulin with proline analog ThioP at position B28 in the R6 state To Be Published
5USV	Insulin with proline analog AzeP at position B28 in the T2 state Descriptor: Insulin Chain A, Insulin Chain B, SODIUM ION Authors: Lieblich, S.A, Fang, K.Y, Tirrell, D.A. Deposit date: 2017-02-14 Release date: 2018-02-21 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.3 Å) Cite: Insulin with proline analog AzeP at position B28 in the T2 state To Be Published
5UOZ	Insulin with proline analog FyP at position B28 in the T2 state Descriptor: Insulin Chain A, Insulin Chain B Authors: Lieblich, S.A, Fang, K.Y, Tirrell, D.A. Deposit date: 2017-02-01 Release date: 2018-02-07 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.17463875 Å) Cite: Insulin with proline analog FyP at position B28 in the T2 state To Be Published
5URU	Insulin with proline analog DhP at position B28 in the R6 state Descriptor: CHLORIDE ION, Insulin Chain A, Insulin Chain B, ... Authors: Lieblich, S.A, Fang, K.Y, Tirrell, D.A. Deposit date: 2017-02-13 Release date: 2018-02-21 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.41 Å) Cite: Insulin with proline analog DhP at position B28 in the R6 state To Be Published
5UQA	Insulin with proline analog FzP at position B28 in the R6 state Descriptor: ACETONE, CHLORIDE ION, GLYCEROL, ... Authors: Lieblich, S.A, Fang, K.Y, Tirrell, D.A. Deposit date: 2017-02-07 Release date: 2018-02-21 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.31000245 Å) Cite: Insulin with proline analog FzP at position B28 in the R6 state To Be Published
2W44	Structure DeltaA1-A4 insulin Descriptor: CHLORIDE ION, INSULIN, RESORCINOL, ... Authors: Thorsoee, K.S, Schlein, M, Brandt, J, Schluckebier, G, Naver, H. Deposit date: 2008-11-21 Release date: 2009-12-22 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2 Å) Cite: Kinetic Evidence for the Sequential Association of Insulin Binding Sites 1 and 2 to the Insulin Receptor and the Influence of Receptor Isoform. Biochemistry, 49, 2010
5UU3	Insulin with proline analog DfP at position B28 in the R6 state Descriptor: CHLORIDE ION, Insulin, chain A, ... Authors: Lieblich, S.A, Fang, K.Y, Tirrell, D.A. Deposit date: 2017-02-16 Release date: 2018-02-21 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Insulin with proline analog DfP at position B28 in the R6 state To Be Published
5URT	Insulin with proline analog DhP at position B28 in the T2 state Descriptor: Insulin Chain A, Insulin Chain B, SODIUM ION Authors: Lieblich, S.A, Fang, K.Y, Tirrell, D.A. Deposit date: 2017-02-12 Release date: 2018-02-14 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.18 Å) Cite: Insulin with proline analog DhP at position B28 in the T2 state To Be Published
2G4M	Insulin collected at 2.0 A wavelength Descriptor: Insulin A chain, Insulin B chain Authors: Mueller-Dieckmann, C, Weiss, M.S. Deposit date: 2006-02-22 Release date: 2007-02-20 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (1.8 Å) Cite: On the routine use of soft X-rays in macromolecular crystallography. Part IV. Efficient determination of anomalous substructures in biomacromolecules using longer X-ray wavelengths. Acta Crystallogr.,Sect.D, 63, 2007
2WS0	Semi-synthetic analogue of human insulin NMeAlaB26-insulin at pH 7.5 Descriptor: INSULIN A CHAIN, INSULIN B CHAIN Authors: Brzozowski, A.M, Jiracek, J, Zakova, L, Antolikova, E, Watson, C.J, Turkenburg, J.P, Dodson, G.G. Deposit date: 2009-09-03 Release date: 2010-02-09 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Implications for the Active Form of Human Insulin Based on the Structural Convergence of Highly Active Hormone Analogues. Proc.Natl.Acad.Sci.USA, 107, 2010
2WS1	Semi-synthetic analogue of human insulin NMeTyrB26-insulin in monomer form Descriptor: ACETATE ION, INSULIN A CHAIN, INSULIN B CHAIN Authors: Brzozowski, A.M, Jiracek, J, Zakova, L, Antolikova, E, Watson, C.J, Turkenburg, J.P, Dodson, G.G. Deposit date: 2009-09-03 Release date: 2010-02-09 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Implications for the Active Form of Human Insulin Based on the Structural Convergence of Highly Active Hormone Analogues. Proc.Natl.Acad.Sci.USA, 107, 2010
2GF1	SOLUTION STRUCTURE OF HUMAN INSULIN-LIKE GROWTH FACTOR 1: A NUCLEAR MAGNETIC RESONANCE AND RESTRAINED MOLECULAR DYNAMICS STUDY Descriptor: INSULIN-LIKE GROWTH FACTOR I Authors: Cooke, R.M, Harvey, T.S, Campbell, I.D. Deposit date: 1991-01-23 Release date: 1993-04-15 Last modified: 2022-03-09 Method: SOLUTION NMR Cite: Solution structure of human insulin-like growth factor 1: a nuclear magnetic resonance and restrained molecular dynamics study. Biochemistry, 30, 1991
2WRX	Semi-synthetic analogue of human insulin NMeAlaB26-insulin at pH 3.0 Descriptor: INSULIN A CHAIN, INSULIN B CHAIN, SODIUM ION Authors: Brzozowski, A.M, Jiracek, J, Zakova, L, Antolikova, E, Watson, C.J, Turkenburg, J.P, Dodson, G.G. Deposit date: 2009-09-02 Release date: 2010-02-09 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Implications for the Active Form of Human Insulin Based on the Structural Convergence of Highly Active Hormone Analogues. Proc.Natl.Acad.Sci.USA, 107, 2010
2WS6	Semi-synthetic analogue of human insulin NMeTyrB26-insulin in hexamer form Descriptor: CHLORIDE ION, GLYCEROL, INSULIN A CHAIN, ... Authors: Brzozowski, A.M, Jiracek, J, Zakova, L, Antolikova, E, Watson, C.J, Turkenburg, J.P, Dodson, G.G. Deposit date: 2009-09-03 Release date: 2010-02-09 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Implications for the Active Form of Human Insulin Based on the Structural Convergence of Highly Active Hormone Analogues. Proc.Natl.Acad.Sci.USA, 107, 2010
5VIZ	X-Ray structure of Insulin Glargine Descriptor: Insulin, chain alpha, chain beta Authors: Reyes-Grajeda, J.P, Romero, A. Deposit date: 2017-04-17 Release date: 2017-10-18 Method: X-RAY DIFFRACTION (1.7 Å) Cite: X-Ray structure of Insulin Glargine To Be Published
2H67	NMR structure of human insulin mutant HIS-B5-ALA, HIS-B10-ASP PRO-B28-LYS, LYS-B29-PRO, 20 structures Descriptor: Insulin A chain, Insulin B chain Authors: Hua, Q.X, Liu, M, Hu, S.Q, Jia, W, Arvan, P, Weiss, M.A. Deposit date: 2006-05-30 Release date: 2006-07-18 Last modified: 2021-10-20 Method: SOLUTION NMR Cite: A Conserved Histidine in Insulin Is Required for the Foldability of Human Proinsulin: Structure and function of an Alab5 analog. J.Biol.Chem., 281, 2006
5WDM	An ultra-stable single-chain insulin analog resists thermal inactivation and exhibits biological signaling duration equivalent to the native protein Descriptor: Single-chain insulin analog Authors: Yee, V.C, Aldabbagh, K, Peng, Y. Deposit date: 2017-07-05 Release date: 2017-11-15 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.803 Å) Cite: An ultra-stable single-chain insulin analog resists thermal inactivation and exhibits biological signaling duration equivalent to the native protein. J. Biol. Chem., 293, 2018
2HIU	NMR STRUCTURE OF HUMAN INSULIN IN 20% ACETIC ACID, ZINC-FREE, 10 STRUCTURES Descriptor: INSULIN Authors: Hua, Q.X, Gozani, S.N, Chance, R.E, Hoffmann, J.A, Frank, B.H, Weiss, M.A. Deposit date: 1996-10-08 Release date: 1997-04-01 Last modified: 2017-11-29 Method: SOLUTION NMR Cite: Structure of a protein in a kinetic trap. Nat.Struct.Biol., 2, 1995

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