PDB: 186 件ウェブページステータス検索Chemie searchBIRD

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2R5Y	Structure of Scr/Exd complex bound to a consensus Hox-Exd site 分子名称: DNA (5'-D(*DAP*DCP*DTP*DCP*DTP*DAP*DTP*DGP*DAP*DTP*DTP*DTP*DAP*DTP*DGP*DGP*DGP*DCP*DTP*DG)-3'), DNA (5'-D(*DTP*DCP*DAP*DGP*DCP*DCP*DCP*DAP*DTP*DAP*DAP*DAP*DTP*DCP*DAP*DTP*DAP*DGP*DAP*DG)-3'), Homeobox protein extradenticle, ... 著者 Aggarwal, A.K, Passner, J.M, Jain, R. 登録日 2007-09-04 公開日 2008-02-05 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Functional specificity of a Hox protein mediated by the recognition of minor groove structure Cell(Cambridge,Mass.), 131, 2007
2R5Z	Structure of Scr/Exd complex bound to a DNA sequence derived from the fkh gene 分子名称: DNA (5'-D(*DAP*DCP*DTP*DCP*DTP*DAP*DAP*DGP*DAP*DTP*DTP*DAP*DAP*DTP*DCP*DGP*DGP*DCP*DTP*DG)-3'), DNA (5'-D(*DTP*DCP*DAP*DGP*DCP*DCP*DGP*DAP*DTP*DTP*DAP*DAP*DTP*DCP*DTP*DTP*DAP*DGP*DAP*DG)-3'), Homeobox protein extradenticle, ... 著者 Aggarwal, A.K, Passner, J.M, Jain, R. 登録日 2007-09-04 公開日 2008-02-05 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Functional specificity of a Hox protein mediated by the recognition of minor groove structure Cell(Cambridge,Mass.), 131, 2007
8BX1	Oct4/Sox2 protein:DNA complex 分子名称: HOXB1_f, HOXB1_r, POU domain, ... 著者 Chojnowski, G, Wilmanns, M, Round, E. 登録日 2022-12-07 公開日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of Oct4-Soc2-HoxB1 complex To Be Published
8BX2	Oct4/Sox2 protein:DNA complex 分子名称: POU domain, class 5, transcription factor 1, ... 著者 Chojnowski, G, Wilmanns, M, Round, E. 登録日 2022-12-07 公開日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.14 Å) 主引用文献 Crystal structure of Oct4-Soc2-UTF1 complex To Be Published
8SPU	Structure of ESRRB nucleosome bound OCT4 at site c 分子名称: DNA (168-MER), Histone H2A type 2-C, Histone H2B type 2-E, ... 著者 Lian, T, Guan, R, Bai, Y. 登録日 2023-05-03 公開日 2023-06-28 最終更新日 2024-02-07 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Structural mechanism of LIN28B nucleosome targeting by OCT4. Mol.Cell, 83, 2023
8SPS	High resolution structure of ESRRB nucleosome bound OCT4 at site a and site b 分子名称: DNA (168-MER), Histone H2A type 2-C, Histone H2B type 2-E, ... 著者 Lian, T, Guan, R, Bai, Y. 登録日 2023-05-03 公開日 2023-06-28 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Structural mechanism of LIN28B nucleosome targeting by OCT4. Mol.Cell, 83, 2023
4S0H	TBX5 DB, NKX2.5 HD, ANF DNA Complex 分子名称: 5'-D(*CP*CP*AP*CP*TP*TP*CP*AP*AP*AP*GP*GP*TP*GP*TP*GP*AP*GP*A)-3', 5'-D(*TP*CP*TP*CP*AP*CP*AP*CP*CP*TP*TP*TP*GP*AP*AP*GP*TP*GP*G)-3', Homeobox protein Nkx-2.5, ... 著者 Pradhan, L. 登録日 2014-12-31 公開日 2015-12-16 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.817 Å) 主引用文献 Intermolecular Interactions of Cardiac Transcription Factors NKX2.5 and TBX5. Biochemistry, 55, 2016
5ZJQ	Structure of AbdB/Exd complex bound to a 'Red14' DNA sequence 分子名称: DNA (5'-D(*GP*CP*AP*TP*GP*AP*TP*TP*TP*AP*TP*GP*AP*C)-3'), DNA (5'-D(*GP*TP*CP*AP*TP*AP*AP*AP*TP*CP*AP*TP*GP*C)-3'), Homeobox protein abdominal-B, ... 著者 Baburajendran, N, Zeiske, T, Kaczynska, A, Mann, R, Honig, B, Shapiro, L, Palmer, A.G. 登録日 2018-03-22 公開日 2018-08-29 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.443 Å) 主引用文献 Intrinsic DNA Shape Accounts for Affinity Differences between Hox-Cofactor Binding Sites. Cell Rep, 24, 2018
1S7E	Solution structure of HNF-6 分子名称: Hepatocyte nuclear factor 6 著者 Liao, X, Sheng, W. 登録日 2004-01-29 公開日 2004-12-28 最終更新日 2022-03-02 実験手法 SOLUTION NMR 主引用文献 Structure of the hepatocyte nuclear factor 6alpha and its interaction with DNA. J.Biol.Chem., 279, 2004
2XSD	Crystal Structure of the dimeric Oct-6 (Pou3f1) POU domain bound to palindromic MORE DNA 分子名称: 1,2-ETHANEDIOL, 5'-D(*AP*TP*GP*CP*AP*TP*GP*AP*GP*GP*AP)-3', 5'-D(*CP*CP*TP*CP*AP*TP*GP*CP*AP*TP*AP)-3', ... 著者 Jauch, R, Choo, S.H, Ng, C.K.L, Kolatkar, P.R. 登録日 2010-09-28 公開日 2010-10-20 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.049 Å) 主引用文献 Crystal Structure of the Dimeric Oct6 (POU3F1) POU Domain Bound to Palindromic More DNA. Proteins, 79, 2011
4UUS	CRYSTAL STRUCTURE OF A UBX-EXD-DNA COMPLEX INCLUDING THE UBDA MOTIF 分子名称: 5'-D(*AP*CP*GP*TP*GP*AP*TP*TP*TP*AP*TP*GP*GP*CP*G)-3', 5'-D(*GP*TP*CP*GP*CP*CP*AP*TP*AP*AP*AP*TP*CP*AP*C)-3', HOMEOTIC PROTEIN EXTRADENTICLE, ... 著者 Foos, N, Mate, M.J, Ortiz-Lombardia, M. 登録日 2014-07-31 公開日 2015-02-18 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 A Flexible Extension of the Drosophila Ultrabithorax Homeodomain Defines a Novel Hox/Pbc Interaction Mode. Structure, 23, 2015
4XRS	Heterodimeric complex of transcription factors MEIS1 and DLX3 on specific DNA 分子名称: DNA (5'-D(P*AP*CP*AP*AP*TP*TP*AP*TP*CP*CP*TP*GP*TP*CP*AP*AP*C)-3'), DNA (5'-D(P*CP*AP*AP*TP*TP*AP*TP*CP*CP*TP*GP*TP*CP*AP*A)-3'), DNA (5'-D(P*GP*TP*TP*GP*AP*CP*AP*GP*GP*AP*TP*AP*AP*TP*TP*GP*TP*T)-3'), ... 著者 Jorma, A, Yin, Y, Nitta, K.R, Dave, K, Enge, M, Kivioja, T, Popov, A, Morgunova, E, Taipale, J. 登録日 2015-01-21 公開日 2015-11-04 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature, 527, 2015
1B8I	STRUCTURE OF THE HOMEOTIC UBX/EXD/DNA TERNARY COMPLEX 分子名称: DNA (5'-D(*AP*CP*GP*TP*GP*AP*TP*TP*TP*AP*TP*GP*GP*CP*G)-3'), DNA (5'-D(*GP*TP*CP*GP*CP*CP*AP*TP*AP*AP*AP*TP*CP*AP*C)-3'), PROTEIN (HOMEOBOX PROTEIN EXTRADENTICLE), ... 著者 Passner, J.M, Ryoo, H.-D, Shen, L, Mann, R.S, Aggarwal, A.K. 登録日 1999-02-01 公開日 1999-04-12 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure of a DNA-bound Ultrabithorax-Extradenticle homeodomain complex. Nature, 397, 1999
1AU7	PIT-1 MUTANT/DNA COMPLEX 分子名称: CONSENSUS DNA 25-MER, DNA (5'-D(*CP*TP*TP*CP*CP*TP*CP*AP*TP*GP*TP*AP*TP*AP*TP*AP*C P*AP*TP*GP*AP*GP* GP*A)-3'), PROTEIN PIT-1 著者 Jacobson, E.M, Li, P, Leon-Del-Rio, A, Rosenfeld, M.G, Aggarwal, A.K. 登録日 1997-09-12 公開日 1998-01-28 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure of Pit-1 POU domain bound to DNA as a dimer: unexpected arrangement and flexibility. Genes Dev., 11, 1997
1GT0	Crystal structure of a POU/HMG/DNA ternary complex 分子名称: 5'-D(*AP*TP*CP*CP*CP*AP*TP*TP*AP*GP* CP*AP*TP*CP*CP*AP*AP*AP*CP*AP*AP*AP*GP*A)-3', 5'-D(*TP*TP*CP*TP*TP*TP*GP*TP*TP*TP* GP*GP*AP* TP*GP*CP*TP*AP*AP*TP*GP*GP*GP*A)-3', OCTAMER-BINDING TRANSCRIPTION FACTOR 1, ... 著者 Remenyi, A, Wilmanns, M. 登録日 2002-01-09 公開日 2003-01-30 最終更新日 2019-07-24 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal Structure of a POU/Hmg/DNA Ternary Complex Suggests Differential Assembly of Oct4 and Sox2 on Two Enhancers Genes Dev., 17, 2003
5FLV	Crystal structure of NKX2-5 and TBX5 bound to the Nppa promoter region 分子名称: 5'-D(*AP*CP*CP*AP*CP*TP*TP*CP*AP*AP*AP*GP*GP*TP *GP*TP*GP*AP*GP*AP*AP*G)-3', 5'-D(*TP*CP*TP*TP*CP*TP*CP*AP*CP*AP*CP*CP*TP*TP *TP*GP*AP*AP*GP*TP*GP*G)-3', HOMEOBOX PROTEIN NKX-2.5, ... 著者 Stirnimann, C.U, Glatt, S, Mueller, C.W. 登録日 2015-10-28 公開日 2016-02-10 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.005 Å) 主引用文献 Complex Interdependence Regulates Heterotypic Transcription Factor Distribution and Coordinates Cardiogenesis. Cell(Cambridge,Mass.), 164, 2016
5EGO	HOXB13-MEIS1 heterodimer bound to methylated DNA 分子名称: DNA (5'-D(*CP*CP*TP*(5CM)P*GP*TP*AP*AP*AP*AP*CP*TP*GP*TP*CP*AP*AP*C)-3'), DNA (5'-D(P*GP*TP*TP*GP*AP*CP*AP*GP*TP*TP*TP*TP*AP*(5CM)P*GP*AP*GP*G)-3'), Homeobox protein Hox-B13, ... 著者 Morgunova, E, Yin, Y, Jolma, A, Popov, A, Taipale, J. 登録日 2015-10-27 公開日 2016-11-09 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.54 Å) 主引用文献 Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science, 356, 2017
5EG0	HOXB13-MEIS1 heterodimer bound to DNA 分子名称: DNA (5'-D(*CP*CP*TP*CP*GP*TP*AP*AP*AP*AP*CP*TP*GP*TP*CP*AP*AP*C)-3'), DNA (5'-D(P*GP*TP*TP*GP*AP*CP*AP*GP*TP*TP*TP*TP*AP*CP*GP*AP*GP*G)-3'), Homeobox protein Hox-B13, ... 著者 Morgunova, E, Yin, Y, Jolma, A, Popov, A, Taipale, J. 登録日 2015-10-26 公開日 2016-11-09 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.101 Å) 主引用文献 Molecular basis of recognition of two distinct DNA sequences by a single transcription factor To Be Published
5WC9	Human Pit-1 and 4xCATT DNA complex 分子名称: DNA (5'-D(*CP*CP*AP*TP*TP*CP*AP*TP*TP*CP*AP*TP*TP*CP*AP*TP*TP*CP*GP*GP*A)-3'), DNA (5'-D(*CP*CP*GP*AP*AP*TP*GP*AP*AP*TP*GP*AP*AP*TP*GP*AP*AP*TP*GP*GP*T)-3'), Pituitary-specific positive transcription factor 1 著者 Agarwal, S, Cho, T.Y. 登録日 2017-06-29 公開日 2017-11-22 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.15 Å) 主引用文献 Biochemical and structural characterization of a novel cooperative binding mode by Pit-1 with CATT repeats in the macrophage migration inhibitory factor promoter. Nucleic Acids Res., 46, 2018
5ZJT	Structure of AbdB/Exd complex bound to a 'Black14' DNA sequence 分子名称: DNA (5'-D(*GP*CP*AP*TP*GP*AP*TP*AP*AP*AP*TP*GP*AP*C)-3'), DNA (5'-D(*GP*TP*CP*AP*TP*TP*TP*AP*TP*CP*AP*TP*GP*C)-3'), Homeobox protein abdominal-B, ... 著者 Zeiske, T, Baburajendran, N, Kaczynska, A, Mann, R, Honig, B, Shapiro, L, Palmer, A.G. 登録日 2018-03-22 公開日 2018-08-29 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Intrinsic DNA Shape Accounts for Affinity Differences between Hox-Cofactor Binding Sites. Cell Rep, 24, 2018
5ZJS	Structure of AbdB/Exd complex bound to a 'Blue14' DNA sequence 分子名称: DNA (5'-D(*GP*CP*AP*TP*GP*AP*TP*TP*AP*AP*TP*GP*AP*C)-3'), DNA (5'-D(*GP*TP*CP*AP*TP*TP*AP*AP*TP*CP*AP*TP*GP*C)-3'), Homeobox protein abdominal-B, ... 著者 Baburajendran, N, Zeiske, T, Kaczynska, A, Mann, R, Honig, B, Shapiro, L, Palmer, A.G. 登録日 2018-03-22 公開日 2018-08-29 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.896 Å) 主引用文献 Intrinsic DNA Shape Accounts for Affinity Differences between Hox-Cofactor Binding Sites. Cell Rep, 24, 2018
5ZJR	Structure of AbdB/Exd complex bound to a 'Magenta14' DNA sequence 分子名称: DNA (5'-D(*GP*TP*CP*GP*TP*AP*AP*AP*TP*CP*AP*TP*GP*C)-3'), DNA (5'-D(P*GP*CP*AP*TP*GP*AP*TP*TP*TP*AP*CP*GP*AP*C)-3'), Homeobox protein abdominal-B, ... 著者 Zeiske, T, Baburajendran, N, Kaczynska, A, Mann, R, Honig, B, Shapiro, L, Palmer, A.G. 登録日 2018-03-22 公開日 2018-08-29 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (3.03 Å) 主引用文献 Intrinsic DNA Shape Accounts for Affinity Differences between Hox-Cofactor Binding Sites. Cell Rep, 24, 2018
1MH4	maltose binding-a1 homeodomain protein chimera, crystal form II 分子名称: maltose binding-a1 homeodomain protein chimera 著者 Ke, A, Wolberger, C. 登録日 2002-08-19 公開日 2002-09-18 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Insights into binding cooperativity of MATa1/MATalpha2 from the crystal structure of a MATa1 homeodomain-maltose binding protein chimera Protein Sci., 12, 2003
1O4X	TERNARY COMPLEX OF THE DNA BINDING DOMAINS OF THE OCT1 AND SOX2 TRANSCRIPTION FACTORS WITH A 19MER OLIGONUCLEOTIDE FROM THE HOXB1 REGULATORY ELEMENT 分子名称: 5'-D(*CP*AP*TP*TP*AP*GP*CP*AP*TP*GP*AP*CP*AP*AP*AP*GP*AP*CP*A)-3', 5'-D(*TP*GP*TP*CP*TP*TP*TP*GP*TP*CP*AP*TP*GP*CP*TP*AP*AP*TP*G)-3', Transcription factor SOX-2, ... 著者 Clore, G.M, Williams, D.C. 登録日 2003-07-17 公開日 2004-01-27 最終更新日 2023-12-27 実験手法 SOLUTION NMR 主引用文献 Molecular basis for synergistic transcriptional activation by Oct1 and Sox2 revealed from the solution structure of the 42-kDa Oct1.Sox2.Hoxb1-DNA ternary transcription factor complex. J.Biol.Chem., 279, 2004
1OCT	CRYSTAL STRUCTURE OF THE OCT-1 POU DOMAIN BOUND TO AN OCTAMER SITE: DNA RECOGNITION WITH TETHERED DNA-BINDING MODULES 分子名称: DNA (5'-D(*AP*CP*CP*TP*TP*AP*TP*TP*TP*GP*CP*AP*TP*AP*C)-3'), DNA (5'-D(*TP*GP*TP*AP*TP*GP*CP*AP*AP*AP*TP*AP*AP*GP*G)-3'), PROTEIN (OCT-1 POU DOMAIN) 著者 Klemm, J.D, Rould, M.A, Aurora, R, Herr, W, Pabo, C.O. 登録日 1994-05-09 公開日 1994-08-31 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Crystal structure of the Oct-1 POU domain bound to an octamer site: DNA recognition with tethered DNA-binding modules. Cell(Cambridge,Mass.), 77, 1994

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