5WC9

Human Pit-1 and 4xCATT DNA complex

Summary for 5WC9

• Entry DOI: 10.2210/pdb5wc9/pdb
• Descriptor: Pituitary-specific positive transcription factor 1, DNA (5'-D(*CP*CP*AP*TP*TP*CP*AP*TP*TP*CP*AP*TP*TP*CP*AP*TP*TP*CP*GP*GP*A)-3'), DNA (5'-D(*CP*CP*GP*AP*AP*TP*GP*AP*AP*TP*GP*AP*AP*TP*GP*AP*AP*TP*GP*GP*T)-3') (3 entities in total)
• Functional Keywords: transcription regulation, dna-protein complex, dna binding protein
• Biological source: Homo sapiens (Human); More
• Cellular location: Nucleus : P28069
• Total number of polymer chains: 8
• Total formula weight: 96804.21

Authors

Agarwal, S.,Cho, T.Y. (deposition date: 2017-06-29, release date: 2017-11-22, Last modification date: 2023-10-04)

• Primary citation: Agarwal, S.,Cho, T.Y.; Biochemical and structural characterization of a novel cooperative binding mode by Pit-1 with CATT repeats in the macrophage migration inhibitory factor promoter.; Nucleic Acids Res., 46:929-941, 2018; PubMed: 29186613; DOI: 10.1093/nar/gkx1183

Experimental method

X-RAY DIFFRACTION (3.15 Å)