8J6F

Cryo-EM structure of the Tocilizumab Fab/IL-6R complex

Summary for 8J6F

Entry DOI	10.2210/pdb8j6f/pdb
EMDB information	36003
Descriptor	Heavy chain of Tocilizumab Fab, Light chain of Tocilizumab Fab, Interleukin-6 receptor subunit alpha, ... (5 entities in total)
Functional Keywords	antibody, il-6r, structural protein, immune system
Biological source	Homo sapiens (human) More
Total number of polymer chains	4
Total formula weight	89305.16
Authors	She, J.,Chen, L. (deposition date: 2023-04-25, release date: 2024-03-27)
Primary citation	She, J.,Wang, M.X. Cryo-EM structures of tocilizumab and sarilumab Fabs in complex with IL-6R To Be Published,
Experimental method	ELECTRON MICROSCOPY (3.3 Å)

Structure validation