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7T57
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BU of 7t57 by Molmil
Cryo-EM structure of PCAT1 in the inward-facing narrow conformation under ATP turnover condition
Descriptor: ABC-type bacteriocin transporter, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Kieuvongngam, V, Chen, J.
Deposit date:2021-12-11
Release date:2022-02-02
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structures of the peptidase-containing ABC transporter PCAT1 under equilibrium and nonequilibrium conditions.
Proc.Natl.Acad.Sci.USA, 119, 2022
7T54
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BU of 7t54 by Molmil
Cryo-EM structure of ATP-bound PCAT1 in the outward-facing conformation
Descriptor: ABC-type bacteriocin transporter, ADENOSINE-5'-TRIPHOSPHATE
Authors:Kieuvongngam, V, Chen, J.
Deposit date:2021-12-11
Release date:2022-02-02
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Structures of the peptidase-containing ABC transporter PCAT1 under equilibrium and nonequilibrium conditions.
Proc.Natl.Acad.Sci.USA, 119, 2022
7MSZ
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BU of 7msz by Molmil
Mtb 70SIC in complex with MtbEttA at Trans_R1 state
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Cui, Z, Zhang, J.
Deposit date:2021-05-12
Release date:2022-02-02
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Interplay between an ATP-binding cassette F protein and the ribosome from Mycobacterium tuberculosis.
Nat Commun, 13, 2022
7MU0
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BU of 7mu0 by Molmil
MtbEttA in the ADP bound state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Energy-dependent translational throttle protein EttA, MAGNESIUM ION
Authors:Cui, Z, Zhang, J.
Deposit date:2021-05-14
Release date:2022-02-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Interplay between an ATP-binding cassette F protein and the ribosome from Mycobacterium tuberculosis.
Nat Commun, 13, 2022
7MSM
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BU of 7msm by Molmil
Mtb 70SIC in complex with MtbEttA at Trans_R0 state
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Cui, Z, Zhang, J.
Deposit date:2021-05-11
Release date:2022-02-02
Method:ELECTRON MICROSCOPY (2.79 Å)
Cite:Interplay between an ATP-binding cassette F protein and the ribosome from Mycobacterium tuberculosis.
Nat Commun, 13, 2022
7MSH
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BU of 7msh by Molmil
Mtb 70SIC in complex with MtbEttA at Pre_R1 state
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Cui, Z, Zhang, J.
Deposit date:2021-05-11
Release date:2022-02-02
Method:ELECTRON MICROSCOPY (3.23 Å)
Cite:Interplay between an ATP-binding cassette F protein and the ribosome from Mycobacterium tuberculosis.
Nat Commun, 13, 2022
7MSC
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BU of 7msc by Molmil
Mtb 70SIC in complex with MtbEttA at Pre_R0 state
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Cui, Z, Zhang, J.
Deposit date:2021-05-11
Release date:2022-02-02
Method:ELECTRON MICROSCOPY (2.97 Å)
Cite:Interplay between an ATP-binding cassette F protein and the ribosome from Mycobacterium tuberculosis.
Nat Commun, 13, 2022
7TBZ
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BU of 7tbz by Molmil
The structure of ABCA1 Y482C
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ATP-binding cassette, ...
Authors:Sun, Y, Li, X.
Deposit date:2021-12-22
Release date:2022-01-26
Last modified:2023-05-24
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Cholesterol efflux mechanism revealed by structural analysis of human ABCA1 conformational states.
Nat Cardiovasc Res, 1, 2022
7TBW
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BU of 7tbw by Molmil
The structure of ATP-bound ABCA1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Sun, Y, Li, X.
Deposit date:2021-12-22
Release date:2022-01-26
Last modified:2023-05-24
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Cholesterol efflux mechanism revealed by structural analysis of human ABCA1 conformational states.
Nat Cardiovasc Res, 1, 2022
7TC0
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BU of 7tc0 by Molmil
The structure of human ABCA1 in digitonin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ATP-binding cassette, ...
Authors:Sun, Y, Li, X.
Deposit date:2021-12-22
Release date:2022-01-26
Last modified:2023-05-24
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Cholesterol efflux mechanism revealed by structural analysis of human ABCA1 conformational states.
Nat Cardiovasc Res, 1, 2022
7TBY
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BU of 7tby by Molmil
The structure of human ABCA1 in nanodisc
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ATP-binding cassette, ...
Authors:Sun, Y, Li, X.
Deposit date:2021-12-22
Release date:2022-01-26
Last modified:2023-05-24
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Cholesterol efflux mechanism revealed by structural analysis of human ABCA1 conformational states.
Nat Cardiovasc Res, 1, 2022
7OW8
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BU of 7ow8 by Molmil
CryoEM structure of the ABC transporter BmrA E504A mutant in complex with ATP-Mg
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Multidrug resistance ABC transporter ATP-binding/permease protein BmrA
Authors:Gobet, A, Schoehn, G, Falson, P, Chaptal, V.
Deposit date:2021-06-17
Release date:2022-01-19
Last modified:2022-02-02
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Substrate-bound and substrate-free outward-facing structures of a multidrug ABC exporter.
Sci Adv, 8, 2022
7RR9
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BU of 7rr9 by Molmil
Cryo-EM Structure of Nanodisc reconstituted ABCD1 in nucleotide bound outward open conformation
Descriptor: ATP-binding cassette sub-family D member 1, CHOLESTEROL, MAGNESIUM ION, ...
Authors:Alam, A, Le, L.T.M, Thompson, J.R.
Deposit date:2021-08-09
Release date:2022-01-19
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structures of the human peroxisomal fatty acid transporter ABCD1 in a lipid environment
Commun Biol, 5, 2022
7RRA
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BU of 7rra by Molmil
Cryo-EM Structure of Nanodisc reconstituted ABCD1 in inward open conformation
Descriptor: ATP-binding cassette sub-family D member 1
Authors:Alam, A, Le, L.T.M, Thompson, J.R.
Deposit date:2021-08-09
Release date:2022-01-19
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Structures of the human peroxisomal fatty acid transporter ABCD1 in a lipid environment
Commun Biol, 5, 2022
7ROQ
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BU of 7roq by Molmil
Alternative Structure of Human ABCA1
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Aller, S.G.
Deposit date:2021-08-01
Release date:2022-01-19
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Refined ABCA1 with Domain-swapped Regulatory Domains
Plos One, 2022
7DV5
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BU of 7dv5 by Molmil
Human bile salt exporter ABCB11 in complex with taurocholate
Descriptor: Bile salt export pump, TAUROCHOLIC ACID
Authors:Wang, L, How, W.T, Chen, Y.
Deposit date:2021-01-12
Release date:2022-01-19
Last modified:2022-05-18
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structures of human bile acid exporter ABCB11 reveal a transport mechanism facilitated by two tandem substrate-binding pockets.
Cell Res., 32, 2022
7SVR
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BU of 7svr by Molmil
The complex of dephosphorylated human cystic fibrosis transmembrane conductance regulator (CFTR) and Lumacaftor (VX-809)
Descriptor: Cystic fibrosis transmembrane conductance regulator, Lumacaftor
Authors:Fiedorczuk, K, Chen, J.
Deposit date:2021-11-19
Release date:2022-01-12
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Mechanism of CFTR correction by type I folding correctors.
Cell, 185, 2022
7SVD
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BU of 7svd by Molmil
The complex of phosphorylated human cystic fibrosis transmembrane conductance regulator (CFTR) with ATP/Mg and Lumacaftor (VX-809)
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CHOLESTEROL, Cystic fibrosis transmembrane conductance regulator, ...
Authors:Fiedorczuk, K, Chen, J.
Deposit date:2021-11-18
Release date:2022-01-12
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Mechanism of CFTR correction by type I folding correctors.
Cell, 185, 2022
7SV7
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BU of 7sv7 by Molmil
The complex of phosphorylated human cystic fibrosis transmembrane conductance regulator (CFTR) with ATP/Mg and Tezacaftor (VX-661)
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CHOLESTEROL, Cystic fibrosis transmembrane conductance regulator, ...
Authors:Fiedorczuk, K, Chen, J.
Deposit date:2021-11-18
Release date:2022-01-12
Last modified:2022-11-02
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Mechanism of CFTR correction by type I folding correctors.
Cell, 185, 2022
7BG4
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BU of 7bg4 by Molmil
Multidrug resistance transporter BmrA mutant E504A bound with ATP, Mg, and Rhodamine 6G solved by Cryo-EM
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Lipid A export ATP-binding/permease protein MsbA, MAGNESIUM ION, ...
Authors:Wiseman, B, Chaptal, V, Zampieri, V, Magnard, S, Hogbom, M, Falson, P.
Deposit date:2021-01-05
Release date:2022-01-12
Last modified:2022-02-02
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Substrate-bound and substrate-free outward-facing structures of a multidrug ABC exporter.
Sci Adv, 8, 2022
7BCW
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BU of 7bcw by Molmil
Structure of MsbA in Salipro with ADP vanadate
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ADENOSINE-5'-DIPHOSPHATE, ATP-dependent lipid A-core flippase, ...
Authors:Traore, D.A.K, Tidow, H.
Deposit date:2020-12-21
Release date:2022-01-12
Last modified:2022-05-25
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Cryo-EM structure of MsbA in saposin-lipid nanoparticles (Salipro) provides insights into nucleotide coordination.
Febs J., 289, 2022
7O9W
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BU of 7o9w by Molmil
Encequidar-bound human P-glycoprotein in complex with UIC2-Fab
Descriptor: Multidrug resistance protein 1, UIC2 Fab-fragment heavy chain, UIC2 Fab-fragment light chain, ...
Authors:Nosol, K, Locher, K.P.
Deposit date:2021-04-17
Release date:2022-01-12
Last modified:2022-01-26
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Discovery and Characterization of Potent Dual P-Glycoprotein and CYP3A4 Inhibitors: Design, Synthesis, Cryo-EM Analysis, and Biological Evaluations.
J.Med.Chem., 65, 2022
7M33
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BU of 7m33 by Molmil
The structure of Bacillus subtilis BmrCD in the inward-facing conformation bound to Hoechst-33342 and ATP
Descriptor: 2'-(4-ETHOXYPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI-BENZIMIDAZOLE, ADENOSINE-5'-TRIPHOSPHATE, Probable multidrug resistance ABC transporter ATP-binding/permease protein YheH, ...
Authors:Thaker, T.M, Tomasiak, T.M.
Deposit date:2021-03-18
Release date:2022-01-05
Last modified:2022-02-09
Method:ELECTRON MICROSCOPY (3.55 Å)
Cite:Asymmetric drug binding in an ATP-loaded inward-facing state of an ABC transporter.
Nat.Chem.Biol., 18, 2022
7PSM
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BU of 7psm by Molmil
S. cerevisiae Atm1 in MSP1D1 nanodiscs with bound AMP-PNP and Mg2+
Descriptor: (1R)-2-{[(R)-(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(DODECANOYLOXY)METHYL]ETHYL (9Z)-OCTADEC-9-ENOATE, Iron-sulfur clusters transporter ATM1, mitochondrial, ...
Authors:Ellinghaus, T.L, Kuehlbrandt, W.
Deposit date:2021-09-23
Release date:2021-12-29
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Conformational changes in the yeast mitochondrial ABC transporter Atm1 during the transport cycle.
Sci Adv, 7, 2021
7PSL
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BU of 7psl by Molmil
S. cerevisiae Atm1 in MSP1D1 nanodiscs in nucleotide-free state
Descriptor: (1R)-2-{[(R)-(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(DODECANOYLOXY)METHYL]ETHYL (9Z)-OCTADEC-9-ENOATE, Iron-sulfur clusters transporter ATM1, mitochondrial, ...
Authors:Ellinghaus, T.L, Kuehlbrandt, W.
Deposit date:2021-09-23
Release date:2021-12-29
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Conformational changes in the yeast mitochondrial ABC transporter Atm1 during the transport cycle.
Sci Adv, 7, 2021

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