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4XRS

Heterodimeric complex of transcription factors MEIS1 and DLX3 on specific DNA

Functional Information from GO Data
ChainGOidnamespacecontents
A0003677molecular_functionDNA binding
A0006355biological_processregulation of DNA-templated transcription
B0003677molecular_functionDNA binding
B0006355biological_processregulation of DNA-templated transcription
G0000981molecular_functionDNA-binding transcription factor activity, RNA polymerase II-specific
G0003677molecular_functionDNA binding
G0006355biological_processregulation of DNA-templated transcription
I0000981molecular_functionDNA-binding transcription factor activity, RNA polymerase II-specific
I0003677molecular_functionDNA binding
I0006355biological_processregulation of DNA-templated transcription
Functional Information from PROSITE/UniProt
site_idPS00027
Number of Residues24
DetailsHOMEOBOX_1 'Homeobox' domain signature. LAaqLgLTqtQVKIWFqNrrskfK
ChainResidueDetails
GLEU162-LYS185

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues60
DetailsRegion: {"description":"Interaction with DNA","evidences":[{"source":"PubMed","id":"26550823","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"28473536","evidenceCode":"ECO:0000305"}]}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues100
DetailsRegion: {"description":"Interaction with DNA","evidences":[{"source":"PubMed","id":"26550823","evidenceCode":"ECO:0000305"}]}
ChainResidueDetails

239803

PDB entries from 2025-08-06

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