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5WC9

Human Pit-1 and 4xCATT DNA complex

Functional Information from GO Data
ChainGOidnamespacecontents
A0000981molecular_functionDNA-binding transcription factor activity, RNA polymerase II-specific
A0003677molecular_functionDNA binding
A0003700molecular_functionDNA-binding transcription factor activity
A0006355biological_processregulation of DNA-templated transcription
B0000981molecular_functionDNA-binding transcription factor activity, RNA polymerase II-specific
B0003677molecular_functionDNA binding
B0003700molecular_functionDNA-binding transcription factor activity
B0006355biological_processregulation of DNA-templated transcription
E0000981molecular_functionDNA-binding transcription factor activity, RNA polymerase II-specific
E0003677molecular_functionDNA binding
E0003700molecular_functionDNA-binding transcription factor activity
E0006355biological_processregulation of DNA-templated transcription
F0000981molecular_functionDNA-binding transcription factor activity, RNA polymerase II-specific
F0003677molecular_functionDNA binding
F0003700molecular_functionDNA-binding transcription factor activity
F0006355biological_processregulation of DNA-templated transcription
Functional Information from PROSITE/UniProt
site_idPS00027
Number of Residues24
DetailsHOMEOBOX_1 'Homeobox' domain signature. MAeeLnLEkeVVRVWFcNrrqreK
ChainResidueDetails
BMET124-LYS147

site_idPS00035
Number of Residues13
DetailsPOU_1 POU-specific (POUs) domain signature 1. RRIkLGYtQtNVG
ChainResidueDetails
BARG19-GLY31

site_idPS00465
Number of Residues14
DetailsPOU_2 POU-specific (POUs) domain signature 2. SQTTICRFEnLqLS
ChainResidueDetails
BSER43-SER56

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues236
DetailsDNA_BIND: Homeobox => ECO:0000255|PROSITE-ProRule:PRU00108
ChainResidueDetails
BLYS91-LYS150
ALYS91-LYS150
ELYS91-LYS150
FLYS91-LYS150

238268

PDB entries from 2025-07-02

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