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5FLV

Crystal structure of NKX2-5 and TBX5 bound to the Nppa promoter region

Summary for 5FLV
Entry DOI10.2210/pdb5flv/pdb
Related5FM6 5FM7
DescriptorHOMEOBOX PROTEIN NKX-2.5, T-BOX TRANSCRIPTION FACTOR TBX5, 5'-D(*TP*CP*TP*TP*CP*TP*CP*AP*CP*AP*CP*CP*TP*TP *TP*GP*AP*AP*GP*TP*GP*G)-3', 5'-D(*AP*CP*CP*AP*CP*TP*TP*CP*AP*AP*AP*GP*GP*TP *GP*TP*GP*AP*GP*AP*AP*G)-3', ... (4 entities in total)
Functional Keywordstranscription
Biological sourceMUS MUSCULUS (HOUSE MOUSE)
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Cellular locationNucleus : P42582
Total number of polymer chains12
Total formula weight186190.66
Authors
Stirnimann, C.U.,Glatt, S.,Mueller, C.W. (deposition date: 2015-10-28, release date: 2016-02-10, Last modification date: 2024-01-10)
Primary citationLuna-Zurita, L.,Stirnimann, C.U.,Glatt, S.,Kaynak, B.L.,Thomas, S.,Baudin, F.,Samee, M.A.H.,He, D.,Small, E.M.,Mileikovsky, M.,Nagy, A.,Holloway, A.K.,Pollard, K.S.,Muller, C.W.,Bruneau, B.G.
Complex Interdependence Regulates Heterotypic Transcription Factor Distribution and Coordinates Cardiogenesis.
Cell(Cambridge,Mass.), 164:999-, 2016
Cited by
PubMed: 26875865
DOI: 10.1016/J.CELL.2016.01.004
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.005 Å)
Structure validation

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