8IOW

Cryo-EM structure of the sarilumab Fab/IL-6R complex

This is a non-PDB format compatible entry.

Summary for 8IOW

• Entry DOI: 10.2210/pdb8iow/pdb
• EMDB information: 35627
• Descriptor: Interleukin-6 receptor subunit alpha, Light chain of Sarilumab Fab, Heavy chain of Sarilumab Fab, ... (4 entities in total)
• Functional Keywords: antibody, il-6r, structural protein, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 128088.74

Authors

She, J.,Chen, L.,Wang, M.X. (deposition date: 2023-03-13, release date: 2024-03-20)

• Primary citation: She, J.,Wang, M.X.,Chen, L.; Cryo-EM structure of the sarilumab Fab/IL-6R complex; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.2 Å)