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4ORZ
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HIV-1 Nef protein in complex with single domain antibody sdAb19 and an engineered Hck SH3 domain
分子名称: Protein Nef, Tyrosine-protein kinase HCK, single domain antibody sdAb19
著者Geyer, M, Lulf, S.
登録日2014-02-12
公開日2014-03-26
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for the inhibition of HIV-1 Nef by a high-affinity binding single-domain antibody.
Retrovirology, 11, 2014
5JMQ
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BU of 5jmq by Molmil
Crystal Structure of Mus musculus Protein Arginine Methyltransferase 2 with CP3
分子名称: 1,2-ETHANEDIOL, 9-[(5E)-7-carbamimidamido-5,6,7-trideoxy-beta-D-ribo-hept-5-enofuranosyl]-9H-purin-6-amine, CALCIUM ION, ...
著者Cura, V, Troffer-Charlier, N, Marechal, N, Bonnefond, L, Cavarelli, J.
登録日2016-04-29
公開日2017-05-10
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.795 Å)
主引用文献Structural studies of protein arginine methyltransferase 2 reveal its interactions with potential substrates and inhibitors.
Febs J., 284, 2017
2ROL
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BU of 2rol by Molmil
Structural Basis of PxxDY motif recognition in SH3 binding
分子名称: 12-meric peptide from T-cell surface glycoprotein CD3 epsilon chain, Epidermal growth factor receptor kinase substrate 8-like protein 1
著者Aitio, O, Hellman, M, Kesti, T, Kleino, I, Samuilova, O, Tossavainen, H, Paakkonen, K, Saksela, K, Permi, P.
登録日2008-04-02
公開日2009-03-03
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structural basis of PxxDY motif recognition in SH3 binding
J.Mol.Biol., 382, 2008
2XKX
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BU of 2xkx by Molmil
Single particle analysis of PSD-95 in negative stain
分子名称: DISKS LARGE HOMOLOG 4
著者Fomina, S, Howard, T.D, Sleator, O.K, Golovanova, M, O'Ryan, L, Leyland, M.L, Grossmann, J.G, Collins, R.F, Prince, S.M.
登録日2010-07-15
公開日2011-07-20
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (22.9 Å), SOLUTION SCATTERING
主引用文献Self-Directed Assembly and Clustering of the Cytoplasmic Domains of Inwardly Rectifying Kir2.1 Potassium Channels on Association with Psd-95
Biochim.Biophys.Acta, 1808, 2011
5NUH
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BU of 5nuh by Molmil
Crystal structure of SIVmac239 Nef bound to an engineered Hck SH3 domain
分子名称: Protein Nef, Tyrosine-protein kinase HCK,Tyrosine-protein kinase HCK
著者Horenkamp, F.A, Anand, K, Geyer, M.
登録日2017-04-30
公開日2017-08-16
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.78 Å)
主引用文献Endocytic sorting motif interactions involved in Nef-mediated downmodulation of CD4 and CD3.
Nat Commun, 8, 2017
1AVZ
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BU of 1avz by Molmil
V-1 NEF PROTEIN IN COMPLEX WITH WILD TYPE FYN SH3 DOMAIN
分子名称: FYN TYROSINE KINASE, NEGATIVE FACTOR
著者Arold, S, Franken, P, Dumas, C.
登録日1997-09-23
公開日1998-03-25
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The crystal structure of HIV-1 Nef protein bound to the Fyn kinase SH3 domain suggests a role for this complex in altered T cell receptor signaling.
Structure, 5, 1997
4N78
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BU of 4n78 by Molmil
The WAVE Regulatory Complex Links Diverse Receptors to the Actin Cytoskeleton
分子名称: Abl interactor 2, CHLORIDE ION, Cytoplasmic FMR1-interacting protein 1, ...
著者Chen, Z.C.
登録日2013-10-15
公開日2014-02-05
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.43 Å)
主引用文献The WAVE Regulatory Complex Links Diverse Receptors to the Actin Cytoskeleton.
Cell(Cambridge,Mass.), 156, 2014
1KJW
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BU of 1kjw by Molmil
SH3-Guanylate Kinase Module from PSD-95
分子名称: POSTSYNAPTIC DENSITY PROTEIN 95, SULFATE ION
著者McGee, A.W, Dakoji, S.R, Olsen, O, Bredt, D.S, Lim, W.A, Prehoda, K.E.
登録日2001-12-05
公開日2002-01-09
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of the SH3-Guanylate Kinase Module from PSD-95 Suggests a Mechanism for Regulated Assembly of MAGUK Scaffolding Proteins
Mol.Cell, 8, 2001
1NG2
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BU of 1ng2 by Molmil
Structure of autoinhibited p47phox
分子名称: Neutrophil cytosolic factor 1
著者Groemping, Y, Lapouge, K, Smerdon, S.J, Rittinger, K.
登録日2002-12-16
公開日2003-05-20
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Molecular basis of phosphorylation-induced activation of the NADPH oxidase
Cell(Cambridge,Mass.), 113, 2003
1U5S
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BU of 1u5s by Molmil
NMR structure of the complex between Nck-2 SH3 domain and PINCH-1 LIM4 domain
分子名称: Cytoplasmic protein NCK2, PINCH protein, ZINC ION
著者Vaynberg, J, Fukuda, T, Vinogradova, O, Velyvis, A, Ng, L, Wu, C, Qin, J.
登録日2004-07-28
公開日2005-04-05
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure of an ultraweak protein-protein complex and its crucial role in regulation of cell morphology and motility.
Mol.Cell, 17, 2005
1UEC
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BU of 1uec by Molmil
Crystal structure of autoinhibited form of tandem SH3 domain of p47phox
分子名称: Neutrophil cytosol factor 1
著者Yuzawa, S, Suzuki, N.N, Fujioka, Y, Ogura, K, Sumimoto, H, Inagaki, F.
登録日2003-05-11
公開日2003-05-27
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献A molecular mechanism for autoinhibition of the tandem SH3 domains of p47phox, the regulatory subunit of the phagocyte NADPH oxidase
Genes Cells, 9, 2004
1EFN
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BU of 1efn by Molmil
HIV-1 NEF PROTEIN IN COMPLEX WITH R96I MUTANT FYN SH3 DOMAIN
分子名称: FYN TYROSINE KINASE, HIV-1 NEF PROTEIN, TRIMETHYL LEAD ION
著者Lee, C.-H, Kuriyan, J.
登録日1996-06-29
公開日1997-01-11
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of the conserved core of HIV-1 Nef complexed with a Src family SH3 domain.
Cell(Cambridge,Mass.), 85, 1996
1JXM
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BU of 1jxm by Molmil
CRYSTAL STRUCTURE OF THE GMP BOUND SH3-HOOK-GK FRAGMENT OF PSD-95
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, GUANIDINE, GUANOSINE-5'-MONOPHOSPHATE, ...
著者Tavares, G.A, Panepucci, E.H, Brunger, A.T.
登録日2001-09-07
公開日2002-01-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural characterization of the intramolecular interaction between the SH3 and guanylate kinase domains of PSD-95.
Mol.Cell, 8, 2001
1JXO
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BU of 1jxo by Molmil
Crystal Structure of the SH3-HOOK-GK Fragment of PSD-95
分子名称: postsynaptic density protein
著者Tavares, G.A, Panepucci, E.H, Brunger, A.T.
登録日2001-09-07
公開日2002-01-16
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural characterization of the intramolecular interaction between the SH3 and guanylate kinase domains of PSD-95.
Mol.Cell, 8, 2001
1K4U
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BU of 1k4u by Molmil
Solution structure of the C-terminal SH3 domain of p67phox complexed with the C-terminal tail region of p47phox
分子名称: PHAGOCYTE NADPH OXIDASE SUBUNIT P47PHOX, PHAGOCYTE NADPH OXIDASE SUBUNIT P67PHOX
著者Kami, K, Takeya, R, Sumimoto, H, Kohda, D.
登録日2001-10-08
公開日2002-04-08
最終更新日2021-11-10
実験手法SOLUTION NMR
主引用文献Diverse recognition of non-PxxP peptide ligands by the SH3 domains from p67(phox), Grb2 and Pex13p.
EMBO J., 21, 2002
1W70
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BU of 1w70 by Molmil
SH3 domain of p40phox complexed with C-terminal polyProline region of p47phox
分子名称: NEUTROPHIL CYTOSOL FACTOR 1, NEUTROPHIL CYTOSOL FACTOR 4, SULFATE ION, ...
著者Massenet, C, Chenavas, S, Cohen-Addad, C, Dagher, M.-C, Brandolin, G, Pebay-Peyroula, E, Fieschi, F.
登録日2004-08-26
公開日2005-01-18
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.46 Å)
主引用文献Effects of P47Phox C-Terminus Phosphorylation on Binding Interactions with P40Phox and P67Phox: Structural and Functional Comparison of P40Phox P67Phox SH3 Domains
J.Biol.Chem., 280, 2005
1YCS
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BU of 1ycs by Molmil
P53-53BP2 COMPLEX
分子名称: 53BP2, P53, ZINC ION
著者Gorina, S, Pavletich, N.P.
登録日1996-09-30
公開日1997-11-19
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of the p53 tumor suppressor bound to the ankyrin and SH3 domains of 53BP2.
Science, 274, 1996
2DX1
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BU of 2dx1 by Molmil
Crystal structure of RhoGEF protein Asef
分子名称: Rho guanine nucleotide exchange factor 4
著者Murayama, K, Kato-Murayama, M, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2006-08-22
公開日2007-01-02
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.36 Å)
主引用文献Crystal structure of the rac activator, Asef, reveals its autoinhibitory mechanism
J.Biol.Chem., 282, 2007
2DYB
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BU of 2dyb by Molmil
The crystal structure of human p40(phox)
分子名称: Neutrophil cytosol factor 4
著者Honbou, K.
登録日2006-09-08
公開日2007-01-23
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Full-length p40phox structure suggests a basis for regulation mechanism of its membrane binding.
Embo J., 26, 2007
2JT4
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BU of 2jt4 by Molmil
Solution Structure of the Sla1 SH3-3-Ubiquitin Complex
分子名称: Cytoskeleton assembly control protein SLA1, Ubiquitin
著者He, Y, Radhakrishnan, I.
登録日2007-07-18
公開日2007-09-25
最終更新日2022-03-16
実験手法SOLUTION NMR
主引用文献Structural Basis for Ubiquitin Recognition by SH3 Domains
J.Mol.Biol., 373, 2007
2KNB
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BU of 2knb by Molmil
Solution NMR structure of the parkin Ubl domain in complex with the endophilin-A1 SH3 domain
分子名称: E3 ubiquitin-protein ligase parkin, Endophilin-A1
著者Trempe, J, Guennadi, K, Edna, C.M, Kalle, G.
登録日2009-08-20
公開日2009-12-22
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献SH3 domains from a subset of BAR proteins define a Ubl-binding domain and implicate parkin in synaptic ubiquitination.
Mol.Cell, 36, 2009
2KBT
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Attachment of an NMR-invisible solubility enhancement tag (INSET) using a sortase-mediated protein ligation method
分子名称: Proto-oncogene vav,Immunoglobulin G-binding protein G
著者Kumeta, H, Kobashigawa, Y, Ogura, K, Inagaki, F.
登録日2008-12-07
公開日2009-02-03
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Attachment of an NMR-invisible solubility enhancement tag using a sortase-mediated protein ligation method
J.Biomol.Nmr, 43, 2009
2L3S
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BU of 2l3s by Molmil
Structure of the autoinhibited Crk
分子名称: Autoinhibited Crk protein
著者Kalodimos, C.G, Sarkar, P, Saleh, T, Tzeng, S.R, Birge, R.
登録日2010-09-21
公開日2010-12-08
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structural basis for regulation of the Crk signaling protein by a proline switch.
Nat.Chem.Biol., 7, 2011
2LZ6
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BU of 2lz6 by Molmil
Distinct ubiquitin binding modes exhibited by sh3 domains: molecular determinants and functional implications
分子名称: CD2-associated protein, Ubiquitin
著者Ortega-Roldan, J, Azuaga, A, Blackledge, M, Van Nuland, N.
登録日2012-09-24
公開日2013-10-02
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Distinct Ubiquitin Binding Modes Exhibited by SH3 Domains: Molecular Determinants and Functional Implications.
Plos One, 8, 2013
2MOX
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solution structure of tandem SH3 domain of Sorbin and SH3 domain-containing protein 1
分子名称: Sorbin and SH3 domain-containing protein 1
著者Zhao, D, Wang, C, Zhang, J, Wu, J, Shi, Y, Zhang, Z, Gong, Q.
登録日2014-05-07
公開日2014-05-28
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural investigation of the interaction between the tandem SH3 domains of c-Cbl-associated protein and vinculin
J.Struct.Biol., 187, 2014

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