2ROL
Structural Basis of PxxDY motif recognition in SH3 binding
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Epidermal growth factor receptor kinase substrate 8-like protein 1 | polymer | 64 | 7301.2 | 1 | UniProt (Q8TE68) Pfam (PF00018) | Homo sapiens (Human) | Epidermal growth factor receptor pathway substrate 8-related protein 1, EPS8-like protein 1 |
| 2 | B (B) | 12-meric peptide from T-cell surface glycoprotein CD3 epsilon chain | polymer | 12 | 1394.5 | 1 | UniProt (P07766) Pfam (PF02189) | T-cell surface antigen T3/Leu-4 epsilon chain |
Sequence modifications
A: 478 - 537 (UniProt: Q8TE68)
| PDB | External Database | Details |
|---|---|---|
| Gly 474 | - | expression tag |
| Ser 475 | - | expression tag |
| Met 476 | - | expression tag |
| Gly 477 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 8695.7 | |
| All* | Total formula weight | 8695.7 |
