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8ZGS
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BU of 8zgs by Molmil
Structure of the ige-fc bound to its high affinity receptor fc(epsilon)ri state2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, ...
Authors:Du, S, Deng, M.J, Xiao, J.Y.
Deposit date:2024-05-09
Release date:2024-07-10
Last modified:2024-10-09
Method:ELECTRON MICROSCOPY (3.04 Å)
Cite:Structural insights into the high-affinity IgE receptor Fc epsilon RI complex.
Nature, 633, 2024
8ZGT
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BU of 8zgt by Molmil
Structure of the ige-fc bound to its high affinity receptor fc(epsilon)ri state3
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, ...
Authors:Du, S, Deng, M.J, Xiao, J.Y.
Deposit date:2024-05-09
Release date:2024-07-10
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (2.96 Å)
Cite:Structural insights into the high-affinity IgE receptor Fc epsilon RI complex.
Nature, 633, 2024
8Z7N
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BU of 8z7n by Molmil
Structure of HIV-1 CH119 SOSIP.664 trimer in complex with CD4 molecules
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, T-cell surface glycoprotein CD4
Authors:Li, D, Wang, T.
Deposit date:2024-04-20
Release date:2024-09-18
Method:ELECTRON MICROSCOPY (3.58 Å)
Cite:Intermediate open state of CD4-bound HIV-1 env heterotrimers in asia CRFs
Biochem Biophys Res Commun, 725, 2024
8Y81
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BU of 8y81 by Molmil
Structure of the ige-fc bound to its high affinity receptor fc(epsilon)ri
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, ...
Authors:Du, S, Deng, M.J, Xiao, J.Y.
Deposit date:2024-02-05
Release date:2024-07-10
Last modified:2024-10-09
Method:ELECTRON MICROSCOPY (2.89 Å)
Cite:Structural insights into the high-affinity IgE receptor Fc epsilon RI complex.
Nature, 633, 2024
8QY5
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BU of 8qy5 by Molmil
Structure of interleukin 6.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-6, ...
Authors:Gardner, S, Bubeck, D, Jin, Y.
Deposit date:2023-10-25
Release date:2024-02-21
Last modified:2024-10-09
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural insights into IL-11-mediated signalling and human IL6ST variant-associated immunodeficiency.
Nat Commun, 15, 2024
8QY6
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BU of 8qy6 by Molmil
Structure of interleukin 6 (gp130 P496L mutant).
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-6, ...
Authors:Gardner, S, Bubeck, D, Jin, Y.
Deposit date:2023-10-25
Release date:2024-02-21
Last modified:2024-09-04
Method:ELECTRON MICROSCOPY (3.16 Å)
Cite:Structural insights into IL-11-mediated signalling and human IL6ST variant-associated immunodeficiency.
Nat Commun, 15, 2024
8W90
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BU of 8w90 by Molmil
crystal structure of CD4-D1D2 with Nb457
Descriptor: NB457, T-cell surface glycoprotein CD4
Authors:Wang, X.Y, Wang, Y.X.
Deposit date:2023-09-04
Release date:2024-09-04
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Structure of CD4-D1D2 domain and nanobody Nb457 at 1.78 Angstroms resolution
To Be Published
8TUI
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BU of 8tui by Molmil
Crystal structure of Fab-Lirilumab bound to KIR2DL3
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Killer cell immunoglobulin-like receptor 2DL3, Lirilumab Fab Heavy Chain, ...
Authors:Lorig-Roach, N, DuBois, R.M.
Deposit date:2023-08-16
Release date:2023-12-06
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structural basis for the activity and specificity of the immune checkpoint inhibitor lirilumab.
Sci Rep, 14, 2024
8K7T
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BU of 8k7t by Molmil
Mouse Fc epsilon RI in complex with mIgE Fc
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, High affinity immunoglobulin epsilon receptor subunit alpha, High affinity immunoglobulin epsilon receptor subunit beta, ...
Authors:Zhang, Z, Yui, M, Ohto, U, Shimizu, T.
Deposit date:2023-07-27
Release date:2024-07-17
Method:ELECTRON MICROSCOPY (3.71 Å)
Cite:Mouse Fc epsilon RI in complex withMouse Fc epsilon RI in complex with mIgE Fc mIgE Fc
To Be Published
8OVQ
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BU of 8ovq by Molmil
Crystal structure of Geodia cydonium sponge adhesion molecule long form (SAML).
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Cell recognition molecule, ...
Authors:Lopez-Sagaseta, J, Urdiciain, A.
Deposit date:2023-04-26
Release date:2024-06-26
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:Crystal structure of Geodia cydonium sponge adhesion molecule long form (SAML).
To Be Published
8SM2
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BU of 8sm2 by Molmil
Crystal Structure of the macaque FcalphaRI bound to macaque IgA Fc.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Ig-like domain-containing protein, Immunoglobulin subtype domain-containing protein, ...
Authors:Tolbert, W.D, Pazgier, M.
Deposit date:2023-04-25
Release date:2024-05-08
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Crystal Structure of the macaque FcalphaRI bound to macaque IgA Fc.
To Be Published
8J6F
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BU of 8j6f by Molmil
Cryo-EM structure of the Tocilizumab Fab/IL-6R complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of Tocilizumab Fab, IL6R-D2 peptide, ...
Authors:She, J, Chen, L.
Deposit date:2023-04-25
Release date:2024-03-27
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Cryo-EM structures of tocilizumab and sarilumab Fabs in complex with IL-6R
To Be Published
8SKU
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BU of 8sku by Molmil
Structure of human SIgA1 in complex with human CD89 (FcaR1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoglobulin J chain, ...
Authors:Liu, Q, Stadtmueller, B.M.
Deposit date:2023-04-20
Release date:2023-10-25
Last modified:2023-11-08
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:SIgA structures bound to Streptococcus pyogenes M4 and human CD89 provide insights into host-pathogen interactions.
Nat Commun, 14, 2023
8SKV
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BU of 8skv by Molmil
Structure of human SIgA1 in complex with Streptococcus pyogenes protein M4 (Arp4)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, IgA receptor, ...
Authors:Liu, Q, Stadtmueller, B.M.
Deposit date:2023-04-20
Release date:2023-10-25
Last modified:2023-11-08
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:SIgA structures bound to Streptococcus pyogenes M4 and human CD89 provide insights into host-pathogen interactions.
Nat Commun, 14, 2023
8IOW
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BU of 8iow by Molmil
Cryo-EM structure of the sarilumab Fab/IL-6R complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of Sarilumab Fab, Interleukin-6 receptor subunit alpha, ...
Authors:She, J, Chen, L, Wang, M.X.
Deposit date:2023-03-13
Release date:2024-03-20
Last modified:2024-10-09
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural insights into IL-6 signaling inhibition by therapeutic antibodies.
Cell Rep, 43, 2024
8FYI
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BU of 8fyi by Molmil
Structure of HIV-1 BG505 SOSIP-HT1 in complex with one CD4 molecule
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(6-8)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Fan, C, Dam, K.A, Bjorkman, P.J.
Deposit date:2023-01-26
Release date:2023-10-18
Last modified:2023-12-13
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Intermediate conformations of CD4-bound HIV-1 Env heterotrimers.
Nature, 623, 2023
8FYJ
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BU of 8fyj by Molmil
Structure of HIV-1 BG505 SOSIP-HT2 in complex with two CD4 molecules (class I)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ...
Authors:Fan, C, Dam, K.A, Bjorkman, P.J.
Deposit date:2023-01-26
Release date:2023-10-18
Last modified:2023-12-13
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Intermediate conformations of CD4-bound HIV-1 Env heterotrimers.
Nature, 623, 2023
8EMA
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BU of 8ema by Molmil
mouse full length B cell receptor
Descriptor: Anti-human Langerin 2G3 lambda chain, B-cell antigen receptor complex-associated protein alpha chain, B-cell antigen receptor complex-associated protein beta chain, ...
Authors:Ying, D, Xiong, P, Michael, R.
Deposit date:2022-09-27
Release date:2022-11-16
Last modified:2022-12-07
Method:ELECTRON MICROSCOPY (8.2 Å)
Cite:Structural principles of B cell antigen receptor assembly.
Nature, 612, 2022
8GRX
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BU of 8grx by Molmil
APOE4 receptor in complex with APOE4 NTD
Descriptor: Apolipoprotein E, Leukocyte immunoglobulin-like receptor subfamily A member 6
Authors:Zhou, J, Wang, Y, Huang, G, Shi, Y.
Deposit date:2022-09-02
Release date:2023-07-05
Method:ELECTRON MICROSCOPY (3 Å)
Cite:LilrB3 is a putative cell surface receptor of APOE4.
Cell Res., 33, 2023
8E4C
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BU of 8e4c by Molmil
IgM BCR fab truncated form
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, B-cell antigen receptor complex-associated protein alpha chain,Yellow fluorescent protein, B-cell antigen receptor complex-associated protein beta chain, ...
Authors:Dong, Y, Pi, X, Wu, H, Reth, M.
Deposit date:2022-08-18
Release date:2022-11-16
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structural principles of B cell antigen receptor assembly.
Nature, 612, 2022
8DJ7
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BU of 8dj7 by Molmil
The complex structure between human IgG1 Fc and its high affinity receptor FcgRI H174R variant
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, High affinity immunoglobulin gamma Fc receptor I, Ig gamma-1 Fc chain, ...
Authors:Lu, J, Sun, P.D.
Deposit date:2022-06-30
Release date:2023-05-10
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Fc gamma RI FG-loop functions as a pH sensitive switch for IgG binding and release.
Front Immunol, 14, 2023
8DIN
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BU of 8din by Molmil
The complex structure between human IgG1 Fc and its high affinity receptor FcgRI H174R variant
Descriptor: High affinity immunoglobulin gamma Fc receptor I, Ig gamma-1 Fc chain, MAGNESIUM ION, ...
Authors:Lu, J, Sun, P.D.
Deposit date:2022-06-29
Release date:2023-05-10
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Fc gamma RI FG-loop functions as a pH sensitive switch for IgG binding and release.
Front Immunol, 14, 2023
8DIR
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BU of 8dir by Molmil
The complex structure between human IgG1 Fc and its high affinity receptor FcgRI H174R variant
Descriptor: High affinity immunoglobulin gamma Fc receptor I, Ig gamma-1 Fc chain, SODIUM ION, ...
Authors:Lu, J, Sun, P.D.
Deposit date:2022-06-29
Release date:2023-05-10
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Fc gamma RI FG-loop functions as a pH sensitive switch for IgG binding and release.
Front Immunol, 14, 2023
8DFM
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BU of 8dfm by Molmil
Ectodomain of full-length wild-type KIT-SCF dimers
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Isoform 2 of Mast/stem cell growth factor receptor Kit, ...
Authors:Krimmer, S.G, Bertoletti, N, Mi, W, Schlessinger, J.
Deposit date:2022-06-22
Release date:2023-03-29
Last modified:2023-04-05
Method:ELECTRON MICROSCOPY (3.45 Å)
Cite:Cryo-EM analyses of KIT and oncogenic mutants reveal structural oncogenic plasticity and a target for therapeutic intervention.
Proc.Natl.Acad.Sci.USA, 120, 2023
8DFQ
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BU of 8dfq by Molmil
Ectodomain of full-length KIT(T417I,delta418-419)-SCF dimers
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Isoform 2 of Mast/stem cell growth factor receptor Kit, ...
Authors:Krimmer, S.G, Bertoletti, N, Mi, W, Schlessinger, J.
Deposit date:2022-06-22
Release date:2023-03-29
Last modified:2023-04-05
Method:ELECTRON MICROSCOPY (3.96 Å)
Cite:Cryo-EM analyses of KIT and oncogenic mutants reveal structural oncogenic plasticity and a target for therapeutic intervention.
Proc.Natl.Acad.Sci.USA, 120, 2023

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PDB entries from 2024-10-16

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