4XRS
Heterodimeric complex of transcription factors MEIS1 and DLX3 on specific DNA
Summary for 4XRS
Entry DOI | 10.2210/pdb4xrs/pdb |
Descriptor | DNA (5'-D(P*CP*AP*AP*TP*TP*AP*TP*CP*CP*TP*GP*TP*CP*AP*A)-3'), DNA (5'-D(P*AP*CP*AP*AP*TP*TP*AP*TP*CP*CP*TP*GP*TP*CP*AP*AP*C)-3'), DNA (5'-D(P*GP*TP*TP*GP*AP*CP*AP*GP*GP*AP*TP*AP*AP*TP*TP*GP*TP*T)-3'), ... (6 entities in total) |
Functional Keywords | transcription, heterodimer, dna |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 8 |
Total formula weight | 47717.00 |
Authors | Jorma, A.,Yin, Y.,Nitta, K.R.,Dave, K.,Enge, M.,Kivioja, T.,Popov, A.,Morgunova, E.,Taipale, J. (deposition date: 2015-01-21, release date: 2015-11-04, Last modification date: 2024-01-10) |
Primary citation | Jolma, A.,Yin, Y.,Nitta, K.R.,Dave, K.,Popov, A.,Taipale, M.,Enge, M.,Kivioja, T.,Morgunova, E.,Taipale, J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature, 527:384-388, 2015 Cited by PubMed: 26550823DOI: 10.1038/nature15518 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.5 Å) |
Structure validation
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