5Y32
 
 | | Crystal structure of PTP delta Ig1-Ig2 in complex with IL1RAPL1 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Yamagata, A, Fukai, S. | | Deposit date: | 2017-07-27 | | Release date: | 2017-08-16 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.701 Å) | | Cite: | Mechanisms of splicing-dependent trans-synaptic adhesion by PTP delta-IL1RAPL1/IL-1RAcP for synaptic differentiation.
Nat Commun, 6, 2015
|
|
7DUU
 | | Crystal structure of HLA molecule with an KIR receptor | | Descriptor: | Beta-2-microglobulin, Killer cell immunoglobulin-like receptor 2DS2, LEU-ASN-PRO-SER-VAL-ALA-ALA-THR-LEU, ... | | Authors: | Yang, Y, Yin, L. | | Deposit date: | 2021-01-11 | | Release date: | 2022-02-02 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.51 Å) | | Cite: | Activating receptor KIR2DS2 bound to HLA-C1 reveals the novel recognition features of activating receptor.
Immunology, 165, 2022
|
|
4DKD
 | | Crystal Structure of Human Interleukin-34 Bound to Human CSF-1R | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-34, ... | | Authors: | Ma, X, Bazan, J.F, Starovasnik, M.A. | | Deposit date: | 2012-02-03 | | Release date: | 2012-04-11 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structural Basis for the Dual Recognition of Helical Cytokines IL-34 and CSF-1 by CSF-1R.
Structure, 20, 2012
|
|
3EJJ
 | | Structure of M-CSF bound to the first three domains of FMS | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Colony stimulating factor-1, Macrophage colony-stimulating factor 1 receptor | | Authors: | Chen, X, Liu, H, Focia, P.J, Shim, A, He, X. | | Deposit date: | 2008-09-18 | | Release date: | 2008-12-09 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structure of macrophage colony stimulating factor bound to FMS: diverse signaling assemblies of class III receptor tyrosine kinases.
Proc.Natl.Acad.Sci.USA, 105, 2008
|
|
8I9M
 | | The RAGE and HMGB1 complex | | Descriptor: | Advanced glycosylation end product-specific receptor, High mobility group protein B1 | | Authors: | Han, C.W, Kim, H.J. | | Deposit date: | 2023-02-07 | | Release date: | 2024-02-14 | | Method: | ELECTRON MICROSCOPY (5.19 Å) | | Cite: | The RAGE and HMGB1 complex
To Be Published
|
|
8J6F
 | | Cryo-EM structure of the Tocilizumab Fab/IL-6R complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of Tocilizumab Fab, IL6R-D2 peptide, ... | | Authors: | She, J, Chen, L. | | Deposit date: | 2023-04-25 | | Release date: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Cryo-EM structures of tocilizumab and sarilumab Fabs in complex with IL-6R
To Be Published
|
|
4EXP
 | | Structure of mouse Interleukin-34 in complex with mouse FMS | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-34, Macrophage colony-stimulating factor 1 receptor | | Authors: | Liu, H, Leo, C, Chen, X, Wong, B.R, Williams, L.T, Lin, H, He, X. | | Deposit date: | 2012-04-30 | | Release date: | 2012-05-30 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | The mechanism of shared but distinct CSF-1R signaling by the non-homologous cytokines IL-34 and CSF-1.
Biochim.Biophys.Acta, 1824, 2012
|
|
8IOW
 | |
6AEE
 | | Crystal structure of the four Ig-like domains of LILRB1 complexed with HLA-G | | Descriptor: | 9 Mer Peptide (RL9) From Histone H2A.x, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | | Authors: | Wang, Q, Song, H, Qi, J, Gao, G.F. | | Deposit date: | 2018-08-04 | | Release date: | 2019-07-31 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (3.303 Å) | | Cite: | Structures of the four Ig-like domain LILRB2 and the four-domain LILRB1 and HLA-G1 complex.
Cell. Mol. Immunol., 2019
|
|
6AED
 | |
5IHB
 | | Structure of the immune receptor CD33 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Myeloid cell surface antigen CD33 | | Authors: | Dodd, R.B. | | Deposit date: | 2016-02-29 | | Release date: | 2017-03-29 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.24 Å) | | Cite: | Structure of ligand bound CD33 receptor associated with Alzheimer's disease
To Be Published
|
|
5J06
 | | Structure of the immune receptor CD33 in complex with 3'-sialyllactose | | Descriptor: | 2-(2-METHOXYETHOXY)ETHANOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Myeloid cell surface antigen CD33, ... | | Authors: | Dodd, R.B. | | Deposit date: | 2016-03-27 | | Release date: | 2017-04-05 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.66 Å) | | Cite: | STRUCTURE OF LIGAND BOUND CD33 RECEPTOR ASSOCIATED WITH ALZHEIMER'S DISEASE
To Be Published
|
|
5J0B
 | | Structure of the immune receptor CD33 in complex with 6'-sialyllactose | | Descriptor: | 2-(2-METHOXYETHOXY)ETHANOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Myeloid cell surface antigen CD33, ... | | Authors: | Dodd, R.B. | | Deposit date: | 2016-03-28 | | Release date: | 2017-04-05 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.48 Å) | | Cite: | STRUCTURE OF LIGAND BOUND CD33 RECEPTOR ASSOCIATED WITH ALZHEIMER'S DISEASE
To Be Published
|
|
7K80
 | | KIR3DL1*001 in complex with HLA-A*24:02 presenting the RYPLTFGW peptide | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ARG-TYR-PRO-LEU-THR-PHE-GLY-TRP, ... | | Authors: | MacLachlan, B.J, Rossjohn, J, Vivian, J.P. | | Deposit date: | 2020-09-24 | | Release date: | 2020-12-09 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | The Role of the HLA Class I alpha 2 Helix in Determining Ligand Hierarchy for the Killer Cell Ig-like Receptor 3DL1.
J Immunol., 206, 2021
|
|
7K81
 | | KIR3DL1*005 in complex with HLA-A*24:02 presenting the RYPLTFGW peptide | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ARG-TYR-PRO-LEU-THR-PHE-GLY-TRP, Beta-2-microglobulin, ... | | Authors: | MacLachlan, B.J, Rossjohn, J, Vivian, J.P. | | Deposit date: | 2020-09-24 | | Release date: | 2020-12-09 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | The Role of the HLA Class I alpha 2 Helix in Determining Ligand Hierarchy for the Killer Cell Ig-like Receptor 3DL1.
J Immunol., 206, 2021
|
|
7KFK
 | |
7UVL
 | | IgA1 Protease with IgA1 substrate | | Descriptor: | Immunoglobulin alpha-1 heavy chain, Immunoglobulin alpha-1 heavy constant, Immunoglobulin alpha-1 light chain, ... | | Authors: | Eisenmesser, Z.E, Zheng, H. | | Deposit date: | 2022-05-02 | | Release date: | 2022-11-23 | | Method: | ELECTRON MICROSCOPY (3.56 Å) | | Cite: | A substrate-induced gating mechanism is conserved among Gram-positive IgA1 metalloproteases.
Commun Biol, 5, 2022
|
|
1WIP
 | |
1GC1
 | | HIV-1 GP120 CORE COMPLEXED WITH CD4 AND A NEUTRALIZING HUMAN ANTIBODY | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ANTIBODY 17B, CD4, ... | | Authors: | Kwong, P.D, Wyatt, R, Robinson, J, Sweet, R.W, Sodroski, J, Hendrickson, W.A. | | Deposit date: | 1998-06-15 | | Release date: | 1998-07-08 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody.
Nature, 393, 1998
|
|
1WIO
 | |
1G9M
 | | HIV-1 HXBC2 GP120 ENVELOPE GLYCOPROTEIN COMPLEXED WITH CD4 AND INDUCED NEUTRALIZING ANTIBODY 17B | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ANTIBODY 17B, HEAVY CHAIN, ... | | Authors: | Kwong, P.D, Wyatt, R, Majeed, S, Robinson, J, Sweet, R.W, Sodroski, J, Hendrickson, W.A. | | Deposit date: | 2000-11-24 | | Release date: | 2000-12-27 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structures of HIV-1 gp120 envelope glycoproteins from laboratory-adapted and primary isolates.
Structure Fold.Des., 8, 2000
|
|
1WIQ
 | |
1G9N
 | | HIV-1 YU2 GP120 ENVELOPE GLYCOPROTEIN COMPLEXED WITH CD4 AND INDUCED NEUTRALIZING ANTIBODY 17B | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ANTIBODY 17B, HEAVY CHAIN, ... | | Authors: | Kwong, P.D, Wyatt, R, Majeed, S, Robinson, J, Sweet, R.W, Sodroski, J, Hendrickson, W.A. | | Deposit date: | 2000-11-25 | | Release date: | 2000-12-27 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Structures of HIV-1 gp120 envelope glycoproteins from laboratory-adapted and primary isolates.
Structure Fold.Des., 8, 2000
|
|
8SKU
 | | Structure of human SIgA1 in complex with human CD89 (FcaR1) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoglobulin J chain, ... | | Authors: | Liu, Q, Stadtmueller, B.M. | | Deposit date: | 2023-04-20 | | Release date: | 2023-10-25 | | Last modified: | 2023-11-08 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | SIgA structures bound to Streptococcus pyogenes M4 and human CD89 provide insights into host-pathogen interactions.
Nat Commun, 14, 2023
|
|
8SKV
 | |
