PDB: 866 件ウェブページステータス検索Chemie searchBIRD

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5WS4	Crystal structure of tripartite-type ABC transporter MacB from Acinetobacter baumannii 分子名称: 5'-O-[(R)-HYDROXY(THIOPHOSPHONOOXY)PHOSPHORYL]ADENOSINE, Macrolide export ATP-binding/permease protein MacB 著者 Murakami, S, Okada, U, Yamashita, E. 登録日 2016-12-05 公開日 2017-11-15 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Crystal structure of tripartite-type ABC transporter MacB from Acinetobacter baumannii. Nat Commun, 8, 2017
6AN5	Crystal Structure of The Nucelotide Binding Domain of an O-antigen polysaccharide ABC-transporter 分子名称: ABC transporter 著者 Zimmer, J, Bi, Y. 登録日 2017-08-12 公開日 2017-11-29 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (3.512 Å) 主引用文献 Architecture of a channel-forming O-antigen polysaccharide ABC transporter. Nature, 553, 2018
6AMX	Crystal Structure of Nucelotide Binding Domain of O-antigen polysaccharide ABC-transporter 分子名称: 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, ABC transporter 著者 Zimmer, J, Bi, Y. 登録日 2017-08-11 公開日 2017-11-29 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Architecture of a channel-forming O-antigen polysaccharide ABC transporter. Nature, 553, 2018
6B89	E. coli LptB in complex with ADP and novobiocin 分子名称: ADENOSINE-5'-DIPHOSPHATE, Lipopolysaccharide export system ATP-binding protein LptB, MAGNESIUM ION, ... 著者 May, J.M, Lazarus, M.B, Sherman, D.J, Owens, T.W, Mandler, M.D, Kahne, D.K. 登録日 2017-10-05 公開日 2017-12-06 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The Antibiotic Novobiocin Binds and Activates the ATPase That Powers Lipopolysaccharide Transport. J. Am. Chem. Soc., 139, 2017
6B8B	E. coli LptB in complex with ADP and a novobiocin derivative 分子名称: (3s,5s,7s)-N-{7-[(3-O-carbamoyl-6-deoxy-5-methyl-4-O-methyl-beta-D-gulopyranosyl)oxy]-4-hydroxy-8-methyl-2-oxo-2H-1-ben zopyran-3-yl}tricyclo[3.3.1.1~3,7~]decane-1-carboxamide, ADENOSINE-5'-DIPHOSPHATE, Lipopolysaccharide export system ATP-binding protein LptB, ... 著者 Mandler, M.D, Owens, T.W, Lazarus, M.B, May, J.M, Kahne, D.K. 登録日 2017-10-06 公開日 2017-12-06 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 The Antibiotic Novobiocin Binds and Activates the ATPase That Powers Lipopolysaccharide Transport. J. Am. Chem. Soc., 139, 2017
6BHU	Cryo-EM structure of ATP-bound, outward-facing bovine multidrug resistance protein 1 (MRP1) 分子名称: ADENOSINE-5'-TRIPHOSPHATE, CHOLESTEROL, MAGNESIUM ION, ... 著者 Johnson, Z.L, Chen, J. 登録日 2017-10-31 公開日 2017-12-27 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.14 Å) 主引用文献 ATP Binding Enables Substrate Release from Multidrug Resistance Protein 1. Cell, 172, 2018
5XU1	Structure of a non-canonical ABC transporter from Streptococcus pneumoniae R6 分子名称: ABC transporter ATP-binding protein, ABC transporter permeae, MAGNESIUM ION 著者 Yang, H.B, Jiang, Y.L, Hou, W.T, Chen, M.T, Chen, Y, Zhou, C.Z. 登録日 2017-06-22 公開日 2018-01-24 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Structure of a MacAB-like efflux pump from Streptococcus pneumoniae. Nat Commun, 9, 2018
6C3P	Cryo-EM structure of human KATP bound to ATP and ADP in propeller form 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ... 著者 Lee, K.P.K, Chen, J, MacKinnon, R. 登録日 2018-01-10 公開日 2018-01-24 実験手法 ELECTRON MICROSCOPY (5.6 Å) 主引用文献 Molecular structure of human KATP in complex with ATP and ADP. Elife, 6, 2017
6C3O	Cryo-EM structure of human KATP bound to ATP and ADP in quatrefoil form 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ... 著者 Lee, K.P.K, Chen, J, MacKinnon, R. 登録日 2018-01-10 公開日 2018-01-31 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Molecular structure of human KATP in complex with ATP and ADP Elife, 6, 2017
6C0V	Molecular structure of human P-glycoprotein in the ATP-bound, outward-facing conformation 分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Multidrug resistance protein 1 著者 Kim, Y.J, Chen, J. 登録日 2018-01-02 公開日 2018-01-31 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Molecular structure of human P-glycoprotein in the ATP-bound, outward-facing conformation. Science, 359, 2018
6FN1	Zosuquidar and UIC2 Fab complex of human-mouse chimeric ABCB1 (ABCB1HM) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Human-mouse chimeric ABCB1 (ABCBHM), UIC2 Antigen Binding Fragment Heavy Chain, ... 著者 Alam, A, Locher, K.P. 登録日 2018-02-02 公開日 2018-02-21 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (3.58 Å) 主引用文献 Structure of a zosuquidar and UIC2-bound human-mouse chimeric ABCB1. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6FN4	Apo form of UIC2 Fab complex of human-mouse chimeric ABCB1 (ABCB1HM) 分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, Apo form of Human-mouse chimeric ABCB1 (ABCB1HM) in complex with Antigen binding fragment of UIC2., ... 著者 Alam, A, Locher, K.P. 登録日 2018-02-02 公開日 2018-02-21 最終更新日 2021-06-02 実験手法 ELECTRON MICROSCOPY (4.14 Å) 主引用文献 Structure of a zosuquidar and UIC2-bound human-mouse chimeric ABCB1. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6ETI	Structure of inhibitor-bound ABCG2 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5D3(Fab) heavy chain variable domain, 5D3(Fab) light chain variable domain, ... 著者 Jackson, S.M, Manolaridis, I, Kowal, J, Zechner, M, Altmann, K.H, Locher, K.P. 登録日 2017-10-26 公開日 2018-04-11 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural basis of small-molecule inhibition of human multidrug transporter ABCG2. Nat. Struct. Mol. Biol., 25, 2018
6FFC	Structure of an inhibitor-bound ABC transporter 分子名称: ATP-binding cassette sub-family G member 2, ~{tert}-butyl 3-[(2~{S},5~{S},8~{S})-14-cyclopentyloxy-2-(2-methylpropyl)-4,7-bis(oxidanylidene)-3,6,17-triazatetracyclo[8.7.0.0^{3,8}.0^{11,16}]heptadeca-1(10),11,13,15-tetraen-5-yl]propanoate 著者 Jackson, S.M, Manolaridis, I, Kowal, J, Zechner, M, Taylor, N.M.I, Bause, M, Bauer, S, Bartholomaeus, R, Stahlberg, H, Bernhardt, G, Koenig, B, Buschauer, A, Altmann, K.H, Locher, K.P. 登録日 2018-01-06 公開日 2018-04-11 最終更新日 2019-12-11 実験手法 ELECTRON MICROSCOPY (3.56 Å) 主引用文献 Structural basis of small-molecule inhibition of human multidrug transporter ABCG2. Nat. Struct. Mol. Biol., 25, 2018
6FEQ	Structure of inhibitor-bound ABCG2 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 5D3(Fab) heavy chain variable domain, 5D3(Fab) light chain variable domain, ... 著者 Jackson, S.M, Manolaridis, I, Kowal, J, Zechner, M, Altmann, K.H, Locher, K.P. 登録日 2018-01-03 公開日 2018-04-11 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structural basis of small-molecule inhibition of human multidrug transporter ABCG2. Nat. Struct. Mol. Biol., 25, 2018
5YKF	Structure of pancreatic ATP-sensitive potassium channel bound with glibenclamide and ATPgammaS (3D class1 at 4.33A) 分子名称: 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11, ... 著者 Chen, L, Wu, J.X. 登録日 2017-10-14 公開日 2018-04-18 最終更新日 2019-11-06 実験手法 ELECTRON MICROSCOPY (4.33 Å) 主引用文献 Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels. Protein Cell, 9, 2018
5YKG	Structure of pancreatic ATP-sensitive potassium channel bound with glibenclamide and ATPgammaS (Class2 at 4.57A) 分子名称: 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11, ... 著者 Chen, L, Wu, J.X. 登録日 2017-10-14 公開日 2018-04-18 最終更新日 2018-06-13 実験手法 ELECTRON MICROSCOPY (4.57 Å) 主引用文献 Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels. Protein Cell, 9, 2018
5YKE	Structure of pancreatic ATP-sensitive potassium channel bound with glibenclamide and ATPgammaS (focused refinement on TM at 4.11A) 分子名称: 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11 著者 Chen, L, Wu, J.X. 登録日 2017-10-14 公開日 2018-04-18 最終更新日 2018-06-13 実験手法 ELECTRON MICROSCOPY (4.11 Å) 主引用文献 Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels. Protein Cell, 9, 2018
5YWC	Structure of pancreatic ATP-sensitive potassium channel bound with Mg-ADP (CTD class1 at 4.3A) 分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11, ... 著者 Chen, L, Wu, J.X. 登録日 2017-11-29 公開日 2018-05-02 最終更新日 2018-06-13 実験手法 ELECTRON MICROSCOPY (4.3 Å) 主引用文献 Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels. Protein Cell, 9, 2018
5YW9	Structure of pancreatic ATP-sensitive potassium channel bound with ATPgammaS (class1 5.0A) 分子名称: ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER 著者 Chen, L, Wu, J.X. 登録日 2017-11-29 公開日 2018-05-02 最終更新日 2018-06-13 実験手法 ELECTRON MICROSCOPY (5 Å) 主引用文献 Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels. Protein Cell, 9, 2018
5YW8	Structure of pancreatic ATP-sensitive potassium channel bound with ATPgammaS (all particles at 4.4A) 分子名称: ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER 著者 Chen, L, Wu, J.X. 登録日 2017-11-29 公開日 2018-05-02 最終更新日 2018-06-13 実験手法 ELECTRON MICROSCOPY (4.4 Å) 主引用文献 Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels. Protein Cell, 9, 2018
5YWD	Structure of pancreatic ATP-sensitive potassium channel bound with Mg-ADP (focused refinement of SUR1 ABC transporter module at 4.22A) 分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-binding cassette sub-family C member 8 isoform X2, MAGNESIUM ION 著者 Chen, L, Wu, J.X. 登録日 2017-11-29 公開日 2018-05-02 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels. Protein Cell, 9, 2018
5YW7	Structure of pancreatic ATP-sensitive potassium channel bound with glibenclamide and ATPgammaS (focused refinement on SUR1 ABC transporter module at 4.4A) 分子名称: 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, ATP-binding cassette sub-family C member 8 isoform X2, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER 著者 Chen, L, Wu, J.X. 登録日 2017-11-29 公開日 2018-05-02 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (4.4 Å) 主引用文献 Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels. Protein Cell, 9, 2018
5YWA	Structure of pancreatic ATP-sensitive potassium channel bound with ATPgammaS (CTD class 2 at 6.1A) 分子名称: ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER 著者 Chen, L, Wu, J.X. 登録日 2017-11-29 公開日 2018-05-02 最終更新日 2018-06-13 実験手法 ELECTRON MICROSCOPY (6.1 Å) 主引用文献 Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels. Protein Cell, 9, 2018
6BPP	E. coli MsbA in complex with LPS and inhibitor G092 分子名称: (2E)-3-{6-[(1S)-1-(3-amino-2,6-dichlorophenyl)ethoxy]-4-cyclopropylquinolin-3-yl}prop-2-enoic acid, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 3-HYDROXY-TETRADECANOIC ACID, ... 著者 Ho, H, Koth, C.M, Payandeh, J. 登録日 2017-11-24 公開日 2018-05-02 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.92 Å) 主引用文献 Structural basis for dual-mode inhibition of the ABC transporter MsbA. Nature, 557, 2018

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