2ROL

Structural Basis of PxxDY motif recognition in SH3 binding

Summary for 2ROL

Entry DOI	10.2210/pdb2rol/pdb
NMR Information	BMRB: 11040
Descriptor	Epidermal growth factor receptor kinase substrate 8-like protein 1, 12-meric peptide from T-cell surface glycoprotein CD3 epsilon chain (2 entities in total)
Functional Keywords	eps8l1, cd3e, sh3, complex structure, alternative splicing, coiled coil, cytoplasm, sh3 domain, immunoglobulin domain, membrane, phosphoprotein, receptor, transmembrane, splicing-signaling protein complex, splicing/signaling protein
Biological source	Homo sapiens (Human) More
Total number of polymer chains	2
Total formula weight	8695.70
Authors	Aitio, O.,Hellman, M.,Kesti, T.,Kleino, I.,Samuilova, O.,Tossavainen, H.,Paakkonen, K.,Saksela, K.,Permi, P. (deposition date: 2008-04-02, release date: 2009-03-03, Last modification date: 2020-02-26)
Primary citation	Aitio, O.,Hellman, M.,Kesti, T.,Kleino, I.,Samuilova, O.,Paakkonen, K.,Tossavainen, H.,Saksela, K.,Permi, P. Structural basis of PxxDY motif recognition in SH3 binding J.Mol.Biol., 382:167-178, 2008 Cited by PubMed: 18644376 DOI: 10.1016/j.jmb.2008.07.008 PDB entries with the same primary citation
Experimental method	SOLUTION NMR

Structure validation